Explore $100K+ Jobs in Pennsylvania

Discover vetted professional opportunities across Pennsylvania with Ladders. Browse jobs with salaries of $100,000 or more, from senior leadership and management roles to specialized positions in technology, healthcare, finance, engineering, and other fields. Whether you’re looking in Philadelphia, Pittsburgh, Harrisburg, or elsewhere in the state, explore openings that match your experience and career goals.

Find opportunities across Pennsylvania

Pennsylvania’s major cities and regional business centers offer a wide range of professional career paths. Search for opportunities in metropolitan areas such as Philadelphia and Pittsburgh, as well as roles in Harrisburg, Allentown, Lancaster, and other communities. Availability varies by employer and location, so review each listing for work location and remote or hybrid details.

Browse senior and specialized roles

Explore positions for experienced professionals, including director, vice president, executive, and other senior-level roles. You can also find specialized opportunities in areas such as technology, healthcare, finance, sales, operations, and engineering. Review job requirements, responsibilities, and compensation information to identify roles suited to your expertise.

Make your next career move

Use Ladders to explore vetted jobs paying $100,000 or more in Pennsylvania. Compare opportunities, focus your search by location and profession, and apply to positions aligned with your qualifications. New listings may be added as employers seek experienced talent across the state.

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$95K - $178K *

Join the mission to enhance inventory management of classified Nuclear Weapons Related Materiel for the US Navy's Fleet Ballistic Missile Program, ensuring compliance and accuracy while collaborating...

1 week ago

  •   Less than 5 years exp.  •   Aerospace & Defense

$125K - $150K *

Join a team that's redefining cloud solutions by architecting and delivering complex Azure engagements. Lead migrations, mentor engineers, and drive innovation while ensuring robust security and gover...

United StatesRemote

3 days ago

  •   8 - 10 years exp.  •   Enterprise Technology

$120K - $175K *

Shape the future of defense solutions by leveraging C5ISR expertise to develop mission-focused strategies for the U.S. Army and Department of War, ensuring alignment with customer priorities and acqui...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Technical Services

$88K - $105K *

Optimize verification strategies and lead hands-on testing to enhance product reliability. Collaborate across engineering disciplines to translate requirements into effective test methods, driving imp...

1 week ago

  •   Less than 5 years exp.  •   Technical Services

$55K - $151K *

Empower teams to enhance productivity through automated workflows, bridging development, operations, and security. Cultivate client relationships while navigating complex challenges and delivering hig...

2 weeks ago

  •   Less than 5 years exp.  •   Legal & Accounting

$96K - $148K *

Lead the charge in designing and building secure integrations for enterprise ITSM platforms. Analyze data flows, enhance system connections, and ensure compliance while delivering resilient solutions...

United StatesRemote

1 month ago

  •   8 - 10 years exp.  •   Enterprise Technology

$120K - $145K *

Drive impactful software solutions by embedding with clients, transforming ambiguous needs into deployable features across secure environments. Collaborate closely with users and stakeholders to deliv...

United StatesRemote

6 days ago

  •   5 - 7 years exp.  •   Enterprise Technology

$110K - $149K *

Elevate your career by collaborating with top partners to drive technical sales, deliver impactful training, and enhance product adoption. Join a dynamic team focused on fostering creativity and accou...

United StatesRemote

Yesterday

  •   Less than 5 years exp.  •   Enterprise Technology

$90K - $110K *

Drive the advancement of our Governance, Risk, and Compliance program by monitoring compliance, managing vendor risks, and leading audits. Collaborate across teams to ensure effective policy implement...

United StatesRemote

1 month ago

  •   Less than 5 years exp.  •   Information Technology

$80K - $95K *

Lead the charge in managing mechanical and electrical systems for aviation projects, ensuring timely, safe, and budget-compliant construction while fostering collaboration among project teams and stak...

1 week ago

  •   Less than 5 years exp.  •   Real Estate & Construction

$169K - $253K *

Transform operational technology by leading the design and implementation of scalable SCADA and telemetry solutions, ensuring secure data delivery and operational visibility across multi-site environm...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Enterprise Technology

$100K - $120K *

Lead the charge in managing workplace design and construction projects, ensuring operational readiness and accountability across multiple sites while optimizing budgets and vendor performance for succ...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$120K - $145K *

Transform client experiences by leading the design and implementation of Oracle HCM Cloud solutions. Collaborate with teams to ensure scalable, reliable, and high-performance technical architectures t...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Staffing

$150K - $180K *

Lead the charge in designing and implementing innovative software systems for cutting-edge healthcare SaaS platforms, driving technical excellence and strategic collaboration across teams to achieve i...

United StatesRemote

Reposted 1 week ago

  •   8 - 10 years exp.  •   Business Services

$230K - $275K *

Lead the charge in vulnerability research and exploitation techniques, transforming real-world threats into automated solutions. Collaborate with teams to enhance security measures and validate defens...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Information Technology

$181K - $301K *

Transform your career by leading a global cyber defense team, driving proactive strategies to mitigate risks and enhance security across diverse environments. Collaborate with cross-functional teams t...

RemoteRemote

Reposted 2 weeks ago

  •   8 - 10 years exp.  •   Healthcare

$80K - $95K *

Seeking a proactive Test Engineer to lead integration and verification of software products, ensuring compliance with specifications through automated and manual testing. Collaborate within R&D to enh...

4 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$80K - $155K *

Join a team that's redefining energy solutions by designing innovative fluid and power systems. As a Process Engineer, you'll drive the development and optimization of cutting-edge technologies in a f...

RemoteRemote

1 week ago

  •   Less than 5 years exp.  •   Energy & Utilities

$80K - $95K *

Optimize your career by providing critical analytical support for hardware and software installations across various platforms, ensuring compliance with regulations and enhancing operational efficienc...

United StatesRemote

6 days ago

  •   Less than 5 years exp.  •   Information Technology

$114K - $200K *

Champion growth by leading the Enterprise Sales team, driving member acquisition, and executing strategic sales initiatives in the cybersecurity sector. Collaborate with stakeholders to enhance sales...

United StatesRemote

Yesterday

  •   5 - 7 years exp.  •   Information Technology

$91K - $179K *

Design and implement innovative analytics solutions that enhance Human Capital services, leveraging AI and data engineering to deliver actionable insights and scalable data pipelines for diverse clien...

1 week ago

  •   Less than 5 years exp.  •   Business Services

$91K - $179K *

Transform data into actionable insights by designing and implementing analytics solutions that enhance workforce strategies. Collaborate with cross-functional teams to deliver innovative AI-driven pro...

1 week ago

  •   Less than 5 years exp.  •   Business Services

$110K - $130K *

Lead the charge in transforming client operations by identifying and accelerating AI-driven opportunities. Collaborate with stakeholders to frame business challenges, prototype solutions, and drive me...

United StatesRemote

Reposted 1 week ago

  •   5 - 7 years exp.  •   Information Technology

$80K - $95K *

Engage in strategic proposal management, leading RFQ/RFP responses across divisions. Collaborate with teams to ensure timely, compliant submissions while maintaining high-quality standards and support...

RemoteRemote

2 weeks ago

  •   5 - 7 years exp.  •   Real Estate & Construction

$80K - $95K *

Champion healthcare innovation by optimizing EHR workflows and systems. Collaborate with clinical staff to address complex information system issues, enhance user training, and ensure data integrity...

Reposted 1 week ago

  •   5 - 7 years exp.  •   Hospitals & Medical Centers

Frequently Asked Questions (FAQ)

  • What types of $100K+ jobs can I find in Pennsylvania?question toggle

    Pennsylvania listings may include senior management, executive, and specialized professional roles in fields such as technology, healthcare, finance, sales, operations, and engineering. Roles and availability vary by employer.

  • Which Pennsylvania cities have professional job opportunities?question toggle

    Opportunities may be available in Philadelphia, Pittsburgh, Harrisburg, Allentown, Lancaster, and other areas across the state. Check each listing for its specific location and work arrangement.

  • Are these Pennsylvania jobs vetted?question toggle

    Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review individual listings for details about the employer, qualifications, responsibilities, and compensation.

  • Can I find remote or hybrid jobs in Pennsylvania?question toggle

    Some employers may offer remote or hybrid arrangements, but availability varies. Check the work-location details in each job listing.