Explore $100K+ Jobs in Pennsylvania

Discover vetted professional opportunities across Pennsylvania with Ladders. Browse jobs with salaries of $100,000 or more, from senior leadership and management roles to specialized positions in technology, healthcare, finance, engineering, and other fields. Whether you’re looking in Philadelphia, Pittsburgh, Harrisburg, or elsewhere in the state, explore openings that match your experience and career goals.

Find opportunities across Pennsylvania

Pennsylvania’s major cities and regional business centers offer a wide range of professional career paths. Search for opportunities in metropolitan areas such as Philadelphia and Pittsburgh, as well as roles in Harrisburg, Allentown, Lancaster, and other communities. Availability varies by employer and location, so review each listing for work location and remote or hybrid details.

Browse senior and specialized roles

Explore positions for experienced professionals, including director, vice president, executive, and other senior-level roles. You can also find specialized opportunities in areas such as technology, healthcare, finance, sales, operations, and engineering. Review job requirements, responsibilities, and compensation information to identify roles suited to your expertise.

Make your next career move

Use Ladders to explore vetted jobs paying $100,000 or more in Pennsylvania. Compare opportunities, focus your search by location and profession, and apply to positions aligned with your qualifications. New listings may be added as employers seek experienced talent across the state.

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$120K - $145K *

Transform cloud infrastructure for higher education products by designing, building, and operating AWS and Azure environments. Collaborate with teams to enhance reliability, automate processes, and me...

United StatesRemote

3 weeks ago

  •   8 - 10 years exp.  •   Education, Government & Non-Profit

$74K - $113K *

Lead the charge in innovative architectural design for diverse power-related projects. Collaborate with multidisciplinary teams to deliver cutting-edge solutions that meet client needs while ensuring...

United StatesRemote

Yesterday

  •   Less than 5 years exp.  •   Technical Services

$160K - $200K *

Elevate the technical architecture vision and execution across a product portfolio, driving the transition to a scalable, cloud-native SaaS environment while integrating AI, data, and security. Collab...

United StatesRemote

3 weeks ago

  •   11 - 15 years exp.  •   Business Services

$119K - $175K *

Drive complex security initiatives, mentor engineers, and lead investigations into high-impact incidents, focusing on AI/LLM security posture and compliance across multiple domains...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$135K - $160K *

Join a team that's redefining data architecture by leading innovative modeling and integration initiatives. Collaborate with AI Engineers to create scalable datasets and optimize performance in a mult...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Information Technology

$150K - $180K *

Transform enterprise AI solutions by designing and implementing Multi-Agentic AI architectures. Leverage expertise in Generative AI, cloud technologies, and governance to lead projects from proof of c...

United StatesRemote

2 weeks ago

  •   11 - 15 years exp.  •   Information Technology

$104K - $149K *

Join a team that's redefining locomotive communication networks. As a Senior Embedded Network Design Engineer, you'll lead the architecture and validation of robust systems, collaborating across funct...

1 week ago

  •   8 - 10 years exp.  •   Transportation

$87K - $135K *

Drive your career forward by leading systems engineering for a cloud-based enterprise system. Engage in architecture development, integration, and modernization efforts while ensuring security and ope...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Enterprise Technology

$125K - $140K *

Join a team that's dedicated to transforming supply chain solutions through innovative Oracle OTM and GTM implementations, ensuring timely delivery and optimal client satisfaction while enhancing your...

United StatesRemote

6 days ago

  •   Less than 5 years exp.  •   Transportation

$61K - $141K *

Drive automation solutions by collaborating with cross-functional teams to enhance CI/CD pipelines and manage infrastructure, ensuring seamless deployment and operational excellence in a dynamic envir...

5 days ago

  •   Less than 5 years exp.  •   Business Services

$61K - $141K *

Tackle automation challenges by developing solutions for system infrastructure and applications. Collaborate with cross-functional teams to enhance CI/CD pipelines and support critical naval platforms...

1 week ago

  •   Less than 5 years exp.  •   Business Services

$125K - $150K *

Elevate data architecture by leading design and governance for a critical modernization program, ensuring secure, scalable solutions in AWS GovCloud while collaborating with diverse stakeholders to ma...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Enterprise Technology

$120K - $145K *

Join us to enhance the security posture of our production platform. As an Infrastructure Security Engineer, you'll drive remediation efforts, build security frameworks, and collaborate with teams to p...

RemoteRemote

6 days ago

  •   5 - 7 years exp.  •   Information Technology

$135K - $160K *

Lead the design and implementation of complex Salesforce solutions in a multi-org federal environment. Drive modernization efforts and ensure compliance while providing technical leadership and mentor...

United StatesRemote

6 days ago

  •   8 - 10 years exp.  •   Business Services

$160K - $200K *

Elevate your career as a Principal Technologist, leading AI compute infrastructure solutions in pre-sales. Collaborate with top-tier clients, drive innovative designs, and influence strategic engageme...

RemoteRemote

5 days ago

  •   11 - 15 years exp.  •   Enterprise Technology

$132K - $261K *

Champion client-focused digital transformation by leveraging AI and Adobe technologies. Lead complex migrations, architect scalable solutions, and drive innovation to deliver measurable business value...

Today

  •   8 - 10 years exp.  •   Business Services

$132K - $261K *

Drive client-focused digital transformation by leveraging AI and Adobe technologies. Lead complex migrations, architect scalable solutions, and ensure measurable business value while managing cross-fu...

Today

  •   8 - 10 years exp.  •   Business Services

$130K - $160K *

Lead the engineering of cutting-edge SIEM and SOAR platforms while advising clients on enhancing their security posture. Your expertise will shape customer onboarding and service design, ensuring effe...

United StatesRemote

Reposted 4 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$150K - $200K *

Unlock potential by defining and guiding enterprise architecture, integrating cloud, infrastructure, and security to support business priorities. Lead modernization efforts and influence cross-functio...

United StatesRemote

5 days ago

  •   11 - 15 years exp.  •   Healthcare

$103K - $134K *

Lead strategic business development initiatives, fostering partnerships and driving sales growth. Collaborate across teams to achieve revenue targets while enhancing client relationships and market pr...

Today

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$103K - $134K *

Drive your career with strategic leadership in business development, fostering partnerships and managing customer relationships to achieve sales targets while enhancing brand presence and market share...

Today

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$120K - $145K *

Champion a transformative shift from legacy warehouse systems to Manhattan Active Warehouse Management, leading strategy, implementation, and integration across multiple sites to enhance efficiency an...

United StatesRemote

4 weeks ago

  •   8 - 10 years exp.  •   Transportation

$80K - $95K *

Partner with us to enhance our security posture by managing risks and implementing solutions across cloud environments, applications, and CI/CD pipelines. Ideal for adaptable security enthusiasts look...

4 weeks ago

  •   Less than 5 years exp.  •   Finance & Insurance

$160K - $200K *

Elevate technology leadership by shaping enterprise transformation strategies, building executive relationships, and driving market presence. Collaborate across teams to connect technology investments...

United StatesRemote

3 weeks ago

  •   8 - 10 years exp.  •   Energy & Utilities

$150K - $210K *

Transform Oracle Cloud ERP solutions by leading technical architecture and ensuring quality. Collaborate with teams to drive design decisions and deliver successful implementations while mentoring oth...

United StatesRemote

Today

  •   8 - 10 years exp.  •   Enterprise Technology

Frequently Asked Questions (FAQ)

  • What types of $100K+ jobs can I find in Pennsylvania?question toggle

    Pennsylvania listings may include senior management, executive, and specialized professional roles in fields such as technology, healthcare, finance, sales, operations, and engineering. Roles and availability vary by employer.

  • Which Pennsylvania cities have professional job opportunities?question toggle

    Opportunities may be available in Philadelphia, Pittsburgh, Harrisburg, Allentown, Lancaster, and other areas across the state. Check each listing for its specific location and work arrangement.

  • Are these Pennsylvania jobs vetted?question toggle

    Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review individual listings for details about the employer, qualifications, responsibilities, and compensation.

  • Can I find remote or hybrid jobs in Pennsylvania?question toggle

    Some employers may offer remote or hybrid arrangements, but availability varies. Check the work-location details in each job listing.