Find $100K+ Jobs in Massachusetts

Explore professional opportunities across Massachusetts with Ladders. Browse vetted jobs paying $100,000 or more, from roles in Boston and Cambridge to opportunities in Worcester, Springfield, and other communities throughout the state. Whether you’re pursuing your next leadership position or advancing your career in a specialized field, discover openings that match your experience and goals.

Explore Massachusetts Career Opportunities

Massachusetts is home to a diverse economy with employers in technology, healthcare, financial services, education, biotechnology, manufacturing, and professional services. Job availability and compensation vary by employer, role, and experience. Use Ladders to explore current openings and identify opportunities aligned with your skills.

Search by Location and Specialty

Focus your search on major employment centers such as Boston, Cambridge, and Worcester, or look across the state for roles that fit your preferences. Refine your search by job title, industry, seniority, and other relevant criteria to find opportunities suited to your career direction.

Advance Your Career with Ladders

Ladders specializes in vetted professional jobs paying $100,000 or more. Review listings, compare role requirements, and apply to positions that align with your qualifications. Set up a complete profile and keep your resume current to make it easier to pursue your next Massachusetts opportunity.

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$116K *

Drive impactful site activation strategies, collaborating with cross-functional teams to ensure timely delivery of clinical projects while enhancing communication and mitigating risks throughout the p...

United StatesRemote

Yesterday

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$206K - $257K *

Drive your career by leading statistical strategy in clinical trials, overseeing design, analysis, and reporting to ensure high-quality outcomes. Collaborate with cross-functional teams and advance to...

4 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$75K - $100K *

Champion mental health by joining our dynamic team of licensed therapists. Enjoy flexible scheduling, competitive compensation, and a supportive environment that prioritizes your professional growth a...

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$75K - $100K *

Empower individuals by providing therapeutic support in a flexible, hybrid environment. Collaborate with a diverse team to enhance mental health services, ensuring quality care and professional growth...

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$162K - $271K *

Join a dynamic team as a strategic insights partner, driving US forecasting, market research, and launch planning for innovative thoracic therapies. Collaborate cross-functionally to shape strategies...

2 days ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$108K - $162K *

Deliver exceptional customer service by managing maintenance operations and support activities. Collaborate with teams to ensure timely resolution of issues while leading talent development and execut...

RemoteRemote

Today

  •   5 - 7 years exp.  •   Business Services

$104K - $156K *

Unlock your potential as a Solutions Engineer, driving sales success by leveraging technical expertise to address customer challenges and deliver F5 solutions. Collaborate with sales teams to achieve...

RemoteRemote

6 days ago

  •   5 - 7 years exp.  •   Information Technology

$134K - $205K *

Elevate your career by leading a dynamic communications team, ensuring high-quality content that reflects the firm's voice. Collaborate with attorneys and leadership to produce compelling communicatio...

1 week ago

  •   8 - 10 years exp.  •   Legal & Accounting

$110K - $130K *

Transform early phase clinical trials by leading design, execution, and oversight. Collaborate with cross-functional teams to ensure compliance and data integrity while managing project performance an...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$240K - $280K *

Lead the execution of medical strategies for an Immunology asset, ensuring ethical and scientific standards in pre-launch and launch activities. Collaborate across functions to support clinical studie...

4 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$100K - $120K *

Support clinical studies by assisting teams with tasks like medical monitoring and protocol management. Collaborate across functions and engage with stakeholders to ensure successful trial outcomes wh...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$240K - $280K *

Advance the global medical strategy and execution for an Immunology asset, leading medical affairs activities and ensuring high standards in scientific communication and training while collaborating w...

Boston, MARemote

4 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$71K - $97K *

Inspire change by providing essential social work support to patients and families, addressing psychosocial challenges in a collaborative healthcare environment. Your expertise will enhance patient ca...

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$60K - $107K *

Champion the management of clinical research projects, overseeing trials from inception to completion. Lead and train staff, liaise with stakeholders, and ensure compliance with protocols while enhanc...

2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$204K - $255K *

Transform global medical strategy for rheumatology, leading evidence generation and stakeholder engagement. Drive launch readiness for IgG4-RD and support pipeline programs, leveraging deep expertise...

2 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$77K - $129K *

Join a team that's dedicated to enhancing healthcare communication. Support the implementation and administration of a hands-free communication solution, training clinical staff and ensuring seamless...

2 days ago

  •   Less than 5 years exp.  •   Healthcare

$160K - $200K *

Optimize the future of oncology by driving product strategy, engaging key opinion leaders, and translating complex needs into innovative healthcare solutions that improve patient care and clinician ex...

United StatesRemote

1 month ago

  •   8 - 10 years exp.  •   Healthcare

$80K - $90K *

Shape and execute innovative social media strategies to enhance brand storytelling, drive engagement, and support corporate communications initiatives while collaborating with diverse teams to achieve...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Business Services

$116K - $157K *

Grow your career with our FP&A Systems team, designing innovative EPM solutions and enhancing financial planning processes. Collaborate with various stakeholders to optimize efficiency and ensure data...

United StatesRemote

Reposted 2 weeks ago

  •   Less than 5 years exp.  •   Legal & Accounting

$145K - $175K *

Deliver innovative datacenter, cloud, and network solutions by leading architecture design, client engagement, and technical governance. Collaborate with cross-functional teams to shape complex infras...

United StatesRemote

Today

  •   8 - 10 years exp.  •   Information Technology

$101K - $119K *

Unlock potential by driving strategic engagement marketing initiatives that enhance client and member interactions. Collaborate cross-functionally to develop effective communication strategies and mea...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$110K - $130K *

Join a team that champions proactive advocacy within healthcare policy. Lead government affairs initiatives, engage with federal agencies, and strengthen strategic partnerships to ensure impactful rep...

United StatesRemote

Reposted 3 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$245K - $325K *

Lead the charge in transforming enterprise business applications, driving strategy and governance for core systems like SAP and Veeva. This hands-on role requires strategic vision and technical expert...

2 weeks ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$80K - $117K *

Join a team that's shaping the future of cardiovascular care! In this leadership role, you'll oversee clinical operations, enhance patient experiences, and drive strategic initiatives across multiple...

1 week ago

  •   5 - 7 years exp.  •   Hospitals & Medical Centers

$135K - $173K *

Empower patient care by assessing and managing diverse populations, performing diagnostic interventions, and developing tailored care plans. Collaborate with healthcare teams to ensure high-quality ou...

6 days ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

Frequently Asked Questions (FAQ)

  • What types of $100,000+ jobs can I find in Massachusetts?question toggle

    Listings may include professional and leadership roles across fields such as technology, healthcare, finance, biotechnology, education, manufacturing, and business services. Available positions change, so browse current listings for the latest opportunities.

  • Where can I find professional jobs in Massachusetts?question toggle

    Search across the state, including major employment centers such as Boston, Cambridge, and Worcester. You can also use location filters to explore roles in other Massachusetts communities.

  • Are the Massachusetts jobs on Ladders vetted?question toggle

    Ladders features vetted professional job listings paying $100,000 or more. Review each listing for details about the employer, responsibilities, qualifications, and compensation.

  • How can I find a Massachusetts job that matches my experience?question toggle

    Use filters such as location, job title, industry, and seniority to narrow your search. Keep your resume current and compare each listing’s requirements with your skills and career goals.