Explore $100K+ Jobs in Pennsylvania

Discover vetted professional opportunities across Pennsylvania with Ladders. Browse jobs with salaries of $100,000 or more, from senior leadership and management roles to specialized positions in technology, healthcare, finance, engineering, and other fields. Whether you’re looking in Philadelphia, Pittsburgh, Harrisburg, or elsewhere in the state, explore openings that match your experience and career goals.

Find opportunities across Pennsylvania

Pennsylvania’s major cities and regional business centers offer a wide range of professional career paths. Search for opportunities in metropolitan areas such as Philadelphia and Pittsburgh, as well as roles in Harrisburg, Allentown, Lancaster, and other communities. Availability varies by employer and location, so review each listing for work location and remote or hybrid details.

Browse senior and specialized roles

Explore positions for experienced professionals, including director, vice president, executive, and other senior-level roles. You can also find specialized opportunities in areas such as technology, healthcare, finance, sales, operations, and engineering. Review job requirements, responsibilities, and compensation information to identify roles suited to your expertise.

Make your next career move

Use Ladders to explore vetted jobs paying $100,000 or more in Pennsylvania. Compare opportunities, focus your search by location and profession, and apply to positions aligned with your qualifications. New listings may be added as employers seek experienced talent across the state.

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$220K - $300K *

Accelerate cybersecurity innovation by designing robust solutions, leading client engagements, and fostering strategic collaborations. Leverage your extensive experience to tackle complex security cha...

United StatesRemote

4 weeks ago

  •   8 - 10 years exp.  •   Information Technology

$110K - $130K *

Elevate your career by designing and automating GRC systems that enhance compliance visibility and efficiency. Collaborate with cross-functional teams to implement AI-powered solutions, ensuring strea...

United StatesRemote

Reposted today

  •   Less than 5 years exp.  •   Enterprise Technology

$150K - $180K *

Drive the future of technical sales leadership by managing a team of Solutions Engineers, enhancing enterprise adoption of cutting-edge technologies, and ensuring technical wins through strategic part...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Enterprise Technology

$98K - $206K *

Join a dynamic team as you design and implement Azure IaaS solutions, ensuring operational support and service delivery for a government customer. Contribute to system modernization and enhance servic...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$110K - $130K *

Join a team that's redefining endpoint management by designing and optimizing Active Directory, Group Policy, and Intune solutions for a global organization, ensuring seamless integration and user pro...

Pennsylvania, USRemote

3 weeks ago

  •   15+ years exp.  •   Pharmaceuticals & Biotech

$145K - $269K *

Drive your career forward by leading the integration and delivery of advanced ground systems for a next-gen MILSATCOM program. Collaborate with cross-functional teams to ensure successful system perfo...

3 weeks ago

  •   Less than 5 years exp.  •   Aerospace & Defense

$174K - $235K *

Unlock potential by building and maintaining capacity forecasts to guide investment decisions. Collaborate across teams to ensure timely delivery and optimize resource allocation while mentoring peers...

RemoteRemote

1 week ago

  •   8 - 10 years exp.  •   Telecommunications & Hardware

$134K - $179K *

Advance your career by providing technical expertise in Energy-as-a-Service projects, focusing on energy conservation measures and optimizing system performance across complex, multi-building environm...

2 weeks ago

  •   8 - 10 years exp.  •   Business Services

$110K - $130K *

Join a team that's driving innovation in automotive connectivity while leading strategic programs for major OEMs. Your expertise will ensure timely project delivery, enhance customer relations, and fo...

Reposted 2 days ago

  •   8 - 10 years exp.  •   Business Services

$150K - $180K *

Lead the product vision and strategy for a cutting-edge cloud service, shaping capabilities and defining AI-driven insights while collaborating with engineering and operations teams to ensure market a...

United StatesRemote

Yesterday

  •   8 - 10 years exp.  •   Information Technology

$71K - $97K *

Optimize the reliability and performance of automated warehouse systems. Engage in hands-on troubleshooting, maintenance, and technical execution to ensure optimal system uptime in a fast-paced produc...

1 month ago

  •   Less than 5 years exp.  •   Manufacturing & Automotive

$135K - $185K *

Transform enterprise architecture by defining our technology strategy, guiding scalable solutions, and leading modernization initiatives that align with business goals. Thrive in a role that fosters i...

RemoteRemote

Reposted 1 week ago

  •   8 - 10 years exp.  •   Transportation

$115K - $125K *

Take ownership of RF shielding projects, leading design and development of SCIFs and EMI/RFI solutions. Collaborate with cross-functional teams to ensure compliance with federal standards while optimi...

4 weeks ago

  •   8 - 10 years exp.  •   Aerospace & Defense

$63K - $177K *

Champion application security and DevSecOps by modernizing legacy systems to cloud-first models. Enhance resilience against threats through automation and AI, ensuring secure, scalable deployments acr...

2 weeks ago

  •   Less than 5 years exp.  •   Business Services

$130K - $155K *

Join a team that's shaping the future of engineering platforms by owning the strategy and outcomes for cloud hosting and developer tools. Collaborate across teams to enhance delivery, optimize costs...

1 week ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$80K - $95K *

Contribute to innovative software solutions that enhance business efficiency, streamline decision-making, and support strategic objectives. Collaborate with teams to design, implement, and maintain im...

Reposted 1 week ago

  •   Less than 5 years exp.  •   Aerospace & Defense

$150K - $180K *

Empower security operations and engineering to enhance threat detection, incident response, and prevention. Collaborate with cross-functional teams to scale security measures as the organization grows...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Enterprise Technology

$185K - $235K *

Transform engineering practices by leading AI Enablement initiatives, enhancing workflows, and driving adoption of AI standards across teams. Collaborate with stakeholders to measure progress and deli...

United StatesRemote

Yesterday

  •   5 - 7 years exp.  •   Energy & Utilities

$140K - $200K *

Shape the future of mixed-signal IC design by leading EDA/CAD efforts. Collaborate with a skilled team to drive innovative solutions from concept to production, ensuring high-performance layouts and t...

Yesterday

  •   5 - 7 years exp.  •   Retail & Consumer Goods

$102K - $190K *

Pioneer the future of endpoint security by leading a dynamic engineering team, ensuring operational excellence, and driving innovative capabilities to protect enterprise assets while aligning with bus...

RemoteRemote

3 days ago

  •   5 - 7 years exp.  •   Healthcare

$181K - $301K *

Elevate our cyber defense capabilities by architecting advanced detection and response systems. Lead cross-functional initiatives, influence technical strategy, and enhance security measures to protec...

United StatesRemote

2 weeks ago

  •   11 - 15 years exp.  •   Healthcare

$110K - $130K *

Architect solutions to enhance DevOps teams' security by managing pre-sales technical support, conducting product demos, and serving as a subject matter expert in CI/CD integrations and workflows. Eng...

United StatesRemote

Reposted 3 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$150K - $180K *

Join a team that's redefining software development leadership by driving strategic initiatives, enhancing team capabilities, and ensuring high-quality delivery across platforms. Lead a talented team t...

3 weeks ago

  •   11 - 15 years exp.  •   Transportation

$113K - $147K *

Pioneer innovative solutions as a Microsoft Power Platform Architect, leading enterprise-grade design and implementation. Collaborate with stakeholders to enhance efficiency, automate processes, and d...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Business Services

$200K - $240K *

Drive strategic growth initiatives for Navy & Marine Corps, leading business development efforts and fostering partnerships to enhance tactical networking solutions across diverse operational domains...

United StatesRemote

1 week ago

  •   11 - 15 years exp.  •   Information Technology

Frequently Asked Questions (FAQ)

  • What types of $100K+ jobs can I find in Pennsylvania?question toggle

    Pennsylvania listings may include senior management, executive, and specialized professional roles in fields such as technology, healthcare, finance, sales, operations, and engineering. Roles and availability vary by employer.

  • Which Pennsylvania cities have professional job opportunities?question toggle

    Opportunities may be available in Philadelphia, Pittsburgh, Harrisburg, Allentown, Lancaster, and other areas across the state. Check each listing for its specific location and work arrangement.

  • Are these Pennsylvania jobs vetted?question toggle

    Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review individual listings for details about the employer, qualifications, responsibilities, and compensation.

  • Can I find remote or hybrid jobs in Pennsylvania?question toggle

    Some employers may offer remote or hybrid arrangements, but availability varies. Check the work-location details in each job listing.