Explore $100K+ Jobs in Ohio

Discover professional opportunities across Ohio with Ladders. Browse vetted jobs with salaries of $100,000 or more, from leadership and technology roles to positions in finance, healthcare, engineering, and operations. Whether you’re considering a move to a major city or looking for opportunities closer to home, explore roles that match your experience and career goals.

Where to Find High-Paying Jobs in Ohio

Ohio’s job market spans major metropolitan areas and growing regional economies. Explore opportunities in Columbus, Cleveland, Cincinnati, and other communities throughout the state. Employers across industries seek experienced professionals for roles in corporate leadership, technology, healthcare, manufacturing, financial services, and more. Available positions and compensation vary by employer, location, and qualifications.

Industries and Career Paths

Ohio offers career possibilities across established and emerging sectors. Depending on your background, you may find senior-level opportunities in business management, software and information technology, healthcare administration, engineering, supply chain, sales, and finance. Use Ladders to search current listings and identify roles suited to your skills and professional experience.

Find the Right Ohio Opportunity

Make your search more focused by filtering listings by location, job title, industry, and other preferences. Review each posting for its responsibilities, requirements, and compensation details, then tailor your application to highlight relevant accomplishments. New opportunities are added over time, so check back regularly for the latest $100K+ jobs in Ohio.

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$235K - $350K *

Empower the future of cybersecurity AI by leading innovative research and development. Collaborate with experts to create advanced systems that enhance defense capabilities and transform security oper...

US-AnywhereRemote

3 days ago

  •   Less than 5 years exp.  •   Information Technology

$154K - $260K *

Join an innovative team to lead and evolve critical Core Infrastructure. Oversee infrastructure strategy, improve operational health, and drive automation to boost performance across a globally distri...

US-AnywhereRemote

Reposted 2 weeks ago

  •   8 - 10 years exp.  •   Enterprise Technology

$95K - $115K *

Join a team that's dedicated to delivering complex NICE solutions for Public Safety. As a hands-on technical lead, you'll manage installations, upgrades, and troubleshooting, ensuring successful imple...

US-AnywhereRemote

1 week ago

  •   Less than 5 years exp.  •   Enterprise Technology

$125K - $150K *

Lead a dynamic team of Solutions Engineers driving technical success and customer engagement. Collaborate with sales and engineering, ensuring high performance and strategic impact throughout the cust...

US-AnywhereRemote

Reposted 3 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$172K - $202K *

Innovate within identity and access management by providing expert insights and strategies to clients on best practices in identity governance, privileged access, and AI tools, enhancing cybersecurity...

US-AnywhereRemote

Reposted 1 week ago

  •   11 - 15 years exp.  •   Business Services

$120K - $145K *

Join a team that's leading innovative ISR and aviation solutions! As a Principal Systems Engineer, you'll manage critical projects, mentor engineers, and ensure excellence in systems integration and v...

Reposted 2 days ago

  •   11 - 15 years exp.  •   Aerospace & Defense

$72K - $111K *

Lead and innovate Tier I service desk operations by supervising agents, optimizing performance, and ensuring exceptional support for external users. Drive shifts performance, manage escalations, and e...

US-AnywhereRemote

2 weeks ago

  •   Less than 5 years exp.  •   Enterprise Technology

$157K - $180K *

Join a team that's driving innovation by building AI-powered tools for a vibrant community of diverse software engineers. You'll blend hands-on engineering with community management to enhance technic...

US-AnywhereRemote

3 days ago

  •   5 - 7 years exp.  •   Enterprise Technology

$180K - $240K *

Champion innovation by leading AI biomarker development to enhance patient outcomes through robust, interpretable models, while streamlining processes from clinical collaboration to regulatory submiss...

US-AnywhereRemote

4 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$108K - $130K *

Partner with us to innovate and deliver high-impact retail solutions. Drive end-to-end execution as a key technical leader, engaging clients while mentoring teams and ensuring top-notch operational de...

2 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$140K - $180K *

Join us to drive financial strategy for GPU capacity and infrastructure. You'll analyze utilization, forecast cash needs, and optimize revenue impact, playing a key role in scaling our operations in a...

US-AnywhereRemote

5 days ago

  •   Less than 5 years exp.  •   Information Technology

$140K - $170K *

Shape the future of healthcare technology by leveraging your expertise to drive sales success. Collaborate with cross-functional teams to deliver tailored solutions, engage customers, and enhance prod...

US-AnywhereRemote

5 days ago

  •   5 - 7 years exp.  •   Healthcare

$100K - $120K *

Join a team that's dedicated to enhancing construction management services, focusing on client needs and market trends. Lead staff development, business strategies, and project delivery while fosterin...

1 week ago

  •   8 - 10 years exp.  •   Real Estate & Construction

$109K - $325K *

Lead the development of an AI agent optimization platform, enhancing engineering velocity through innovative evaluation systems and intelligent orchestration. Collaborate with cross-functional teams t...

US-AnywhereRemote

Today

  •   5 - 7 years exp.  •   Media

$76K - $134K *

Manage strategic initiatives to enhance curriculum and instruction, providing technical support in the field. Collaborate with stakeholders to drive student achievement and resource acquisition, ensur...

1 week ago

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$160K - $213K *

Innovate data architecture strategies and AI solutions, establishing scalable standards across platforms. Collaborate with leaders to define architecture roadmaps that ensure secure, governed, and eff...

US-AnywhereRemote

3 days ago

  •   8 - 10 years exp.  •   Finance & Insurance

$260K - $300K *

Transform product development by ensuring compliance with laws and regulations. Collaborate with cross-functional teams to proactively manage legal risks throughout the product lifecycle, empowering r...

US-AnywhereRemote

3 weeks ago

  •   8 - 10 years exp.  •   Enterprise Technology

$113K - $197K *

Drive innovation in technology architecture by overseeing design, governance, and strategic alignment across IT disciplines, ensuring best-in-class services and solutions for clients and stakeholders...

US-AnywhereRemote

1 week ago

  •   5 - 7 years exp.  •   Healthcare

$200K - $322K *

Lead the charge in driving open source adoption and governance. Manage community infrastructure, contributor pathways, and post-launch plans to ensure sustainable project growth and engagement across...

US-AnywhereRemote

2 weeks ago

  •   11 - 15 years exp.  •   Manufacturing & Automotive

$110K - $130K *

Champion seamless technical integrations by leading end-to-end delivery, troubleshooting, and documentation. Collaborate with customer IT teams to ensure compliance and optimize data flows in a dynami...

US-AnywhereRemote

1 week ago

  •   5 - 7 years exp.  •   Information Technology

$116K - $193K *

Transform interoperability strategies by leading cross-functional teams to enhance EHR capabilities, ensuring alignment with business, clinical, and regulatory objectives while driving measurable outc...

US-AnywhereRemote

2 days ago

  •   5 - 7 years exp.  •   Healthcare

$150K - $220K *

Contribute to corporate security by designing, implementing, and maintaining robust security measures while collaborating with IT, engineering, and business teams to address and mitigate risks across...

US-AnywhereRemote

Reposted 2 weeks ago

  •   5 - 7 years exp.  •   Telecommunications & Hardware

$110K - $130K *

Unlock potential by leading the design and implementation of scalable web applications using Go and TypeScript. Collaborate with teams to leverage cloud technology, ensuring high availability and opti...

Reposted 2 weeks ago

  •   8 - 10 years exp.  •   Enterprise Technology

$100K - $120K *

Join us to lead a dynamic engineering team, overseeing critical infrastructure initiatives while fostering a culture of safety and integrity within a collaborative environment. Make a lasting impact o...

2 weeks ago

  •   5 - 7 years exp.  •   Energy & Utilities

$130K - $160K *

Join our analytics team to extract structured facts from complex documents, ensuring traceability and accuracy. Contribute to a trusted system that supports human review, operating within a secure env...

US-AnywhereRemote

2 weeks ago

  •   Less than 5 years exp.  •   Enterprise Technology

Frequently Asked Questions (FAQ)

  • What types of $100,000+ jobs can I find in Ohio?question toggle

    Listings may include professional and senior-level roles in fields such as technology, healthcare, finance, engineering, manufacturing, sales, and business operations. Job availability depends on current employer postings.

  • Which Ohio cities have high-paying job opportunities?question toggle

    Explore listings in Columbus, Cleveland, Cincinnati, and other Ohio cities and communities. Use location filters to find opportunities in the areas that work for you.

  • How can I search for jobs in Ohio on Ladders?question toggle

    Browse Ohio job listings and narrow your results by location, job title, industry, or other available filters. Check each posting for salary information, qualifications, and application instructions.

  • Are Ohio jobs on Ladders guaranteed to pay at least $100,000?question toggle

    Ladders focuses on professional jobs with salaries of $100,000 or more. Review each listing for its specific compensation details, since pay and eligibility requirements vary by role and employer.