Explore professional opportunities across Massachusetts with Ladders. Browse vetted jobs paying $100,000 or more, from roles in Boston and Cambridge to opportunities in Worcester, Springfield, and other communities throughout the state. Whether you’re pursuing your next leadership position or advancing your career in a specialized field, discover openings that match your experience and goals.
Massachusetts is home to a diverse economy with employers in technology, healthcare, financial services, education, biotechnology, manufacturing, and professional services. Job availability and compensation vary by employer, role, and experience. Use Ladders to explore current openings and identify opportunities aligned with your skills.
Focus your search on major employment centers such as Boston, Cambridge, and Worcester, or look across the state for roles that fit your preferences. Refine your search by job title, industry, seniority, and other relevant criteria to find opportunities suited to your career direction.
Ladders specializes in vetted professional jobs paying $100,000 or more. Review listings, compare role requirements, and apply to positions that align with your qualifications. Set up a complete profile and keep your resume current to make it easier to pursue your next Massachusetts opportunity.
Senior Director, Patient Reported Outcomes
$222K - $292K *
Elevate patient outcomes by leading global evidence strategies that showcase the value of therapies. Collaborate across functions to drive research programs, influence decision-making, and ensure scie...
2 weeks ago
$150K - $200K *
Lead the charge in delivering complex federal digital services programs, ensuring strategic direction, operational excellence, and strong customer relationships across multidisciplinary teams while ma...
Today
Senior Consultant - Healthcare Compliance
$100K - $125K *
Empower healthcare compliance by enhancing programs, mitigating risks, and driving operational integrity. Collaborate with diverse clients to deliver tailored solutions in a dynamic regulatory landsca...
2 weeks ago
$117K - $160K *
Lead the charge in underwriting E&S commercial property and casualty accounts. Manage risk assessments, develop competitive quotes, and collaborate with carriers to optimize profitability while achiev...
2 days ago
Operations Standards Manager (Remote)
$80K - $95K *
Drive operational excellence by developing and maintaining standards, ensuring consistency across markets, and collaborating with cross-functional teams to enhance processes and documentation for opti...
1 week ago
$150K - $175K *
Shape exceptional user experiences by leading design for a unified legal platform. Drive user-centered solutions through research, collaboration, and design leadership to meet the complex needs of leg...
Reposted 3 weeks ago
Associate Director of Innovation
$204K - $255K *
Grow your career with us by driving innovation in legal services through AI. Collaborate closely with leadership and attorneys to develop transformative solutions that enhance practice efficiency and...
3 weeks ago
Therapy Development Specialist - Northeast Region
$110K - $175K *
Accelerate patient care by optimizing therapy pathways and engaging key stakeholders. Collaborate with healthcare teams to enhance VTE awareness and program development, driving clinical initiatives a...
3 days ago
$85K - $98K *
Contribute to the operational execution of clinical trials, ensuring compliance and efficiency from start-up to close-out. Collaborate with cross-functional teams to track documentation, manage record...
3 weeks ago
Senior Consultant - Data Platforms & Architecture
$103K - $154K *
Unlock advanced data solutions by leveraging Microsoft Azure and Power BI. Collaborate with teams to deliver high-quality analytics and reporting, while enhancing business intelligence capabilities th...
3 days ago
$91K - $112K *
Transform healthcare delivery by engaging with members to create tailored care plans, addressing complex needs, and collaborating with a dedicated team to promote optimal health outcomes and seamless...
1 week ago
Manager, Revenue Cycle Operations
$100K - $130K *
Join a dynamic team to lead and enhance billing and coding operations, ensuring quality and compliance across multiple markets. Drive performance, coach leaders, and collaborate cross-functionally to...
2 weeks ago
Medical Director, Hematology Clinical Development
$210K - $250K *
Lead the charge in overseeing clinical trials, ensuring compliance and integrity while collaborating cross-functionally to deliver high-quality data that supports product development and regulatory su...
Yesterday
Nurse Practitioner/Physician Assistant, Emergency Department
$135K - $173K *
Deliver high-quality emergency care as an Advanced Practice Provider, collaborating with a multidisciplinary team to manage diverse patient needs, perform procedures, and engage in ongoing clinical ed...
1 week ago
Solution Architect - Regulatory (RIM)
$120K - $145K *
Bring your expertise to a senior role driving customer success in Pharmaceutical Regulatory. Lead implementations, manage accounts, and cultivate relationships to ensure long-term client satisfaction...
3 weeks ago
Scientist, In Vivo Cancer Modeling
$110K - $130K *
Drive the development of innovative RNA therapeutics by designing and executing in vivo studies, coordinating with CROs, and providing expertise in pharmacology to enhance therapeutic efficacy and saf...
2 weeks ago
Sr. Solution Architect, Professional Services - Agentic AI
$121K - $132K *
Engage as a key technical leader in enterprise AI/ML architecture, collaborating with clients to design scalable solutions. Drive AI development and deployment, ensuring alignment with business needs...
3 weeks ago
$110K - $130K *
Lead end-to-end client implementations, ensuring timely and impactful project delivery while collaborating across teams to drive exceptional customer experiences and measurable outcomes in a dynamic h...
4 weeks ago
$120K - $150K *
Unlock operational excellence by leading multi-site Ambulatory Surgery Centers. Drive growth strategies, optimize performance, and foster strong partnerships with physician leaders while managing sign...
Reposted yesterday
Director, Public Safety Operations
$130K - $150K *
Champion public safety operations across North America, leading program directors to ensure effective training, deployment, and customer satisfaction while aligning resources and operational prioritie...
2 days ago
Associate Director, Regulatory Project Management
$150K - $214K *
Lead complex global regulatory project management activities, ensuring alignment across functions and successful submission milestones. Drive operational excellence and best practices to support a gro...
2 weeks ago
Business Unit Leader, Early Intervention
$178K - $307K *
Join us as a Business Unit Leader to drive national sales strategies and lead the Early Intervention team. Shape the future of Osteoarthritis treatment through impactful leadership, market access stra...
Reposted 4 days ago
Senior Engineer, Back-End (Security Controls)
$199K - $270K *
Tackle the complexities of backend engineering by developing robust API integrations, building ETL pipelines, and collaborating with cross-functional teams to enhance system reliability and performanc...
Reposted 4 weeks ago
Solutions Integration Engineer IV
$105K - $160K *
Take ownership of B2B integrations as a key technical leader, collaborating across teams to deliver effective solutions that drive customer success and evolve with innovative IoT technology. Expect a...
Reposted 3 weeks ago
Senior Director, Head of Enterprise Clinical AI & Technology - Remote - The Cigna Group
$193K - $322K *
Join a team that leads the charge in advancing clinical AI and technology, shaping solutions that enhance clinician experience and patient outcomes while navigating complex healthcare environments...
4 weeks ago
What types of $100,000+ jobs can I find in Massachusetts?
Listings may include professional and leadership roles across fields such as technology, healthcare, finance, biotechnology, education, manufacturing, and business services. Available positions change, so browse current listings for the latest opportunities.
Where can I find professional jobs in Massachusetts?
Search across the state, including major employment centers such as Boston, Cambridge, and Worcester. You can also use location filters to explore roles in other Massachusetts communities.
Are the Massachusetts jobs on Ladders vetted?
Ladders features vetted professional job listings paying $100,000 or more. Review each listing for details about the employer, responsibilities, qualifications, and compensation.
How can I find a Massachusetts job that matches my experience?
Use filters such as location, job title, industry, and seniority to narrow your search. Keep your resume current and compare each listing’s requirements with your skills and career goals.