Find $100K+ Jobs in Massachusetts

Explore professional opportunities across Massachusetts with Ladders. Browse vetted jobs paying $100,000 or more, from roles in Boston and Cambridge to opportunities in Worcester, Springfield, and other communities throughout the state. Whether you’re pursuing your next leadership position or advancing your career in a specialized field, discover openings that match your experience and goals.

Explore Massachusetts Career Opportunities

Massachusetts is home to a diverse economy with employers in technology, healthcare, financial services, education, biotechnology, manufacturing, and professional services. Job availability and compensation vary by employer, role, and experience. Use Ladders to explore current openings and identify opportunities aligned with your skills.

Search by Location and Specialty

Focus your search on major employment centers such as Boston, Cambridge, and Worcester, or look across the state for roles that fit your preferences. Refine your search by job title, industry, seniority, and other relevant criteria to find opportunities suited to your career direction.

Advance Your Career with Ladders

Ladders specializes in vetted professional jobs paying $100,000 or more. Review listings, compare role requirements, and apply to positions that align with your qualifications. Set up a complete profile and keep your resume current to make it easier to pursue your next Massachusetts opportunity.

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$142K - $154K *

Join a dynamic team to enhance defense systems through human factors engineering. Leverage your expertise to evaluate designs, improve usability, and ensure compliance with military standards while co...

1 week ago

  •   5 - 7 years exp.  •   Aerospace & Defense

$120K - $220K *

Pioneer your career as a Medical Director, leading a new veterinary practice with full ownership opportunities. Enjoy medical autonomy, state-of-the-art facilities, and the chance to shape your clinic...

3 days ago

  •   Less than 5 years exp.  •   Healthcare

$230K - $250K *

Elevate market research and competitive intelligence initiatives to drive brand strategy. Collaborate with cross-functional teams to uncover insights, manage research projects, and deliver actionable...

1 week ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$115K - $165K *

Tackle challenges by ensuring operational excellence through strategic planning, effective resource management, and continuous improvement, while leading a team to meet commitments in a dynamic startu...

United StatesRemote

Reposted 4 days ago

  •   5 - 7 years exp.  •   Finance & Insurance

$64K - $162K *

Drive innovative strategies to enhance visibility across Generative Engine Optimization and AI search platforms, supporting higher education clients and professional education products through data-dr...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Education, Government & Non-Profit

$100K *

Join a team that's dedicated to enhancing resident care through comprehensive assessments, personalized care plans, and effective staff management, ensuring compliance with regulations while fostering...

Today

  •   Less than 5 years exp.  •   Real Estate & Construction

$100K *

Unlock potential by leading resident care initiatives, assessing health needs, and ensuring compliance with regulations. Collaborate with staff and families to enhance quality of life for residents in...

Today

  •   Less than 5 years exp.  •   Real Estate & Construction

$233K - $350K *

Drive the strategic direction and execution of clinical programs, ensuring timely, cost-effective delivery. Collaborate with cross-functional teams to enhance drug development efforts and promote qual...

3 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$100K - $120K *

Empower exceptional end-of-life care by leading clinical services, ensuring high-quality patient-centered practices, and fostering a collaborative team environment focused on operational efficiency an...

1 week ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$180K - $220K *

Drive operational excellence and growth across a network of clinical research sites, ensuring high performance, strategic alignment, and exceptional experiences for all stakeholders. Lead a diverse te...

2 weeks ago

  •   11 - 15 years exp.  •   Healthcare

$118K - $196K *

Transform client outcomes through innovative problem-solving and project management in power systems consulting. Engage in impactful research and data analysis to enhance climate resilience and sustai...

RemoteRemote

Reposted 4 days ago

  •   5 - 7 years exp.  •   Business Services

$118K - $196K *

Empower impactful change in energy consulting. Utilize data analysis and problem-solving skills to enhance climate resilience, sustainability, and grid modernization while collaborating with clients a...

Reposted 4 days ago

  •   5 - 7 years exp.  •   Business Services

$175K - $210K *

Elevate your career by owning the sales cycle for major employers, building strategic partnerships, and driving innovative health programs that shape enterprise success and market presence...

RemoteRemote

3 weeks ago

  •   8 - 10 years exp.  •   Healthcare

$250K - $275K *

Lead innovative solution architecture efforts by collaborating across teams to create scalable, client-focused strategies that drive successful business outcomes and mentor others in technical rigor a...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$83K - $99K *

Enhance lives by assisting older adults with daily activities, mobility, and personal tasks. Collaborate with caregivers and families, ensuring quality care and ethical resolutions, while experiencing...

Reposted 2 weeks ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$125K - $155K *

Optimize antibody discovery and engineering through innovative phage and yeast display technologies, driving high-quality lead development and cross-functional collaboration in a dynamic research envi...

2 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$180K - $215K *

Transform your career by leading regional sales efforts, driving product launch success, and building high-performing teams. Collaborate cross-functionally to achieve sales goals and foster strong cus...

United StatesRemote

2 days ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$80K - $117K *

Empower your career by leading innovative neurological care operations. Drive strategic initiatives, enhance patient experiences, and develop high-performing teams in a collaborative environment dedic...

2 weeks ago

  •   5 - 7 years exp.  •   Hospitals & Medical Centers

$110K - $130K *

Transform clinical operations by leading a dynamic team, ensuring high-quality trial management, and driving innovation through technology and AI solutions. Your strategic oversight will enhance perfo...

RemoteRemote

1 week ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$170K - $235K *

Drive the design and implementation of backend services to enhance customer experiences across NodeZero’s licensing, provisioning, and admin systems. Lead efforts to ensure accuracy, scalability, and...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$100K - $120K *

Accelerate progress at our walk-in center by leading a dedicated team of clinicians. Oversee patient care, mentor new providers, and ensure quality treatment in a collaborative environment focused on...

4 weeks ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$176K - $230K *

Lead the charge in transforming healthcare through data-driven solutions. As a Senior Data Scientist, you'll spearhead projects that enhance patient outcomes, leveraging your expertise to align data s...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$115K - $125K *

Join a team that's focused on building and enhancing relationships with large managed care accounts. Utilize your expertise in account management to drive customer satisfaction, explore upselling oppo...

United StatesRemote

Reposted 2 days ago

  •   5 - 7 years exp.  •   Staffing

$306K - $343K *

Join our team to lead pharmacovigilance efforts, ensuring safety oversight for investigational products, aligning strategies with regulatory requirements, and collaborating across teams to uphold part...

Waltham, MARemote

4 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$306K - $343K *

Join a team that's shaping product safety strategies and leading pharmacovigilance efforts. You will oversee safety processes, ensuring compliance and participant safety while contributing to innovati...

4 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

Frequently Asked Questions (FAQ)

  • What types of $100,000+ jobs can I find in Massachusetts?question toggle

    Listings may include professional and leadership roles across fields such as technology, healthcare, finance, biotechnology, education, manufacturing, and business services. Available positions change, so browse current listings for the latest opportunities.

  • Where can I find professional jobs in Massachusetts?question toggle

    Search across the state, including major employment centers such as Boston, Cambridge, and Worcester. You can also use location filters to explore roles in other Massachusetts communities.

  • Are the Massachusetts jobs on Ladders vetted?question toggle

    Ladders features vetted professional job listings paying $100,000 or more. Review each listing for details about the employer, responsibilities, qualifications, and compensation.

  • How can I find a Massachusetts job that matches my experience?question toggle

    Use filters such as location, job title, industry, and seniority to narrow your search. Keep your resume current and compare each listing’s requirements with your skills and career goals.