Explore $100K+ Jobs in Ohio

Discover professional opportunities across Ohio with Ladders. Browse vetted jobs with salaries of $100,000 or more, from leadership and technology roles to positions in finance, healthcare, engineering, and operations. Whether you’re considering a move to a major city or looking for opportunities closer to home, explore roles that match your experience and career goals.

Where to Find High-Paying Jobs in Ohio

Ohio’s job market spans major metropolitan areas and growing regional economies. Explore opportunities in Columbus, Cleveland, Cincinnati, and other communities throughout the state. Employers across industries seek experienced professionals for roles in corporate leadership, technology, healthcare, manufacturing, financial services, and more. Available positions and compensation vary by employer, location, and qualifications.

Industries and Career Paths

Ohio offers career possibilities across established and emerging sectors. Depending on your background, you may find senior-level opportunities in business management, software and information technology, healthcare administration, engineering, supply chain, sales, and finance. Use Ladders to search current listings and identify roles suited to your skills and professional experience.

Find the Right Ohio Opportunity

Make your search more focused by filtering listings by location, job title, industry, and other preferences. Review each posting for its responsibilities, requirements, and compensation details, then tailor your application to highlight relevant accomplishments. New opportunities are added over time, so check back regularly for the latest $100K+ jobs in Ohio.

Remote
caret down
Compensation
caret down
Position Level
caret down
Time Posted
caret down
Industries
caret down
Locations
caret down
More
1
caret down

$119K - $187K *

Help us develop standardized internet network solutions through innovation and automation. As a key leader, you'll manage complex issues and ensure quality control, transforming how we deliver network...

Reposted 4 days ago

  •   5 - 7 years exp.  •   Finance & Insurance

$170K - $210K *

Partner with us to redefine client solutions through technical expertise in product architecture. Leverage AI tools to create scalable prototypes, engaging deeply with cross-functional teams to delive...

US-AnywhereRemote

4 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$110K - $130K *

Lead the charge in optimizing our global hosting platforms, ensuring engineering excellence and proactive improvement. Collaborate across teams to enhance lifecycle management, support projects, and d...

Reposted 2 weeks ago

  •   8 - 10 years exp.  •   Manufacturing & Automotive

$130K - $160K *

Engage in advanced security operations, implementing and monitoring robust measures to protect systems and networks. Collaborate on multiple projects, leveraging cutting-edge technology to enhance sec...

US-AnywhereRemote

4 days ago

  •   5 - 7 years exp.  •   Information Technology

$95K - $115K *

Develop cutting-edge RF systems and components to enhance communication technologies. Collaborate with teams on design, testing, and optimization while ensuring compliance with industry standards and...

Reposted 2 weeks ago

  •   Less than 5 years exp.  •   Telecommunications & Hardware

$150K - $180K *

Invent and evolve architectural strategies for cloud-native AI platforms at scale. Lead design, deployment, and infrastructure excellence, driving innovation while mentoring teams and shaping technica...

US-AnywhereRemote

3 weeks ago

  •   8 - 10 years exp.  •   Finance & Insurance

$150K - $180K *

Empower enterprise transformation by owning the architecture of large-scale ERP initiatives. Lead integration, data flows, and roadmap development while ensuring alignment with business goals and ente...

3 days ago

  •   11 - 15 years exp.  •   Food & Beverages

$150K - $160K *

Partner with us to shape the quality strategy for a leading exam development platform. Leverage your expertise to guide multiple Agile teams, enhance automation practices, and ensure high standards ac...

US-AnywhereRemote

3 days ago

  •   8 - 10 years exp.  •   Education, Government & Non-Profit

$106K - $143K *

Transform platforms by administering leading AI tools, optimizing usage, and ensuring compliance. Collaborate across teams to enhance AI workflows, enabling safe and effective adoption of innovative t...

US-AnywhereRemote

4 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$100K - $120K *

Lead and manage complex data center projects, ensuring alignment with client goals and technical standards. Drive innovation and team development while fostering strong client relationships and delive...

2 weeks ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$150K - $180K *

Invent and lead the future of enterprise architecture and engineering, driving technical decisions and team management in a dynamic environment. Transform complex systems into scalable, secure solutio...

US-AnywhereRemote

3 weeks ago

  •   8 - 10 years exp.  •   Enterprise Technology

$150K - $185K *

Join a team that's shaping the future of cybersecurity by architecting innovative security programs. Leverage your hands-on expertise to bridge operational security with strategic advisory roles for e...

US-AnywhereRemote

Reposted 3 weeks ago

  •   8 - 10 years exp.  •   Information Technology

$88K - $105K *

Champion cybersecurity excellence by leading on-site operations for control systems, ensuring compliance and resilience. Oversee a team, manage vulnerabilities, and liaise with remote stakeholders to...

3 days ago

  •   Less than 5 years exp.  •   Enterprise Technology

$88K - $105K *

Empower security solutions through expert integration and optimization of IT infrastructures. Analyze complex vulnerabilities, streamline engineering processes, and support secure system lifecycles wh...

4 weeks ago

  •   5 - 7 years exp.  •   Business Services

$150K - $180K *

Grow a dynamic team driving OpenRouter’s provider ecosystem, managing innovations across diverse models and endpoints, ensuring quality and efficiency in inference services for millions of requests da...

US-AnywhereRemote

2 weeks ago

  •   Less than 5 years exp.  •   Information Technology

$110K - $130K *

Drive operational excellence by enhancing reliability and performance of a SaaS platform. Collaborate with development teams to implement automation, incident management, and observability practices...

US-AnywhereRemote

1 week ago

  •   5 - 7 years exp.  •   Enterprise Technology

$160K - $170K *

Join a team that designs scalable and secure technology solutions by collaborating with various stakeholders. You'll lead architecture efforts for enterprise-level projects and shape our Enterprise Ar...

US-AnywhereRemote

Reposted 1 week ago

  •   5 - 7 years exp.  •   Transportation

$172K - $240K *

Join a team that's redefining AI security! As a Principal AI Security Engineer, you'll lead assessments, design controls, and partner with teams to ensure safe AI adoption across the enterprise, drivi...

US-AnywhereRemote

1 week ago

  •   8 - 10 years exp.  •   Information Technology

$152K - $269K *

Explore the forefront of enterprise AI solutions by pioneering innovative architectures and prototypes that solve complex business problems. You will cultivate relationships, drive technical wins, and...

US-AnywhereRemote

Reposted 1 week ago

  •   8 - 10 years exp.  •   Information Technology

$190K - $200K *

Lead the charge in electrical engineering excellence across multiple campuses, ensuring robust design, validation, and energization of critical infrastructure while integrating onsite generation solut...

US-AnywhereRemote

4 days ago

  •   8 - 10 years exp.  •   Information Technology

$145K - $175K *

Join a team that's redefining cloud solutions by architecting innovative CaaS and cloud-native technologies. Collaborate with customers to tackle complex challenges and drive successful cloud transfor...

US-AnywhereRemote

Yesterday

  •   8 - 10 years exp.  •   Manufacturing & Automotive

$110K - $150K *

Drive strategic growth by building partnerships in the oncology sector. Engage with physician practices, support contract negotiations, and enhance service delivery through effective collaboration and...

US-AnywhereRemote

Reposted 3 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$120K - $145K *

Shape the future of our technology by leading solution architecture and development efforts. Drive modernization initiatives, influence technical strategy, and mentor teams while solving complex chall...

4 weeks ago

  •   8 - 10 years exp.  •   Telecommunications & Hardware

$161K - $241K *

Join as the Architecture Operations and Enablement Lead, driving governance and operational excellence within the enterprise architecture function. Collaborate across teams to enhance processes, metri...

US-AnywhereRemote

Today

  •   11 - 15 years exp.  •   Aerospace & Defense

$140K - $150K *

Optimize network security architecture to enhance protection and performance. Collaborate directly with engineering teams to implement designs, manage migrations, and resolve issues, ensuring robust s...

US-AnywhereRemote

Reposted 1 month ago

  •   5 - 7 years exp.  •   Transportation

Frequently Asked Questions (FAQ)

  • What types of $100,000+ jobs can I find in Ohio?question toggle

    Listings may include professional and senior-level roles in fields such as technology, healthcare, finance, engineering, manufacturing, sales, and business operations. Job availability depends on current employer postings.

  • Which Ohio cities have high-paying job opportunities?question toggle

    Explore listings in Columbus, Cleveland, Cincinnati, and other Ohio cities and communities. Use location filters to find opportunities in the areas that work for you.

  • How can I search for jobs in Ohio on Ladders?question toggle

    Browse Ohio job listings and narrow your results by location, job title, industry, or other available filters. Check each posting for salary information, qualifications, and application instructions.

  • Are Ohio jobs on Ladders guaranteed to pay at least $100,000?question toggle

    Ladders focuses on professional jobs with salaries of $100,000 or more. Review each listing for its specific compensation details, since pay and eligibility requirements vary by role and employer.