Explore $100K+ Jobs in Pennsylvania

Discover vetted professional opportunities across Pennsylvania with Ladders. Browse jobs with salaries of $100,000 or more, from senior leadership and management roles to specialized positions in technology, healthcare, finance, engineering, and other fields. Whether you’re looking in Philadelphia, Pittsburgh, Harrisburg, or elsewhere in the state, explore openings that match your experience and career goals.

Find opportunities across Pennsylvania

Pennsylvania’s major cities and regional business centers offer a wide range of professional career paths. Search for opportunities in metropolitan areas such as Philadelphia and Pittsburgh, as well as roles in Harrisburg, Allentown, Lancaster, and other communities. Availability varies by employer and location, so review each listing for work location and remote or hybrid details.

Browse senior and specialized roles

Explore positions for experienced professionals, including director, vice president, executive, and other senior-level roles. You can also find specialized opportunities in areas such as technology, healthcare, finance, sales, operations, and engineering. Review job requirements, responsibilities, and compensation information to identify roles suited to your expertise.

Make your next career move

Use Ladders to explore vetted jobs paying $100,000 or more in Pennsylvania. Compare opportunities, focus your search by location and profession, and apply to positions aligned with your qualifications. New listings may be added as employers seek experienced talent across the state.

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$170K - $220K *

Accelerate your career by driving sales growth through strategic partnerships and innovative solutions in the cloud computing space. Collaborate with teams to achieve targets and enhance customer sati...

United StatesRemote

Today

  •   Less than 5 years exp.  •   Information Technology

$133K - $209K *

Join a dynamic IT team as you safeguard cloud infrastructure, enhance security measures, and lead incident response efforts. Your expertise will drive continuous improvement and ensure robust protecti...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$100K - $120K *

Drive your career with us as you craft compelling technical proposals for aerospace projects. Collaborate with experts to deliver innovative solutions and elevate your writing skills in a dynamic, mis...

Pittsburgh, PARemote

3 weeks ago

  •   5 - 7 years exp.  •   Aerospace & Defense

$79K - $147K *

Elevate your career by contributing to critical systems engineering projects for the U.S. Air Force. Collaborate with a dynamic team to design, analyze, and document software systems, ensuring high-qu...

3 weeks ago

  •   Less than 5 years exp.  •   Aerospace & Defense

$79K - $147K *

Join a dynamic team as you leverage your expertise in systems integration and testing to support critical defense programs. Collaborate on software engineering tasks, enhance operational capabilities...

3 weeks ago

  •   Less than 5 years exp.  •   Aerospace & Defense

$79K - $147K *

Take ownership of systems engineering tasks, developing requirements and models while collaborating with stakeholders to deliver integrated solutions for strategic defense technologies. Support verifi...

3 weeks ago

  •   Less than 5 years exp.  •   Aerospace & Defense

$79K - $147K *

Engage with a dynamic team to develop innovative systems solutions, ensuring technical excellence and strategic defense capabilities. Collaborate across disciplines to drive requirements and verificat...

3 weeks ago

  •   Less than 5 years exp.  •   Aerospace & Defense

$135K - $160K *

Engineer innovative cloud-native solutions by leading architecture design and implementation. Collaborate with cross-functional teams to drive technical strategies while mentoring talent, ensuring pro...

United StatesRemote

Reposted 4 weeks ago

  •   8 - 10 years exp.  •   Enterprise Technology

$110K - $130K *

Innovate and optimize software solutions that transform construction processes. Collaborate across teams to develop 3D visualization tools, leveraging AI and geospatial data to enhance project managem...

1 week ago

  •   5 - 7 years exp.  •   Enterprise Technology

$130K - $155K *

Drive the architectural vision for AI-led commercial lending modernization, leading a team of engineers to transform legacy systems into innovative solutions while ensuring hands-on involvement throug...

2 weeks ago

  •   8 - 10 years exp.  •   Finance & Insurance

$140K - $187K *

Innovate the future of AI security by designing and implementing robust defenses against adversarial threats, ensuring the integrity of AI systems while fostering innovation and collaboration across c...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$95K - $115K *

Shape the future of mission-critical hardware by leading cross-discipline engineering teams. Drive product development of high-power RF solutions while ensuring compliance, managing risks, and meeting...

Yesterday

  •   5 - 7 years exp.  •   Aerospace & Defense

$186K - $221K *

Shape the future of client engagement by leading high-value sales pursuits, orchestrating teams, and driving innovative strategies that elevate our competitive edge and ensure client satisfaction...

Reposted 2 weeks ago

  •   Less than 5 years exp.  •   Business Services

$186K - $221K *

Champion growth by leading high-value sales pursuits, shaping strategies, and driving client engagement. Collaborate with teams to deliver innovative solutions and influence market offerings while ens...

2 weeks ago

  •   Less than 5 years exp.  •   Business Services

$69K - $141K *

Accelerate progress at the forefront of DevSecOps engineering, collaborating with a talented team to streamline software delivery and bolster security, with opportunities for growth and skill enhancem...

Reposted 2 weeks ago

  •   Less than 5 years exp.  •   Information Technology

$180K - $200K *

Reimagine security engineering leadership by guiding strategic initiatives across cloud and infrastructure security, enhancing detection engineering, and fostering collaboration to protect a multi-clo...

RemoteRemote

Reposted 2 days ago

  •   8 - 10 years exp.  •   Real Estate & Construction

$165K - $187K *

Lead the charge in designing innovative rail transit track solutions, managing complex projects from conception to completion while ensuring compliance with industry standards and fostering strong cli...

Yesterday

  •   8 - 10 years exp.  •   Transportation

$120K - $145K *

Help us secure our cloud-based healthcare platforms by designing and implementing robust security solutions. This role demands expertise in cloud security, AI/ML protection, and compliance with indust...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$85K - $95K *

Collaborate with a dynamic team as a Structural BIM Technician to create detailed models, streamline design processes, and enhance interoperability in building projects, while upholding high-quality s...

United StatesRemote

Reposted 2 weeks ago

  •   5 - 7 years exp.  •   Technical Services

$150K - $180K *

Innovate solutions as a Global Resolution Engineer, tackling complex escalations across diverse customer environments. Collaborate with teams to enhance product reliability and drive proactive improve...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Information Technology

$125K - $145K *

Lead the charge in building impactful software features that enhance educators' management of English Learner programs, taking ownership from design to operation in a full-stack environment utilizing...

RemoteRemote

Reposted 1 week ago

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$110K - $130K *

Champion complex network installation projects by leading teams, mentoring technicians, and ensuring high-quality service delivery. Collaborate with project managers and customers to meet objectives w...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$160K - $205K *

Champion innovative Salesforce solutions by leading architecture and integration efforts. Collaborate with stakeholders to enhance CRM capabilities, ensuring secure and efficient digital services whil...

United StatesRemote

4 days ago

  •   8 - 10 years exp.  •   Information Technology

$156K - $187K *

Transform the data landscape by designing and implementing robust integration solutions. Collaborate with cross-functional teams to enhance analytics infrastructure, ensuring seamless data flow and go...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Finance & Insurance

$162K - $211K *

Join a dynamic engineering team to build and maintain production platforms, driving architectural decisions and mentoring junior engineers while ensuring system reliability and integration with IT Sec...

United StatesRemote

3 weeks ago

  •   8 - 10 years exp.  •   Healthcare

Frequently Asked Questions (FAQ)

  • What types of $100K+ jobs can I find in Pennsylvania?question toggle

    Pennsylvania listings may include senior management, executive, and specialized professional roles in fields such as technology, healthcare, finance, sales, operations, and engineering. Roles and availability vary by employer.

  • Which Pennsylvania cities have professional job opportunities?question toggle

    Opportunities may be available in Philadelphia, Pittsburgh, Harrisburg, Allentown, Lancaster, and other areas across the state. Check each listing for its specific location and work arrangement.

  • Are these Pennsylvania jobs vetted?question toggle

    Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review individual listings for details about the employer, qualifications, responsibilities, and compensation.

  • Can I find remote or hybrid jobs in Pennsylvania?question toggle

    Some employers may offer remote or hybrid arrangements, but availability varies. Check the work-location details in each job listing.