Find $100K+ Jobs in Massachusetts

Explore professional opportunities across Massachusetts with Ladders. Browse vetted jobs paying $100,000 or more, from roles in Boston and Cambridge to opportunities in Worcester, Springfield, and other communities throughout the state. Whether you’re pursuing your next leadership position or advancing your career in a specialized field, discover openings that match your experience and goals.

Explore Massachusetts Career Opportunities

Massachusetts is home to a diverse economy with employers in technology, healthcare, financial services, education, biotechnology, manufacturing, and professional services. Job availability and compensation vary by employer, role, and experience. Use Ladders to explore current openings and identify opportunities aligned with your skills.

Search by Location and Specialty

Focus your search on major employment centers such as Boston, Cambridge, and Worcester, or look across the state for roles that fit your preferences. Refine your search by job title, industry, seniority, and other relevant criteria to find opportunities suited to your career direction.

Advance Your Career with Ladders

Ladders specializes in vetted professional jobs paying $100,000 or more. Review listings, compare role requirements, and apply to positions that align with your qualifications. Set up a complete profile and keep your resume current to make it easier to pursue your next Massachusetts opportunity.

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$85K - $105K *

Join a team that's dedicated to enhancing the quality of care in our Home Health and Private Duty department. Oversee operations, support caregivers, and ensure compliance while fostering teamwork and...

Yesterday

  •   Less than 5 years exp.  •   Healthcare

$385K - $405K *

Transform drug safety and pharmacovigilance by leading global strategies, ensuring compliance, and providing expert medical oversight. Collaborate with cross-functional teams to enhance patient safety...

1 week ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$231K - $363K *

Grow your career with a dynamic sales role focused on building enterprise partnerships. Drive impactful healthcare solutions by engaging with HR leaders and managing the full sales cycle across the No...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$225K - $250K *

Transform operations by leading a diverse team to enhance profitability and efficiency across multiple sites, while building strategic relationships with clients and driving growth initiatives in the...

RemoteRemote

Today

  •   8 - 10 years exp.  •   Healthcare

$115K - $198K *

Join a dynamic team as you lead innovative clinical programs, enhancing care solutions across oncology and cardiovascular disease. Collaborate with stakeholders to improve member experiences and clini...

2 days ago

  •   5 - 7 years exp.  •   Hospitals & Medical Centers

$165K - $200K *

Innovate and drive operational excellence by delivering High Reliability and Human Performance transformations that boost organizational effectiveness and resilience across various complex environment...

RemoteRemote

Reposted 2 weeks ago

  •   5 - 7 years exp.  •   Business Services

$100K - $120K *

Unlock potential by mentoring new providers through virtual education, ensuring a seamless onboarding experience. Leverage your clinical expertise to foster growth in both primary care and behavioral...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$141K - $239K *

Drive impactful clinical experiences by leading product strategy and discovery. Collaborate with cross-functional teams to enhance workflows using AI, ensuring measurable outcomes and improved clinici...

2 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$136K - $187K *

Unlock potential by serving as a vital resource for patients and caregivers, providing education and support for managing generalized Myasthenia Gravis while coordinating treatment and navigating insu...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$80K - $95K *

Transform patient care by providing coordinated, family-centered nursing in an outpatient setting. Collaborate with a multidisciplinary team to manage complex pain and headache concerns for children a...

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$87K - $117K *

Unlock potential by leading the design, deployment, and support of Unified Communications platforms, ensuring optimal performance and compliance while collaborating with vendors and teams to manage la...

United StatesRemote

4 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$80K - $95K *

Join a team that's dedicated to enhancing patient safety through data analysis, audits, and collaboration across departments. Drive improvements in EHR software and support quality initiatives to ensu...

United StatesRemote

2 days ago

  •   5 - 7 years exp.  •   Healthcare

$150K - $200K *

Transform lives by providing virtual therapy and developing personalized treatment plans. Collaborate with a dedicated team to deliver compassionate, evidence-based care while enjoying the flexibility...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$180K - $220K *

Transform the future of care navigation by leading clinical evaluations and developing protocols in a telehealth setting, guiding team efforts to ensure high-quality, patient-centered care for complex...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$210K - $250K *

Join a dynamic mental health team as a Collaborating Psychiatrist, providing clinical oversight and direct patient care. Engage in meaningful collaboration with PMHNPs while ensuring compliance and de...

RemoteRemote

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$150K - $200K *

Transform medical education design by leading strategy and growth initiatives globally. Collaborate with diverse teams to enhance learning environments and expand institutional partnerships, driving i...

1 week ago

  •   11 - 15 years exp.  •   Real Estate & Construction

$210K - $250K *

Join a team that's dedicated to providing high-quality rehabilitative care. As an Internal Medicine Physician, you'll manage complex inpatient cases, collaborate with a multidisciplinary team, and enh...

1 week ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$580K+ *

Lead the charge in providing exemplary anesthesia care across multiple facilities while collaborating with a skilled team of professionals, ensuring optimal patient outcomes and a balanced work-life e...

Reposted 3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$295K - $380K *

Join a dynamic team as a strategic leader in global medical affairs, driving innovative strategies and evidence generation for neurometabolic diseases. Collaborate cross-functionally to enhance patien...

1 week ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$180K - $195K *

Tackle complex science in the healthcare space! Lead medical strategy, shape impactful narratives, and foster collaboration across teams to drive behavior change and enhance patient outcomes. Inspire...

Reposted 1 week ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$180K - $195K *

Elevate healthcare marketing by transforming complex science into impactful strategies. Lead multidisciplinary teams to inspire creativity, drive behavior change, and build trusted client relationship...

RemoteRemote

Reposted 1 week ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$88K - $105K *

Join a team that's dedicated to advancing Alzheimer's research through innovative study design and execution, utilizing cutting-edge techniques and large data analysis to explore disease mechanisms an...

2 weeks ago

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$173K - $320K *

Shape the future of rheumatology by providing strategic medical oversight across clinical trials. Lead the innovation and development of groundbreaking therapies while collaborating with multidiscipli...

RemoteRemote

Reposted 1 week ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$163K - $218K *

Lead the strategy and delivery of enterprise applications, optimizing technology platforms to enhance clinical care and business operations. Collaborate with cross-functional teams to drive improvemen...

United StatesRemote

6 days ago

  •   11 - 15 years exp.  •   Healthcare

$112K - $125K *

Transform the nursing department's quality standards while collaborating with staff at all levels to ensure excellent patient care and employee development. Promote a culture of continuous improvement...

Reposted 3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

Frequently Asked Questions (FAQ)

  • What types of $100,000+ jobs can I find in Massachusetts?question toggle

    Listings may include professional and leadership roles across fields such as technology, healthcare, finance, biotechnology, education, manufacturing, and business services. Available positions change, so browse current listings for the latest opportunities.

  • Where can I find professional jobs in Massachusetts?question toggle

    Search across the state, including major employment centers such as Boston, Cambridge, and Worcester. You can also use location filters to explore roles in other Massachusetts communities.

  • Are the Massachusetts jobs on Ladders vetted?question toggle

    Ladders features vetted professional job listings paying $100,000 or more. Review each listing for details about the employer, responsibilities, qualifications, and compensation.

  • How can I find a Massachusetts job that matches my experience?question toggle

    Use filters such as location, job title, industry, and seniority to narrow your search. Keep your resume current and compare each listing’s requirements with your skills and career goals.