Explore $100K+ Jobs in Michigan

Discover professional opportunities across Michigan with Ladders, where job seekers can explore vetted roles offering salaries of $100,000 or more. From established employers in Detroit to growing companies in Grand Rapids, Ann Arbor, Lansing, and other communities, Michigan offers career paths across a diverse range of industries and leadership levels.

Find Opportunities Across Michigan

Search jobs throughout the state, including major employment hubs such as Detroit, Grand Rapids, Ann Arbor, Lansing, and Kalamazoo. Depending on the role and employer, opportunities may offer on-site, hybrid, or remote work arrangements. Review each listing for location, compensation, responsibilities, and workplace expectations.

Explore Michigan Industries

Michigan is known for its automotive and advanced manufacturing industries, while also supporting opportunities in technology, healthcare, finance, engineering, supply chain, energy, and professional services. Employers seek experienced professionals for specialized individual-contributor roles as well as management and executive positions.

Build Your Next Career Move

Use Ladders to focus your search on vetted professional jobs paying $100,000 or more. Compare opportunities, identify roles that fit your experience, and tailor your résumé to highlight measurable results, leadership, and relevant expertise. Job availability and compensation vary by employer, location, and qualifications.

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1,000+

Physical Therapist Jobs in Michigan

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$148K - $256K *

Shape the future of data engineering by architecting scalable, cloud-native data platforms on Azure and Databricks. Influence the organization’s data practices to leverage AI-driven insights, driving...

United StatesRemote

Reposted 3 weeks ago

  •   8 - 10 years exp.  •   Hospitals & Medical Centers

$199K - $235K *

Unlock potential by designing and maintaining integrations that connect NodeZero with key security platforms. Collaborate with teams to enhance reliability and observability, ensuring seamless user ex...

United StatesRemote

2 days ago

  •   Less than 5 years exp.  •   Information Technology

$315K - $370K *

Join a team that's redefining offensive security by leading engineering efforts to transform research into scalable, customer-facing products. Drive strategy, execution, and innovation across multiple...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Information Technology

$100K - $120K *

Transform client relationships as you deliver elite service and expert risk management for high-net-worth clients. Drive retention and growth through proactive consulting and strategic market placemen...

United StatesRemote

Today

  •   Less than 5 years exp.  •   Finance & Insurance

$115K - $165K *

Transform your career by leading Red Team activities to assess and enhance security defenses. Collaborate with senior leadership, execute assessments, and provide strategic recommendations to safeguar...

United StatesRemote

Yesterday

  •   5 - 7 years exp.  •   Information Technology

$85K - $100K *

Elevate patient care by leading a dynamic nursing team, ensuring quality and innovation in service delivery while managing fiscal responsibilities and fostering collaborative relationships with health...

Yesterday

  •   Less than 5 years exp.  •   Healthcare

$80K - $95K *

Join a team that's dedicated to enhancing customer education and satisfaction through expert training on ultrasound products. This hybrid role involves travel and collaboration with healthcare profess...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Business Services

$80K - $95K *

Lead the configuration and support of Epic applications, ensuring seamless integration and optimal performance. Collaborate with teams to enhance workflows, troubleshoot issues, and drive project succ...

United StatesRemote

Today

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$150K - $180K *

Elevate your career by leading strategic client relationships and driving growth in a dynamic architecture and engineering firm. This senior role focuses on account management, project excellence, and...

2 weeks ago

  •   8 - 10 years exp.  •   Real Estate & Construction

$130K - $155K *

Elevate your career by joining a dynamic Medical Affairs team, where you'll lead Medical Information initiatives, ensure compliance, and drive strategic insights to support our innovative pipeline in...

United StatesRemote

4 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$160K - $200K *

Shape the future of pediatric care by expanding clinical services and education in Developmental Behavioral Pediatrics, collaborating with a dedicated team to enhance patient outcomes and foster medic...

3 days ago

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$180K - $220K *

Join a team that's dedicated to advancing neonatal care and education. Contribute to a leading Level IV NICU while engaging in research and clinical training. Ideal for passionate professionals eager...

1 week ago

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$95K - $115K *

Join a dynamic team to lead architectural projects from concept to completion, ensuring client satisfaction and project success. Oversee design, manage teams, and coordinate with stakeholders to deliv...

3 weeks ago

  •   11 - 15 years exp.  •   Real Estate & Construction

$115K - $151K *

Grow your career with a dynamic team focused on AI tool administration and governance. Collaborate across departments to enhance system connectivity and process automation while ensuring data privacy...

United StatesRemote

Reposted 2 days ago

  •   Less than 5 years exp.  •   Information Technology

$73K - $107K *

Join a dynamic team to oversee environmental compliance in construction projects. Collaborate with engineers and regulatory agencies to resolve complex issues and ensure adherence to environmental sta...

1 week ago

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$90K - $100K *

Join a team that's dedicated to optimizing payroll operations and compliance. This role supports payroll processing, reporting, and employee services, ensuring accuracy and scalability as the organiza...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Information Technology

$90K - $110K *

Join a dedicated cardiology team to provide high-quality, patient-centered care. This role emphasizes teamwork and professional growth, welcoming both experienced practitioners and new graduates eager...

2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$225K - $265K *

Shape the future of oncology by leading clinical studies in early-phase development. Collaborate with multidisciplinary teams to drive innovative therapies and ensure high-quality execution of clinica...

United StatesRemote

Reposted 6 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$177K - $338K *

Innovate the global medical strategy for a leading drug program. Drive launch readiness, evidence generation, and cross-functional partnerships while serving as the primary medical voice in product li...

RemoteRemote

Reposted 3 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$120K - $145K *

Shape complex, cross-functional programs that drive enterprise transformation, focusing on Customer Data Platform implementation and AI initiatives. Collaborate with diverse teams to ensure strategic...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Healthcare

$113K - $188K *

Shape the future of managed care by leading contract negotiations, performance monitoring, and strategic initiatives to optimize reimbursement and enhance payer relationships across healthcare service...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Business Services

$120K - $150K *

Shape the future of brand strategy by leading integrated initiatives, translating insights into actionable plans, and collaborating with cross-functional teams to deliver impactful solutions across as...

United StatesRemote

4 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$150K - $180K *

Unlock potential by driving sales strategy and value analysis, partnering with cross-functional teams to enhance proposals, pricing, and contracts. Lead market research and client engagement to optimi...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$150K - $180K *

Innovate scalable backend systems while leading architectural design and mentoring teams. This role combines hands-on coding with strategic leadership to align technical solutions with business goals...

RemoteRemote

5 days ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$75K - $95K *

Champion the development and implementation of ABA programs for individuals with autism and developmental disabilities, providing clinical supervision and collaborating with families to achieve treatm...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

Frequently Asked Questions (FAQ)

  • What kinds of $100,000+ jobs can I find in Michigan?question toggle

    Listings may include senior and executive roles in fields such as engineering, technology, healthcare, finance, manufacturing, supply chain, and professional services. Available positions vary over time.

  • Which Michigan cities have professional job opportunities?question toggle

    Opportunities can be found in Detroit, Grand Rapids, Ann Arbor, Lansing, Kalamazoo, and other Michigan communities. Search by location to find roles that match your preferences.

  • Are Michigan jobs on Ladders vetted?question toggle

    Ladders focuses on vetted professional job opportunities with salaries of $100,000 or more. Check individual listings for details about the employer, role, location, and compensation.

  • Do Michigan jobs offer remote or hybrid work?question toggle

    Some employers may offer remote or hybrid arrangements, while others require on-site work. Review each job listing for its specific work-location expectations.