Find $100K+ Jobs in Massachusetts

Explore professional opportunities across Massachusetts with Ladders. Browse vetted jobs paying $100,000 or more, from roles in Boston and Cambridge to opportunities in Worcester, Springfield, and other communities throughout the state. Whether you’re pursuing your next leadership position or advancing your career in a specialized field, discover openings that match your experience and goals.

Explore Massachusetts Career Opportunities

Massachusetts is home to a diverse economy with employers in technology, healthcare, financial services, education, biotechnology, manufacturing, and professional services. Job availability and compensation vary by employer, role, and experience. Use Ladders to explore current openings and identify opportunities aligned with your skills.

Search by Location and Specialty

Focus your search on major employment centers such as Boston, Cambridge, and Worcester, or look across the state for roles that fit your preferences. Refine your search by job title, industry, seniority, and other relevant criteria to find opportunities suited to your career direction.

Advance Your Career with Ladders

Ladders specializes in vetted professional jobs paying $100,000 or more. Review listings, compare role requirements, and apply to positions that align with your qualifications. Set up a complete profile and keep your resume current to make it easier to pursue your next Massachusetts opportunity.

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$300K - $383K *

Lead and innovate within a dynamic health division, overseeing research projects and driving strategic initiatives to enhance organizational performance and impact in health policy and services...

4 days ago

  •   8 - 10 years exp.  •   Education, Government & Non-Profit

$118K - $172K *

Join a team that's dedicated to delivering exceptional patient care by directing and coordinating nursing services, ensuring staff development, and fostering a safe, positive environment for both pati...

6 days ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$96K - $207K *

Lead the charge in managing complex credit liquidations and rehabilitations. Collaborate with Portfolio Managers to optimize returns while ensuring compliance and risk management, fostering a positive...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Finance & Insurance

$95K - $115K *

Join a dynamic healthcare team to elevate patient care across surgical and clinical settings, collaborating closely with physicians as a first assistant in the OR, managing pre and post-operative care...

4 weeks ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$293K - $358K *

Champion clinical trial execution in oncology, ensuring patient safety and protocol adherence while collaborating within a high-caliber cross-functional team and shaping future drug development strate...

Reposted 3 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$99K - $119K *

Execute advanced diagnostic CT procedures with minimal supervision, managing diverse responsibilities while ensuring patient safety and effective communication in a collaborative healthcare environmen...

3 weeks ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$80K - $95K *

Champion the development and execution of mission command training, mentoring unit leaders to enhance operational proficiency across various training domains. Collaborate with senior staff to ensure e...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Aerospace & Defense

$80K - $95K *

Join a team that's dedicated to providing comprehensive care for patients with TBI and neurological disorders. Leverage your expertise in an interdisciplinary setting to enhance patient outcomes and s...

2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$274K - $371K *

Elevate patient care through innovative clinical strategies in obesity and cardiometabolic development. Collaborate across teams to design and implement late-phase studies, ensuring alignment with glo...

United StatesRemote

Reposted 4 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$260K - $292K *

Champion strategic leadership in new product planning and commercialization, collaborating across teams to assess market opportunities and define product strategies that drive long-term growth and suc...

2 weeks ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$88K - $95K *

Drive operational excellence by leading projects across teams, enhancing efficiency, managing stakeholders, and ensuring timely delivery. Collaborate within a dynamic environment dedicated to improvin...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$163K - $186K *

Transform clinical research by leading global early phase trials, ensuring compliance and optimizing strategies. Collaborate with cross-functional teams to drive study success and enhance patient outc...

2 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$130K - $170K *

Partner with us to enhance consultant relationships in healthcare. Drive business growth by cultivating partnerships, optimizing engagement strategies, and aligning internal teams to effectively posit...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$176K - $208K *

Drive strategic market forecasting for Neurology, collaborating across functions to inform product plans and expectations. Lead complex revenue models, ensuring alignment with stakeholders and adaptin...

1 week ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$83K - $141K *

Drive risk management excellence by executing control test plans and enhancing testing practices across business units. Collaborate with stakeholders to identify trends and solutions, ensuring complia...

1 week ago

  •   5 - 7 years exp.  •   Finance & Insurance

$307K - $380K *

Lead the charge in shaping intellectual property strategy, managing complex IP matters, and collaborating with R&D teams to drive innovation and protect assets. Serve as a strategic partner and adviso...

2 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$160K - $200K *

Join a team that provides essential medical leadership and care within a substance use treatment program, overseeing quality standards, staff supervision, and direct client medical services to ensure...

3 weeks ago

  •   Less than 5 years exp.  •   Food & Beverages

$100K - $120K *

Unlock potential by collaborating across teams to drive data integrity and safety in oncology clinical studies while developing comprehensive medical review plans and managing project deliverables...

RemoteRemote

Reposted 2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$140K - $190K *

Lead the charge in driving business excellence initiatives across Global Patient Safety. Collaborate with cross-functional teams to enhance project management, governance, and operational effectivenes...

United StatesRemote

Reposted 2 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$110K *

Join a team that's dedicated to delivering empathetic care while performing laser hair removal treatments across the country. As a Traveling Registered Nurse, you'll ensure client comfort and satisfac...

4 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$85K - $100K *

Shape your career by optimizing Workday solutions across Benefits, Compensation, and Reporting. Collaborate with HR and IT to enhance system functionality, troubleshoot issues, and drive continuous im...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Business Services

$73K - $125K *

Unlock potential by conducting in-depth policy analysis and quantitative research to support environmental and public health initiatives. Collaborate with multidisciplinary teams to inform regulatory...

2 weeks ago

  •   Less than 5 years exp.  •   Business Services

$73K - $125K *

Empower your career by providing critical analysis and consulting for environmental and public health programs. Collaborate with multidisciplinary teams to develop evidence-based solutions and support...

3 weeks ago

  •   Less than 5 years exp.  •   Business Services

$130K - $150K *

Elevate your career by designing and optimizing hybrid infrastructure platforms. Collaborate with cross-functional teams to enhance automation, governance, and operational excellence, driving moderniz...

2 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$95K - $115K *

Transform clinical quality by supporting training initiatives, monitoring clinician performance, and ensuring compliance with quality standards for successful operational processes and clinician suppo...

United StatesRemote

Reposted yesterday

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

Frequently Asked Questions (FAQ)

  • What types of $100,000+ jobs can I find in Massachusetts?question toggle

    Listings may include professional and leadership roles across fields such as technology, healthcare, finance, biotechnology, education, manufacturing, and business services. Available positions change, so browse current listings for the latest opportunities.

  • Where can I find professional jobs in Massachusetts?question toggle

    Search across the state, including major employment centers such as Boston, Cambridge, and Worcester. You can also use location filters to explore roles in other Massachusetts communities.

  • Are the Massachusetts jobs on Ladders vetted?question toggle

    Ladders features vetted professional job listings paying $100,000 or more. Review each listing for details about the employer, responsibilities, qualifications, and compensation.

  • How can I find a Massachusetts job that matches my experience?question toggle

    Use filters such as location, job title, industry, and seniority to narrow your search. Keep your resume current and compare each listing’s requirements with your skills and career goals.