Explore $100K+ Jobs in Pennsylvania

Discover vetted professional opportunities across Pennsylvania with Ladders. Browse jobs with salaries of $100,000 or more, from senior leadership and management roles to specialized positions in technology, healthcare, finance, engineering, and other fields. Whether you’re looking in Philadelphia, Pittsburgh, Harrisburg, or elsewhere in the state, explore openings that match your experience and career goals.

Find opportunities across Pennsylvania

Pennsylvania’s major cities and regional business centers offer a wide range of professional career paths. Search for opportunities in metropolitan areas such as Philadelphia and Pittsburgh, as well as roles in Harrisburg, Allentown, Lancaster, and other communities. Availability varies by employer and location, so review each listing for work location and remote or hybrid details.

Browse senior and specialized roles

Explore positions for experienced professionals, including director, vice president, executive, and other senior-level roles. You can also find specialized opportunities in areas such as technology, healthcare, finance, sales, operations, and engineering. Review job requirements, responsibilities, and compensation information to identify roles suited to your expertise.

Make your next career move

Use Ladders to explore vetted jobs paying $100,000 or more in Pennsylvania. Compare opportunities, focus your search by location and profession, and apply to positions aligned with your qualifications. New listings may be added as employers seek experienced talent across the state.

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$120K - $145K *

Take ownership of automating workflows across teams by building AI agents using Claude and Microsoft Copilot. Collaborate with various departments to identify automation opportunities, ensuring securi...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Information Technology

$74K - $130K *

Elevate your career by leading design efforts in transportation projects, utilizing OpenRoads Designer. Collaborate with engineers to deliver high-quality solutions while ensuring compliance with stan...

United StatesRemote

3 weeks ago

  •   8 - 10 years exp.  •   Real Estate & Construction

$110K - $130K *

Unlock your potential by driving sales of innovative Employee Comms solutions. Collaborate with partners and peers to enhance customer engagement and revenue growth while showcasing your expertise in...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Enterprise Technology

$115K - $172K *

Join a team that's driving strategic sales in cyber security and networking. Leverage your expertise to manage key accounts, develop relationships, and achieve revenue goals while navigating complex b...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Information Technology

$110K - $130K *

Champion the administration of Google Cloud and Gemini Enterprise environments, ensuring secure, scalable configurations. Collaborate with IT and business teams to optimize cloud services and support...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$180K - $240K *

Drive cross-domain visibility and coordination in a dynamic engineering environment. As the sole TPM, you'll ensure programs are on track, dependencies are mapped, and automation enhances efficiency a...

United StatesRemote

Yesterday

  •   8 - 10 years exp.  •   Information Technology

$180K - $240K *

Transform the future of distributed systems by designing and building robust platform components. Collaborate with teams to ensure reliability and scalability in mission-critical environments, driving...

United StatesRemote

3 weeks ago

  •   8 - 10 years exp.  •   Healthcare

$120K - $170K *

Transform enterprise software systems by leading design and development efforts, ensuring scalable, secure applications that meet federal mission needs while mentoring engineers and driving best pract...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Information Technology

$80K - $95K *

Partner with us to develop innovative, luxury card designs that elevate brand identity. You'll collaborate with cross-functional teams to ensure visual excellence and compliance while creating stunnin...

Reposted 3 days ago

  •   5 - 7 years exp.  •   Business Services

$76K - $118K *

Explore a pivotal role in enhancing operational technology solutions for Army facilities. Collaborate with diverse teams to ensure system security, reliability, and compliance while supporting moderni...

United StatesRemote

2 weeks ago

  •   11 - 15 years exp.  •   Enterprise Technology

$100K - $120K *

Drive the development and integration of advanced nuclear energy systems by applying systems engineering methods to translate objectives into clear, verifiable requirements and solutions, while collab...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Energy & Utilities

$100K - $120K *

Analyze customer needs and advance technical solutions in cybersecurity, collaborating with sales and product teams to deliver impactful presentations and proposals while ensuring seamless product int...

United StatesRemote

Reposted 3 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$116K - $215K *

Champion the development of advanced avionics systems, leading cross-functional teams to ensure compliance and performance. Drive technical presentations and analyses, validating design margins and en...

2 weeks ago

  •   8 - 10 years exp.  •   Aerospace & Defense

$116K - $215K *

Lead the charge in developing cutting-edge avionics systems, ensuring compliance and performance from concept to qualification. Collaborate with cross-functional teams to deliver innovative aerospace...

2 weeks ago

  •   8 - 10 years exp.  •   Aerospace & Defense

$145K - $150K *

Grow your career with a collaborative team focused on public health solutions. As a Senior Salesforce Developer, you'll leverage your expertise to enhance health department systems nationwide within a...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Enterprise Technology

$120K - $140K *

Drive the development and optimization of GTM strategies, leveraging automation and campaign execution across multiple platforms to enhance pipeline generation and account prioritization in a dynamic...

United StatesRemote

Reposted 1 week ago

  •   Less than 5 years exp.  •   Information Technology

$120K - $145K *

Join a team that's driving financial excellence in manufacturing operations. As a strategic partner, you'll enhance profitability through insightful analysis, budgeting, and capital management while f...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Transportation

$145K - $225K *

Lead the charge in software development, driving innovation and collaboration across teams. Oversee strategic planning and team development to enhance product quality and efficiency, while fostering a...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Information Technology

$120K - $145K *

Unlock potential by driving technology initiatives that enhance operations, streamline processes, and improve data utilization across the organization, while leading tuck-in integrations and maximizin...

1 month ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$137K - $235K *

Join us in shaping the future of safety analytics by leading architecture and data solutions on Google Cloud Platform. Collaborate with cross-functional teams to deliver compliant, scalable data produ...

3 days ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$150K - $180K *

Lead the development and operation of a cutting-edge Security Observability & Data Platform, enhancing endpoint security, threat detection, and incident response while driving innovation in security s...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Information Technology

$95K - $115K *

Transform enterprise analytics by developing and optimizing Power BI solutions. Collaborate with users to enhance data literacy and performance while ensuring adherence to governance standards and tro...

3 days ago

  •   Less than 5 years exp.  •   Food & Beverages

$275K - $300K *

Join a dynamic team as you lead quality and technical governance for mission-critical facilities, ensuring operational readiness and continuous improvement across the facility lifecycle from design to...

United StatesRemote

3 weeks ago

  •   8 - 10 years exp.  •   Information Technology

$100K - $120K *

Elevate traffic management solutions by driving revenue through strategic partnerships with government agencies. Cultivate relationships, identify opportunities, and execute sales strategies to achiev...

United StatesRemote

2 days ago

  •   5 - 7 years exp.  •   Transportation

$70K - $104K *

Join a dynamic HR team to drive full-cycle recruitment, engage top talent, and optimize hiring strategies. Collaborate with hiring managers to build strong candidate pipelines and enhance the recruitm...

Reposted 2 days ago

  •   Less than 5 years exp.  •   Transportation

Frequently Asked Questions (FAQ)

  • What types of $100K+ jobs can I find in Pennsylvania?question toggle

    Pennsylvania listings may include senior management, executive, and specialized professional roles in fields such as technology, healthcare, finance, sales, operations, and engineering. Roles and availability vary by employer.

  • Which Pennsylvania cities have professional job opportunities?question toggle

    Opportunities may be available in Philadelphia, Pittsburgh, Harrisburg, Allentown, Lancaster, and other areas across the state. Check each listing for its specific location and work arrangement.

  • Are these Pennsylvania jobs vetted?question toggle

    Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review individual listings for details about the employer, qualifications, responsibilities, and compensation.

  • Can I find remote or hybrid jobs in Pennsylvania?question toggle

    Some employers may offer remote or hybrid arrangements, but availability varies. Check the work-location details in each job listing.