Find $100K+ Jobs in Massachusetts

Explore professional opportunities across Massachusetts with Ladders. Browse vetted jobs paying $100,000 or more, from roles in Boston and Cambridge to opportunities in Worcester, Springfield, and other communities throughout the state. Whether you’re pursuing your next leadership position or advancing your career in a specialized field, discover openings that match your experience and goals.

Explore Massachusetts Career Opportunities

Massachusetts is home to a diverse economy with employers in technology, healthcare, financial services, education, biotechnology, manufacturing, and professional services. Job availability and compensation vary by employer, role, and experience. Use Ladders to explore current openings and identify opportunities aligned with your skills.

Search by Location and Specialty

Focus your search on major employment centers such as Boston, Cambridge, and Worcester, or look across the state for roles that fit your preferences. Refine your search by job title, industry, seniority, and other relevant criteria to find opportunities suited to your career direction.

Advance Your Career with Ladders

Ladders specializes in vetted professional jobs paying $100,000 or more. Review listings, compare role requirements, and apply to positions that align with your qualifications. Set up a complete profile and keep your resume current to make it easier to pursue your next Massachusetts opportunity.

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$120K - $150K *

Elevate pediatric dental care by joining our collaborative team, where you'll provide exceptional treatment to children in a supportive, high-volume practice. Enjoy a fulfilling role that fosters last...

United StatesRemote

Today

  •   Less than 5 years exp.  •   Healthcare

$120K - $144K *

Join a team that's dedicated to providing exceptional dental care to children. This role offers the chance to build lasting relationships in a supportive, multi-doctor environment while utilizing mode...

United StatesRemote

Today

  •   Less than 5 years exp.  •   Healthcare

$150K - $180K *

Shape the future of healthcare policy by executing legal strategies that enhance access to products. Collaborate cross-functionally to influence federal and state initiatives while providing expert le...

1 week ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$172K - $223K *

Champion operational excellence as a strategic leader, driving performance and financial results across the PacWest Region while ensuring safety, quality, and compliance in a mission-driven environmen...

United StatesRemote

5 days ago

  •   11 - 15 years exp.  •   Healthcare

$270K - $291K *

Advance patient care by delivering anesthesia expertise in a collaborative environment. Join a dedicated team managing diverse surgical cases, while engaging in patient assessments, airway management...

4 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$129K - $177K *

Join a team that's shaping the future of healthcare technology by providing strategic architectural leadership and driving the design of scalable, cloud-native solutions that enhance experiences for m...

United StatesRemote

2 days ago

  •   8 - 10 years exp.  •   Healthcare

$80K - $100K *

Drive operational excellence as you enhance IT processes, ensuring compliance and efficiency across systems. Collaborate with cross-functional teams to automate workflows and manage user lifecycle act...

Reposted 4 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$232K - $331K *

Deliver impactful leadership in clinical operations, overseeing 24/7 command centers and driving strategic initiatives to enhance patient care and operational efficiency in a high-stakes environment...

2 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$125K - $235K *

Drive operational excellence in healthcare by leading transformative initiatives, optimizing workflows, and enhancing provider productivity. Collaborate with teams to deliver data-driven solutions tha...

United StatesRemote

Today

  •   Less than 5 years exp.  •   Healthcare

$233K - $316K *

Lead the charge in HCP marketing strategy and execution, driving growth across multiple products while developing a high-performing team and collaborating with cross-functional partners to enhance cus...

2 weeks ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$225K - $281K *

Join a team that's pushing the boundaries of oncology research! This key role involves designing and leading clinical trials, ensuring data integrity, and collaborating with global experts to advance...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$225K - $281K *

Explore your career in clinical development as you design and lead innovative oncology studies, ensuring data integrity and compliance while collaborating with cross-functional teams and cultivating r...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$200K - $215K *

Advance the cloud platform capabilities, ensuring secure, reliable, and scalable product delivery while enhancing developer experience and shaping reliability practices in a mission-driven healthcare...

United StatesRemote

3 weeks ago

  •   8 - 10 years exp.  •   Healthcare

$110K - $130K *

Support clients in maximizing their Workday investment by implementing and enhancing Adaptive Planning solutions. Drive project success through relationship building, best practices, and exceptional s...

RemoteRemote

3 weeks ago

  •   Less than 5 years exp.  •   Business Services

$95K - $100K *

Elevate clinical services by managing Positive Behavior Support for individuals with developmental disabilities, ensuring effective collaboration across divisions and enhancing community resources for...

Today

  •   Less than 5 years exp.  •   Healthcare

$122K - $212K *

Drive strategic capacity management and operational excellence in external manufacturing. Collaborate with cross-functional teams to enhance supply chain efficiency, ensuring compliance and cost-effec...

Yesterday

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$184K - $396K *

Lead our clinical strategy in the West Region, driving performance in cost, quality, and member experience through partnerships with healthcare providers. Collaborate with teams to enhance value-based...

RemoteRemote

Reposted 5 days ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$250K - $285K *

Accelerate progress at the helm of accounting operations, ensuring compliance with GAAP and SEC standards. Lead a high-performing team while optimizing financial systems and enhancing reporting accura...

3 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$167K - $207K *

Lead the charge in shaping regulatory operations by enhancing submission processes, governance, and systems. Drive high-quality global submissions while fostering collaboration and visibility across t...

2 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$219K - $235K *

Champion strategic clinical program leadership, ensuring high-quality execution and collaboration across teams to advance R&D initiatives and lifecycle management in a flexible hybrid work environment...

2 days ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$157K - $256K *

Champion strategic engagements with oncology thought leaders to enhance insights and drive initiatives for our Solid Tumor portfolio, focusing on collaboration across teams and executing regional stra...

United StatesRemote

3 days ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$110K - $130K *

Provide exceptional patient care as an Advanced Practice Nurse in a dynamic Float Pool environment, collaborating with healthcare teams to ensure optimal outcomes through assessment, treatment plannin...

3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$123K - $168K *

Explore the potential of Neurocrine products by managing key accounts, driving sales growth, and fostering relationships with healthcare professionals. Collaborate cross-functionally to enhance produc...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$110K - $140K *

Join a team that's dedicated to delivering exceptional patient care while collaborating in a supportive environment. Utilize your skills in diagnosing and treating complex illnesses, ensuring holistic...

2 weeks ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$75K - $100K *

Join a team that's dedicated to providing integrated behavioral health care in a fast-paced environment. Collaborate with primary care teams to support pediatric and adolescent patients using evidence...

Today

  •   Less than 5 years exp.  •   Healthcare

Frequently Asked Questions (FAQ)

  • What types of $100,000+ jobs can I find in Massachusetts?question toggle

    Listings may include professional and leadership roles across fields such as technology, healthcare, finance, biotechnology, education, manufacturing, and business services. Available positions change, so browse current listings for the latest opportunities.

  • Where can I find professional jobs in Massachusetts?question toggle

    Search across the state, including major employment centers such as Boston, Cambridge, and Worcester. You can also use location filters to explore roles in other Massachusetts communities.

  • Are the Massachusetts jobs on Ladders vetted?question toggle

    Ladders features vetted professional job listings paying $100,000 or more. Review each listing for details about the employer, responsibilities, qualifications, and compensation.

  • How can I find a Massachusetts job that matches my experience?question toggle

    Use filters such as location, job title, industry, and seniority to narrow your search. Keep your resume current and compare each listing’s requirements with your skills and career goals.