Find $100K+ Jobs in Massachusetts

Explore professional opportunities across Massachusetts with Ladders. Browse vetted jobs paying $100,000 or more, from roles in Boston and Cambridge to opportunities in Worcester, Springfield, and other communities throughout the state. Whether you’re pursuing your next leadership position or advancing your career in a specialized field, discover openings that match your experience and goals.

Explore Massachusetts Career Opportunities

Massachusetts is home to a diverse economy with employers in technology, healthcare, financial services, education, biotechnology, manufacturing, and professional services. Job availability and compensation vary by employer, role, and experience. Use Ladders to explore current openings and identify opportunities aligned with your skills.

Search by Location and Specialty

Focus your search on major employment centers such as Boston, Cambridge, and Worcester, or look across the state for roles that fit your preferences. Refine your search by job title, industry, seniority, and other relevant criteria to find opportunities suited to your career direction.

Advance Your Career with Ladders

Ladders specializes in vetted professional jobs paying $100,000 or more. Review listings, compare role requirements, and apply to positions that align with your qualifications. Set up a complete profile and keep your resume current to make it easier to pursue your next Massachusetts opportunity.

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$74K - $91K *

Transform your career by joining a dedicated team focused on student-centered education and therapeutic support. Collaborate with professionals to implement IEPs and foster academic and social growth...

2 weeks ago

  •   Less than 5 years exp.  •   Real Estate & Construction

$74K - $91K *

Help us shape the future of students with special needs by implementing individualized education plans, tracking progress, and collaborating with a dedicated team to foster academic and emotional grow...

2 weeks ago

  •   Less than 5 years exp.  •   Real Estate & Construction

$180K - $195K *

Join a dynamic team to lead and manage clinical trials, ensuring timely execution and compliance. Collaborate with cross-functional partners and vendors to drive operational success in immunology rese...

Boston, MARemote

2 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$180K - $195K *

Lead the charge in managing complex clinical trials, ensuring timely execution, budget adherence, and compliance with regulations. Collaborate with cross-functional teams and vendors to drive operatio...

2 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$160K - $180K *

Join us to lead our accounting operations, ensuring accuracy and scalability. Drive financial reporting, audits, and team development while applying your technical expertise in a dynamic, multi-channe...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Information Technology

$75K - $175K *

Advance application security initiatives by leading manual code reviews, penetration tests, and threat modeling. Work closely with clients to strengthen their secure development processes, delivering...

United StatesRemote

Reposted 2 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$135K - $160K *

Optimize patient care through integrated, collaborative strategies as you provide tailored psychiatric support in a flexible, clinician-driven environment. Maximize your impact on treatments while enj...

4 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$112K - $225K *

Manage complex healthcare transformation projects, leading operational assessments and performance improvement initiatives. Collaborate with clinical and operational teams to deliver actionable recomm...

4 days ago

  •   5 - 7 years exp.  •   Finance & Insurance

$85K - $95K *

Design engaging multimedia content that embodies brand consistency across various formats, from print to digital. Collaborate with teams to create compelling visuals, animations, and videos that reson...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Real Estate & Construction

$130K - $150K *

Champion effective publication strategies and lead scientific communication initiatives, acting as a strategic partner to clients and teams. Navigate complex medical affairs content to drive impactful...

RemoteRemote

Reposted 1 week ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$135K - $160K *

Engage in integrated patient care as a Psychiatric Nurse Practitioner, customizing treatment plans and providing medication management and therapy. Benefit from flexible scheduling within a supportive...

4 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$110K - $130K *

Champion operational excellence by leading client delivery initiatives, enhancing relationships, and driving strategic growth. Collaborate with diverse teams to ensure successful engagements and excee...

Today

  •   Less than 5 years exp.  •   Information Technology

$112K - $125K *

Join our team to advance therapeutic discovery by designing and executing in vitro and in vivo studies, optimizing CAR constructs, and evaluating gene delivery and immune responses for next-generation...

3 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$120K *

Transform mental health care by building strategic partnerships with providers to enhance access to specialized OCD treatment. Drive growth through relationship-building, education, and effective refe...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$99K - $166K *

Elevate operational excellence by leading claims strategy, enhancing customer satisfaction, and driving revenue growth. Collaborate with cross-functional teams to implement best practices and ensure c...

1 week ago

  •   8 - 10 years exp.  •   Finance & Insurance

$120K - $165K *

Transform your career by leading revenue cycle consulting projects, managing junior staff, and driving operational improvements while building strong client relationships. Leverage your expertise in h...

United StatesRemote

4 weeks ago

  •   5 - 7 years exp.  •   Business Services

$80K - $95K *

Innovate post-acute payment integrity by developing and optimizing audit concepts for DME, home health, and infusion therapy claims. Collaborate cross-functionally to ensure compliance and enhance ope...

United StatesRemote

2 days ago

  •   5 - 7 years exp.  •   Information Technology

$150K - $180K *

Transform the clinical sales landscape by leading a regional team to drive utilization growth, enhance patient treatment metrics, and foster cross-functional collaboration for commercial success in in...

United StatesRemote

3 weeks ago

  •   8 - 10 years exp.  •   Healthcare

$136K - $156K *

Drive your career with a leadership role in nursing, overseeing patient care and staff management. Collaborate with teams to enhance service quality and ensure compliance with healthcare standards whi...

4 days ago

  •   5 - 7 years exp.  •   Healthcare

$210K - $322K *

Join a dynamic team to lead and empower Solutions Engineers, driving technical sales excellence while fostering collaborative innovation and ensuring customer success through strategic insights and re...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$252K - $283K *

Elevate clinical operations by leading the development of innovative clinical systems. Collaborate with IT and cross-functional teams to enhance trial execution, optimize processes, and leverage techn...

3 weeks ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$110K - $130K *

Innovate by developing scalable applications and data pipelines, leveraging Python and cloud platforms. Collaborate with cross-functional teams to modernize enterprise systems and enhance backend serv...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Information Technology

$68K - $113K *

Lead the charge in optimizing coding accuracy and compliance by analyzing complex patient care documentation, providing expert guidance, and enhancing coder education to ensure adherence to ethical st...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Business Services

$80K - $95K *

Drive excellence in MRI imaging by leading a skilled team, ensuring high-quality patient care, and maintaining operational standards. Collaborate with radiologists and support staff to enhance diagnos...

1 week ago

  •   5 - 7 years exp.  •   Hospitals & Medical Centers

$81K - $116K *

Champion patient care by performing C.A.T. scans, ensuring comfort and safety. Collaborate with radiologists to deliver high-quality imaging while adhering to safety protocols and maintaining a clean...

1 week ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

Frequently Asked Questions (FAQ)

  • What types of $100,000+ jobs can I find in Massachusetts?question toggle

    Listings may include professional and leadership roles across fields such as technology, healthcare, finance, biotechnology, education, manufacturing, and business services. Available positions change, so browse current listings for the latest opportunities.

  • Where can I find professional jobs in Massachusetts?question toggle

    Search across the state, including major employment centers such as Boston, Cambridge, and Worcester. You can also use location filters to explore roles in other Massachusetts communities.

  • Are the Massachusetts jobs on Ladders vetted?question toggle

    Ladders features vetted professional job listings paying $100,000 or more. Review each listing for details about the employer, responsibilities, qualifications, and compensation.

  • How can I find a Massachusetts job that matches my experience?question toggle

    Use filters such as location, job title, industry, and seniority to narrow your search. Keep your resume current and compare each listing’s requirements with your skills and career goals.