Explore professional opportunities across Massachusetts with Ladders. Browse vetted jobs paying $100,000 or more, from roles in Boston and Cambridge to opportunities in Worcester, Springfield, and other communities throughout the state. Whether you’re pursuing your next leadership position or advancing your career in a specialized field, discover openings that match your experience and goals.
Massachusetts is home to a diverse economy with employers in technology, healthcare, financial services, education, biotechnology, manufacturing, and professional services. Job availability and compensation vary by employer, role, and experience. Use Ladders to explore current openings and identify opportunities aligned with your skills.
Focus your search on major employment centers such as Boston, Cambridge, and Worcester, or look across the state for roles that fit your preferences. Refine your search by job title, industry, seniority, and other relevant criteria to find opportunities suited to your career direction.
Ladders specializes in vetted professional jobs paying $100,000 or more. Review listings, compare role requirements, and apply to positions that align with your qualifications. Set up a complete profile and keep your resume current to make it easier to pursue your next Massachusetts opportunity.
Senior Computer Systems Validation Engineer
$110K - $130K *
Champion validation excellence by ensuring compliance and data integrity for computerized systems in a regulated environment. Collaborate with cross-functional teams to develop strategies and oversee...
1 week ago
Senior Computer Systems Validation Engineer
$110K - $130K *
Transform validation processes by ensuring compliance and data integrity for computerized systems in a regulated environment. Collaborate with teams to develop strategies and mentor junior members whi...
1 week ago
Director, Clinical Research and Cancer Center Advisory Services
$175K - $200K *
Drive impactful change in healthcare consulting by leveraging your expertise in clinical operations and research administration. Collaborate with executive leaders to solve complex challenges and fost...
2 weeks ago
$90K - $110K *
Transform your career by managing comprehensive Property Accounting and Finance operations across diverse portfolios, ensuring compliance and operational excellence while collaborating with key stakeh...
4 weeks ago
Clinical Lead Early Clinical and Experimental Therapeutics
$206K - $343K *
Unlock potential by leading innovative clinical developments from preclinical to early clinical stages. Collaborate across disciplines to ensure successful trial execution and actionable insights, mak...
Reposted 1 week ago
$135K - $160K *
Lead innovative sales strategies to drive new business in healthcare technology, focusing on clinical data exchange and interoperability. Engage with C-suite executives to close complex deals and enha...
Yesterday
$95K - $115K *
Drive innovative ServiceNow solutions in a dynamic, collaborative environment, ensuring effective development, integration, and deployment for government clients while enhancing platform capabilities...
3 weeks ago
Senior Instructional System Designer
$95K - $115K *
Transform the learning landscape by leading the design and development of innovative educational materials. You'll engage diverse teams to create immersive, high-quality training experiences using cut...
Reposted 1 week ago
Application Analyst III - Epic Healthy Planet - Hybrid (Remote Considered) - 26-110
$109K - $144K *
Lead the charge in optimizing Epic Population Health applications, ensuring effective support, administration, and collaboration with multi-disciplinary teams to enhance patient engagement and improve...
4 weeks ago
$103K - $123K *
Drive growth by managing a sales territory, building relationships, and generating premium. Leverage existing partnerships while prospecting new agencies to achieve targets and expand market presence...
2 days ago
$80K - $95K *
Unlock potential by leading high-throughput antibody discovery and development in a collaborative environment. Utilize advanced techniques in protein biochemistry, automation, and molecular biology, w...
Reposted 1 week ago
Senior Product Designer - Benefits Servicing
$86K - $118K *
Design and deliver engaging user experiences for medical benefits, leveraging user-centered principles and collaboration to enhance member satisfaction and streamline healthcare navigation. Shape impa...
Reposted 1 week ago
Regional Sales Director - Northwest
$180K - $215K *
Unlock regional growth by leading a high-performing sales team, executing launch strategies, and fostering key customer relationships in a dynamic, fast-paced environment. Drive performance and ensure...
2 days ago
Early Intervention Occupational Therapist-Full Time
$72K - $89K *
Join a dynamic Early Intervention team to deliver impactful OT services for children (birth-3 years) with developmental delays. Collaborate with families and professionals to foster growth in natural...
Today
Principal IT Analyst - Veeva RIM
$121K - $161K *
Transform your career by leading the design and implementation of Veeva Vault RIM, ensuring optimal performance and compliance while collaborating with cross-functional teams to enhance user experienc...
2 weeks ago
Neuromuscular Account Manager - Mid-Atlantic
$155K - $210K *
Drive success by championing patient needs and executing strategic account plans. Leverage clinical expertise and business acumen to exceed sales goals while fostering relationships with key stakehold...
Today
$100K - $120K *
Join a dynamic team where you'll take ownership of key Corporate Performance Management projects, executing tasks from build to testing, while collaborating with clients and delivering high-quality wo...
Reposted yesterday
Urgent Care Nurse Practitioner/Physician Assistant
$127K - $160K *
Advance your career by joining a dynamic team in urgent care, providing essential services across multiple locations. Enjoy a supportive environment with strong collaboration and a predictable schedul...
3 days ago
Professional, Prog Lead, PenTesting Svcs
$94K - $151K *
Innovate your career by leading penetration testing services programs that enhance the security of medical devices and applications, ensuring safety and compliance through robust testing methodologies...
Reposted 4 days ago
Manager of Respiratory Therapy
$85K - $100K *
Engage in operational and clinical oversight to enhance Respiratory services, ensuring high-quality, patient-centered care across multiple locations. Drive continuous improvement while fostering a col...
2 weeks ago
Senior Forward Deployed Engineer
$120K - $145K *
Shape the future of customer relationships by driving value and retention for large organizations, collaborating closely with sales and product teams to ensure success and growth through data-driven i...
4 weeks ago
Marketing Manager, Campaigns & Messaging- Spine
$102K - $177K *
Lead the charge in developing innovative spine marketing strategies that drive growth and enhance patient care. Collaborate with cross-functional teams to create compelling campaigns that resonate wit...
3 days ago
Marketing Manager, Campaigns & Messaging- Spine
$102K - $177K *
Pioneer innovative digital marketing strategies to enhance spine product campaigns. Collaborate with cross-functional teams to develop compelling messaging and content that drives engagement and suppo...
3 days ago
$110K - $145K *
Unlock potential by managing and optimizing IT operations across platforms and applications. Collaborate with teams to ensure security, reliability, and efficiency while developing scalable processes...
Today
$110K - $145K *
Join a team that's dedicated to maintaining secure, reliable IT operations. You'll manage platforms, troubleshoot applications, and enhance workflows, ensuring seamless support for internal teams whil...
Today
What types of $100,000+ jobs can I find in Massachusetts?
Listings may include professional and leadership roles across fields such as technology, healthcare, finance, biotechnology, education, manufacturing, and business services. Available positions change, so browse current listings for the latest opportunities.
Where can I find professional jobs in Massachusetts?
Search across the state, including major employment centers such as Boston, Cambridge, and Worcester. You can also use location filters to explore roles in other Massachusetts communities.
Are the Massachusetts jobs on Ladders vetted?
Ladders features vetted professional job listings paying $100,000 or more. Review each listing for details about the employer, responsibilities, qualifications, and compensation.
How can I find a Massachusetts job that matches my experience?
Use filters such as location, job title, industry, and seniority to narrow your search. Keep your resume current and compare each listing’s requirements with your skills and career goals.