Find $100K+ Jobs in Massachusetts

Explore professional opportunities across Massachusetts with Ladders. Browse vetted jobs paying $100,000 or more, from roles in Boston and Cambridge to opportunities in Worcester, Springfield, and other communities throughout the state. Whether you’re pursuing your next leadership position or advancing your career in a specialized field, discover openings that match your experience and goals.

Explore Massachusetts Career Opportunities

Massachusetts is home to a diverse economy with employers in technology, healthcare, financial services, education, biotechnology, manufacturing, and professional services. Job availability and compensation vary by employer, role, and experience. Use Ladders to explore current openings and identify opportunities aligned with your skills.

Search by Location and Specialty

Focus your search on major employment centers such as Boston, Cambridge, and Worcester, or look across the state for roles that fit your preferences. Refine your search by job title, industry, seniority, and other relevant criteria to find opportunities suited to your career direction.

Advance Your Career with Ladders

Ladders specializes in vetted professional jobs paying $100,000 or more. Review listings, compare role requirements, and apply to positions that align with your qualifications. Set up a complete profile and keep your resume current to make it easier to pursue your next Massachusetts opportunity.

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$141K - $172K *

Tackle operational challenges by leading large-scale project management initiatives, driving efficiency, and fostering client relationships to optimize growth and sustainability in critical infrastruc...

United StatesRemote

Reposted 4 weeks ago

  •   11 - 15 years exp.  •   Technical Services

$180K - $200K *

Empower innovation by leading lab technologies that transform scientific data into actionable insights. Drive software development, cloud architecture, and bioinformatics for research teams while ment...

1 month ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$122K *

Elevate your career by managing global projects in Neuroscience, ensuring compliance, budget adherence, and successful collaboration across cross-functional teams to drive milestone achievement and en...

United StatesRemote

Reposted 2 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$109K - $174K *

Lead the charge in advancing high-throughput screening platforms for viral and bacterial antigens, driving innovative experimental design and collaboration with computational teams to optimize antigen...

2 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$130K - $185K *

Shape the future of video content at a tech-driven company. Lead the charge in creating, managing, and delivering high-quality video assets for a developer audience, while collaborating with cross-fun...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Information Technology

$62K - $111K *

Serve as a clinical expert to assess and counsel patients and families, fostering positive discharge outcomes through collaborative care planning and resource identification while adhering to high sta...

Reposted today

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$68K - $116K *

Help us provide exceptional patient care by coordinating and delivering hemodialysis treatments, assessing patient needs, and collaborating with the healthcare team to enhance outcomes in a dynamic he...

Reposted 3 days ago

  •   Less than 5 years exp.  •   Healthcare

$68K - $116K *

Grow your nursing career providing essential care in a dynamic outpatient setting. Champion patient outcomes through assessment, education, and collaboration as a vital member of the End Stage Kidney...

Reposted 3 days ago

  •   Less than 5 years exp.  •   Healthcare

$64K - $108K *

Innovate patient care as an Outpatient RN, coordinating treatment and education for ESKD patients. Collaborate with a healthcare team to enhance outcomes and ensure safe hemodialysis delivery while ad...

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$68K - $116K *

Unlock potential by delivering compassionate care in hemodialysis, coordinating patient treatment plans, and providing education in a dynamic healthcare environment. Collaborate with a multidisciplina...

Reposted 1 week ago

  •   Less than 5 years exp.  •   Healthcare

$81K - $116K *

Transform patient care as an Outpatient RN, coordinating and delivering high-quality nursing services. Collaborate with a dedicated healthcare team to enhance outcomes for patients with End Stage Kidn...

2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$81K - $116K *

Explore a rewarding nursing career in outpatient care, providing essential support and coordination for patients undergoing hemodialysis. Collaborate with a dedicated healthcare team to enhance patien...

2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$81K - $116K *

Provide clinically competent care for patients in hemodialysis, coordinating assessments, interventions, and evaluations. Collaborate with healthcare teams to enhance patient outcomes and participate...

2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$81K - $116K *

Unlock potential by providing compassionate, clinically competent care to patients in a dynamic hemodialysis setting. Collaborate with a dedicated healthcare team to enhance patient outcomes through a...

2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$81K - $116K *

Elevate patient care as a Registered Nurse in a dynamic float role, providing essential hemodialysis treatment and support. Collaborate with a dedicated healthcare team to enhance patient outcomes and...

2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$81K - $116K *

Elevate your nursing career by providing essential patient care in a dynamic outpatient setting. Collaborate with a dedicated healthcare team to enhance patient outcomes through assessment, education...

Reposted 3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$68K - $116K *

Pioneer in delivering comprehensive patient care by coordinating assessments, interventions, and education for chronic kidney disease patients while collaborating with an interdisciplinary team to enh...

Reposted 3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$80K - $95K *

Help us enhance federal human capital operations through independent analysis, strategic recommendations, and effective program delivery. Collaborate on data-driven insights to improve efficiency and...

United StatesRemote

Reposted 5 days ago

  •   Less than 5 years exp.  •   Healthcare

$125K - $220K *

Drive security excellence by leading a dynamic team to enhance our cloud platform's security posture. Collaborate across departments to ensure compliance, resilience, and customer trust while fosterin...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$120K - $150K *

Lead the charge in advancing clinical revenue cycle management initiatives, ensuring accurate documentation and coding while driving performance improvements across diverse stakeholders to enhance rev...

United StatesRemote

Reposted 4 weeks ago

  •   8 - 10 years exp.  •   Healthcare

$80K - $95K *

Optimize IT operations by managing day-to-day support for macOS and Windows environments, ensuring seamless onboarding/offboarding, and administering SaaS platforms while enhancing user experience and...

United StatesRemote

2 days ago

  •   Less than 5 years exp.  •   Information Technology

$90K - $105K *

Optimize healthcare support by serving as the primary contact for clinical application issues. Collaborate with clinicians and IT teams to troubleshoot, educate, and resolve technical challenges, ensu...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Staffing

$108K - $130K *

Drive program delivery across multiple products, ensuring timely outcomes by managing risks, dependencies, and stakeholder priorities. Collaborate cross-functionally to maintain accurate project data...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$102K - $177K *

Elevate your career by joining a dynamic cybersecurity team dedicated to ensuring product security in innovative medical devices, where you'll make impactful contributions throughout development cycle...

Reposted 1 week ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$95K - $100K *

Empower individuals by delivering expert speech-language therapy in diverse home settings. Collaborate with healthcare teams to evaluate and treat communication disorders, enhancing patient quality of...

6 days ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

Frequently Asked Questions (FAQ)

  • What types of $100,000+ jobs can I find in Massachusetts?question toggle

    Listings may include professional and leadership roles across fields such as technology, healthcare, finance, biotechnology, education, manufacturing, and business services. Available positions change, so browse current listings for the latest opportunities.

  • Where can I find professional jobs in Massachusetts?question toggle

    Search across the state, including major employment centers such as Boston, Cambridge, and Worcester. You can also use location filters to explore roles in other Massachusetts communities.

  • Are the Massachusetts jobs on Ladders vetted?question toggle

    Ladders features vetted professional job listings paying $100,000 or more. Review each listing for details about the employer, responsibilities, qualifications, and compensation.

  • How can I find a Massachusetts job that matches my experience?question toggle

    Use filters such as location, job title, industry, and seniority to narrow your search. Keep your resume current and compare each listing’s requirements with your skills and career goals.