Explore $100K+ Jobs in Pennsylvania

Discover vetted professional opportunities across Pennsylvania with Ladders. Browse jobs with salaries of $100,000 or more, from senior leadership and management roles to specialized positions in technology, healthcare, finance, engineering, and other fields. Whether you’re looking in Philadelphia, Pittsburgh, Harrisburg, or elsewhere in the state, explore openings that match your experience and career goals.

Find opportunities across Pennsylvania

Pennsylvania’s major cities and regional business centers offer a wide range of professional career paths. Search for opportunities in metropolitan areas such as Philadelphia and Pittsburgh, as well as roles in Harrisburg, Allentown, Lancaster, and other communities. Availability varies by employer and location, so review each listing for work location and remote or hybrid details.

Browse senior and specialized roles

Explore positions for experienced professionals, including director, vice president, executive, and other senior-level roles. You can also find specialized opportunities in areas such as technology, healthcare, finance, sales, operations, and engineering. Review job requirements, responsibilities, and compensation information to identify roles suited to your expertise.

Make your next career move

Use Ladders to explore vetted jobs paying $100,000 or more in Pennsylvania. Compare opportunities, focus your search by location and profession, and apply to positions aligned with your qualifications. New listings may be added as employers seek experienced talent across the state.

Remote
caret down
Compensation
caret down
Position Level
caret down
Time Posted
caret down
Industries
caret down
Locations
caret down
More
1
caret down

Sort By: Relevance

$125K - $150K *

Elevate enterprise architecture by serving as a senior technical authority, guiding the development of architectural visions and frameworks, and advising on technology adoption and modernization initi...

1 week ago

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$108K - $181K *

Partner with us to drive growth in the data center market by building strategic relationships with hyperscalers and colocation providers, shaping innovative solutions, and leading negotiations to secu...

United StatesRemote

6 days ago

  •   5 - 7 years exp.  •   Business Services

$120K - $145K *

Elevate security standards by leading bug bounty programs, conducting audits, and enhancing software supply chain security. Collaborate across teams to build innovative tools that protect users and en...

RemoteRemote

1 week ago

  •   Less than 5 years exp.  •   Information Technology

$128K - $225K *

Unlock potential by leading cloud engineering strategy and product development. Oversee a high-performing team to deliver secure, scalable cloud solutions across multiple providers, ensuring alignment...

United StatesRemote

2 days ago

  •   8 - 10 years exp.  •   Information Technology

$160K - $180K *

Join us to lead our accounting operations, ensuring accuracy and scalability. Drive financial reporting, audits, and team development while applying your technical expertise in a dynamic, multi-channe...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Information Technology

$125K - $150K *

Transform business workflows by developing and maintaining applications that enhance productivity and information sharing across teams. Collaborate with IT and business units to deliver innovative sol...

United StatesRemote

Reposted today

  •   Less than 5 years exp.  •   Technical Services

$185K - $272K *

Shape the future of technical training and enablement, driving market awareness and engagement. Collaborate across teams to deliver impactful educational content while representing innovative technolo...

United StatesRemote

4 weeks ago

  •   11 - 15 years exp.  •   Information Technology

$69K - $141K *

Join a team that's shaping the future of space technology! As a Software Engineer, you'll develop mission-critical software, collaborate with experts, and enhance your skills while delivering impactfu...

2 days ago

  •   Less than 5 years exp.  •   Information Technology

$69K - $141K *

Elevate your software engineering career by developing mission-critical space system software. Collaborate with senior engineers, implement features independently, and deepen your technical skills in...

2 days ago

  •   Less than 5 years exp.  •   Information Technology

$63K - $129K *

Elevate your career by joining a dynamic Agile team to design, develop, and implement innovative software solutions. Collaborate closely with stakeholders to deliver high-quality products while mentor...

United StatesRemote

2 days ago

  •   Less than 5 years exp.  •   Information Technology

$69K - $141K *

Join a dynamic team to develop mission-critical software for space systems. Leverage your 3+ years of experience to implement features, collaborate with experts, and enhance your skills in a supportiv...

3 days ago

  •   Less than 5 years exp.  •   Information Technology

$121K - $195K *

Transform the future of design implementation by driving place and route activities, ensuring timing closure, and optimizing performance metrics. Collaborate globally to achieve right-first-time silic...

1 week ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$90K - $110K *

Join a dynamic team as you drive growth by designing tailored software solutions for schools. Leverage your technical expertise to engage clients, deliver impactful demos, and collaborate with cross-f...

United StatesRemote

Reposted 2 weeks ago

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$119K - $179K *

Support the integration and harmonization of clinical data by designing FHIR-compliant models and pipelines, ensuring data accuracy and usability for patient care and research initiatives across the o...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$90K - $110K *

Empower our global technology infrastructure by managing and optimizing IT systems, cloud services, and cybersecurity initiatives. Collaborate with a talented team to drive digital transformation and...

2 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$110K - $130K *

Shape global finance solutions by leading Infor M3 architecture, ensuring alignment with business priorities while minimizing customization. Collaborate across teams to deliver scalable, supportable s...

2 days ago

  •   Less than 5 years exp.  •   Information Technology

$145K - $175K *

Advance your career by overseeing Oracle system integrations across multiple customer engagements. Collaborate with teams to enhance platform ownership and provide pre-sales support, ensuring seamless...

United StatesRemote

1 week ago

  •   11 - 15 years exp.  •   Enterprise Technology

$117K - $176K *

Drive innovation by developing and supporting ERP solutions that optimize business operations. Collaborate with cross-functional teams to enhance Manufacturing and Repair processes, ensuring effective...

United StatesRemote

Reposted today

  •   5 - 7 years exp.  •   Aerospace & Defense

$60K - $110K *

Elevate telecommunications network capabilities by designing and managing complex systems. Collaborate with cross-functional teams to implement voice, data, and wireless solutions, ensuring seamless c...

4 weeks ago

  •   Less than 5 years exp.  •   Information Technology

$60K - $110K *

Drive the design and management of telecommunications networks, ensuring effective support for voice, data, and video services. Collaborate with cross-functional teams to implement solutions and maint...

4 weeks ago

  •   Less than 5 years exp.  •   Information Technology

$160K - $185K *

Join us to lead a dynamic team of DevOps, MLOps, and DataOps engineers, driving innovation across our multi-cloud platform. You'll mentor talent, set technical standards, and remain hands-on in engine...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Information Technology

$101K - $168K *

Unlock potential by leading complex civil engineering projects across North America. Collaborate with multidisciplinary teams, mentor junior engineers, and deliver innovative solutions from planning t...

2 weeks ago

  •   8 - 10 years exp.  •   Real Estate & Construction

$60K - $110K *

Shape your career with a key role in telecommunications network design and management. Collaborate with professionals to analyze, plan, and implement complex network solutions supporting voice, data...

4 weeks ago

  •   Less than 5 years exp.  •   Information Technology

$138K - $198K *

Pioneer innovative Silicon Photonics solutions by leading full product design cycles, collaborating on opto-electronic integration, and driving rapid iterations to deliver next-gen products in a fast...

5 days ago

  •   Less than 5 years exp.  •   Telecommunications & Hardware

$206K - $283K *

Champion network security transformation by providing expert guidance in Zero Trust and cloud solutions. Collaborate with sales teams to architect tailored security solutions, ensuring customer succes...

2 weeks ago

  •   5 - 7 years exp.  •   Enterprise Technology

Frequently Asked Questions (FAQ)

  • What types of $100K+ jobs can I find in Pennsylvania?question toggle

    Pennsylvania listings may include senior management, executive, and specialized professional roles in fields such as technology, healthcare, finance, sales, operations, and engineering. Roles and availability vary by employer.

  • Which Pennsylvania cities have professional job opportunities?question toggle

    Opportunities may be available in Philadelphia, Pittsburgh, Harrisburg, Allentown, Lancaster, and other areas across the state. Check each listing for its specific location and work arrangement.

  • Are these Pennsylvania jobs vetted?question toggle

    Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review individual listings for details about the employer, qualifications, responsibilities, and compensation.

  • Can I find remote or hybrid jobs in Pennsylvania?question toggle

    Some employers may offer remote or hybrid arrangements, but availability varies. Check the work-location details in each job listing.