Explore $100K+ Jobs in Pennsylvania

Discover vetted professional opportunities across Pennsylvania with Ladders. Browse jobs with salaries of $100,000 or more, from senior leadership and management roles to specialized positions in technology, healthcare, finance, engineering, and other fields. Whether you’re looking in Philadelphia, Pittsburgh, Harrisburg, or elsewhere in the state, explore openings that match your experience and career goals.

Find opportunities across Pennsylvania

Pennsylvania’s major cities and regional business centers offer a wide range of professional career paths. Search for opportunities in metropolitan areas such as Philadelphia and Pittsburgh, as well as roles in Harrisburg, Allentown, Lancaster, and other communities. Availability varies by employer and location, so review each listing for work location and remote or hybrid details.

Browse senior and specialized roles

Explore positions for experienced professionals, including director, vice president, executive, and other senior-level roles. You can also find specialized opportunities in areas such as technology, healthcare, finance, sales, operations, and engineering. Review job requirements, responsibilities, and compensation information to identify roles suited to your expertise.

Make your next career move

Use Ladders to explore vetted jobs paying $100,000 or more in Pennsylvania. Compare opportunities, focus your search by location and profession, and apply to positions aligned with your qualifications. New listings may be added as employers seek experienced talent across the state.

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$150K - $180K *

Lead the charge in designing a cutting-edge platform for modern data centers, integrating AI and cloud technologies. Collaborate with cross-functional teams to build a robust, scalable architecture th...

United StatesRemote

Yesterday

  •   8 - 10 years exp.  •   Information Technology

$124K - $280K *

Champion innovative AI-driven product development in the pharmaceutical sector. Lead a diverse team, driving an AI-first mindset while ensuring quality and performance across complex data and analytic...

Today

  •   5 - 7 years exp.  •   Legal & Accounting

$130K - $155K *

Join a dynamic team to define and implement enterprise architecture frameworks that align technology solutions with strategic IT objectives, ensuring security, scalability, and operational efficiency...

United StatesRemote

6 days ago

  •   5 - 7 years exp.  •   Enterprise Technology

$120K - $202K *

Redefine enterprise integration security by designing robust architectures and ensuring compliance across diverse applications and cloud environments. Collaborate with cross-functional teams to enhanc...

Reposted 3 days ago

  •   11 - 15 years exp.  •   Finance & Insurance

$150K - $160K *

Partner with us to shape the quality strategy for a leading exam development platform. Leverage your expertise to guide multiple Agile teams, enhance automation practices, and ensure high standards ac...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Education, Government & Non-Profit

$90K - $189K *

Shape the future of network infrastructure by leading modernization efforts across classified and unclassified systems. Collaborate with teams to design secure, high-performance networks while ensurin...

RemoteRemote

Today

  •   5 - 7 years exp.  •   Information Technology

$150K - $180K *

Elevate enterprise AI strategy by architecting scalable solutions, ensuring responsible governance, and mentoring teams. Collaborate with cross-functional leaders to drive AI adoption and deliver high...

2 weeks ago

  •   8 - 10 years exp.  •   Information Technology

$95K - $115K *

Empower your career by designing and maintaining robust network infrastructures. Collaborate with a dynamic team to optimize performance, security, and reliability across LAN/WAN, Windows Server, and...

Yesterday

  •   8 - 10 years exp.  •   Manufacturing & Automotive

$160K - $185K *

Join a team that's transforming customer experiences through innovative technical solutions. As a Solutions Architect, you'll bridge business needs with technology, guiding clients from discovery to d...

United StatesRemote

Today

  •   Less than 5 years exp.  •   Information Technology

$110K - $130K *

Drive operational excellence by enhancing reliability and performance of a SaaS platform. Collaborate with development teams to implement automation, incident management, and observability practices...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Enterprise Technology

$160K - $170K *

Join a team that designs scalable and secure technology solutions by collaborating with various stakeholders. You'll lead architecture efforts for enterprise-level projects and shape our Enterprise Ar...

United StatesRemote

Reposted 3 weeks ago

  •   5 - 7 years exp.  •   Transportation

$172K - $240K *

Join a team that's redefining AI security! As a Principal AI Security Engineer, you'll lead assessments, design controls, and partner with teams to ensure safe AI adoption across the enterprise, drivi...

United StatesRemote

3 weeks ago

  •   8 - 10 years exp.  •   Information Technology

$152K - $269K *

Explore the forefront of enterprise AI solutions by pioneering innovative architectures and prototypes that solve complex business problems. You will cultivate relationships, drive technical wins, and...

United StatesRemote

Reposted 3 weeks ago

  •   8 - 10 years exp.  •   Information Technology

$190K - $200K *

Lead the charge in electrical engineering excellence across multiple campuses, ensuring robust design, validation, and energization of critical infrastructure while integrating onsite generation solut...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Information Technology

$145K - $175K *

Join a team that's redefining cloud solutions by architecting innovative CaaS and cloud-native technologies. Collaborate with customers to tackle complex challenges and drive successful cloud transfor...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Manufacturing & Automotive

$150K - $180K *

Contribute to the secure integration and deployment of AI/ML systems by providing specialized security architecture guidance, ensuring protection of mission data and compliance with cybersecurity fram...

Yesterday

  •   8 - 10 years exp.  •   Enterprise Technology

$160K - $297K *

Redefine the digital workplace by leading the design and governance of Microsoft 365 solutions, ensuring strategic alignment, security, and innovation across the enterprise. Collaborate with cross-fun...

United StatesRemote

4 weeks ago

  •   8 - 10 years exp.  •   Manufacturing & Automotive

$320K - $488K *

Join a team that's pushing the boundaries of innovation in rack-scale system software. Lead technical design efforts, collaborate with top industry players, and drive quality across a rapidly evolving...

United StatesRemote

Reposted 2 days ago

  •   11 - 15 years exp.  •   Manufacturing & Automotive

$100K - $120K *

Drive security excellence by managing identity access, external testing, and compliance processes. Collaborate with teams to enhance AWS security and develop scalable policies, ensuring robust protect...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$75K - $85K *

Engage in collaborative architectural design and strategic planning, leading projects of varying complexity while fostering client relationships and supporting business development efforts across regi...

Reposted yesterday

  •   5 - 7 years exp.  •   Real Estate & Construction

$145K - $175K *

Transform the future of mobile technology by leading technical solutions across multi-MNO systems. Collaborate with cross-functional teams to ensure seamless integration and service assurance for inte...

1 week ago

  •   8 - 10 years exp.  •   Hospitality & Recreation

$108K - $130K *

Advance system design excellence by collaborating with cross-functional teams, ensuring quality and timely delivery of specifications, and managing technical risks while driving continuous improvement...

2 weeks ago

  •   Less than 5 years exp.  •   Energy & Utilities

$105K - $115K *

Optimize security measures by leading technical solutions to mitigate information risks. Ensure compliance with corporate policies and oversee incident response, safeguarding all computing platforms a...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Retail & Consumer Goods

$135K - $160K *

Lead enterprise architecture strategy across Oracle CX, ERP, HCM, and SCM Cloud. Collaborate with stakeholders to develop scalable solutions, ensuring alignment with business capabilities and technolo...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Staffing

$130K - $160K *

Shape the future of retail by architecting innovative AI solutions that drive business success. Collaborate with cross-functional teams to integrate open-source technologies and enhance operational ef...

Philadelphia, PARemote

Reposted 3 weeks ago

  •   8 - 10 years exp.  •   Retail & Consumer Goods

Frequently Asked Questions (FAQ)

  • What types of $100K+ jobs can I find in Pennsylvania?question toggle

    Pennsylvania listings may include senior management, executive, and specialized professional roles in fields such as technology, healthcare, finance, sales, operations, and engineering. Roles and availability vary by employer.

  • Which Pennsylvania cities have professional job opportunities?question toggle

    Opportunities may be available in Philadelphia, Pittsburgh, Harrisburg, Allentown, Lancaster, and other areas across the state. Check each listing for its specific location and work arrangement.

  • Are these Pennsylvania jobs vetted?question toggle

    Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review individual listings for details about the employer, qualifications, responsibilities, and compensation.

  • Can I find remote or hybrid jobs in Pennsylvania?question toggle

    Some employers may offer remote or hybrid arrangements, but availability varies. Check the work-location details in each job listing.