Explore High-Paying Jobs in Missouri

Find your next career opportunity with Missouri jobs paying $100,000 or more on Ladders. Browse vetted professional roles across the state, from major employers in Kansas City and St. Louis to growing organizations in Springfield, Columbia, and other communities. Listings may include opportunities in technology, healthcare, finance, engineering, operations, and executive leadership.

Career Opportunities Across Missouri

Missouri’s diverse economy supports professional careers across industries such as financial services, healthcare, manufacturing, logistics, technology, and agriculture. Whether you’re looking for an established corporate role or a position with a growing organization, explore openings that match your experience, skills, and compensation goals.

Find Roles That Match Your Goals

Use Ladders to discover vetted jobs with salaries of at least $100,000. Review each listing for details about responsibilities, qualifications, location, and compensation, then focus your search on opportunities that align with your career plans. Job availability and salary details vary by employer and role.

Build Your Career in the Show-Me State

From metropolitan career hubs to communities throughout Missouri, high-paying roles can offer different work environments and paths for advancement. Explore current listings and find professional opportunities that fit the way you want to work and grow.

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1,000+

Network Architect Jobs in Missouri

Sort By: Relevance

$90K - $110K *

Drive innovative software solutions by collaborating with a dynamic team. Engage in full-cycle application development, focusing on performance, security, and scalability while utilizing modern practi...

3 weeks ago

  •   Less than 5 years exp.  •   Information Technology

$125K - $145K *

Unlock potential by bridging IT policy and strategy with organizational goals. Manage policy governance for a federal CIO organization, ensuring alignment with federal standards and overseeing a compr...

United StatesRemote

4 days ago

  •   5 - 7 years exp.  •   Information Technology

$95K - $115K *

Engineer customer reliability by providing expert technical support for IoT solutions. Collaborate with teams to resolve issues, enhance documentation, and gather feedback, ensuring a seamless custome...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Information Technology

$95K *

Join a team that's driving growth by managing key Integrator accounts, developing sales strategies, and fostering relationships to exceed corporate goals in the material handling industry...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$100K - $120K *

Champion hardware readiness for customer deployments, ensuring timely delivery and accurate documentation. Collaborate with cross-functional teams to manage escalations, RMAs, and configuration contro...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Information Technology

$189K - $231K *

Innovate and shape the future of AI platforms as a Senior Engineer, designing and building critical subsystems for enterprise Kubernetes environments. Collaborate with customers and mentor engineers t...

United StatesRemote

5 days ago

  •   Less than 5 years exp.  •   Enterprise Technology

$300K - $500K *

Champion innovation by architecting and developing high-performance, real-time trading web apps. Leverage your expertise to enhance user experience and drive product evolution in a dynamic, collaborat...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Finance & Insurance

$100K - $120K *

Empower quality assurance excellence by leading inspections across North America, ensuring critical infrastructure meets project standards. Collaborate with suppliers and teams to mitigate risks and d...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Enterprise Technology

$170K - $185K *

Drive impactful IT program initiatives for Federal and SLED Governments, overseeing planning, execution, and financial management while fostering client relationships and identifying growth opportunit...

United StatesRemote

6 days ago

  •   8 - 10 years exp.  •   Information Technology

$129K - $193K *

Elevate data center operations by overseeing critical infrastructure, managing teams, and driving continuous improvement initiatives while ensuring safety, quality, and optimal performance across mult...

2 weeks ago

  •   5 - 7 years exp.  •   Retail & Consumer Goods

$80K - $95K *

Drive your career with impactful first-line support for flight simulator software, troubleshooting hardware, and collaborating with cross-functional teams to enhance customer experience and resolve te...

Reposted 1 week ago

  •   Less than 5 years exp.  •   Aerospace & Defense

$137K - $231K *

Empower your career by shaping design systems that enhance user experience. Collaborate with teams to build high-quality, interactive UI across platforms, ensuring accessibility and performance while...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Enterprise Technology

$95K - $115K *

Manage and optimize the organization's network infrastructure, ensuring high performance, security, and operational compliance. Lead a team of network professionals, collaborating with IT and business...

Reposted 1 week ago

  •   8 - 10 years exp.  •   Real Estate & Construction

$150K - $180K *

Empower our mission by leading data center and cloud engineering strategies. This hands-on role requires expertise in infrastructure planning, hybrid-cloud architecture, and automation to drive modern...

United StatesRemote

Yesterday

  •   11 - 15 years exp.  •   Information Technology

$80K - $92K *

Drive the resolution of technical support escalations as a key Tier 2 expert, leveraging your skills to troubleshoot issues, foster collaboration within teams, and enhance workflows in a dynamic envir...

RemoteRemote

Reposted 4 days ago

  •   Less than 5 years exp.  •   Technical Services

$85K - $130K *

Champion innovative control systems for industrial solutions, leading design and development projects. Collaborate with teams to ensure products meet market demands while transitioning designs to manu...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$100K - $122K *

Join a team that's redefining DevOps by building and maintaining CI/CD pipelines, automating workflows, and enhancing service delivery in AWS. Collaborate with cross-functional teams to ensure reliabl...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Finance & Insurance

$100K - $150K *

Lead the charge in enhancing infrastructure reliability and automation for large-scale game development projects, collaborating with teams to implement cloud solutions and streamline CI/CD processes...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Consumer Technology

$210K - $250K *

Elevate your career by driving revenue growth and strategic partnerships within a leading Oracle practice. Lead cross-functional teams to enhance client success and market positioning while fostering...

United StatesRemote

1 week ago

  •   11 - 15 years exp.  •   Enterprise Technology

$80K - $100K *

Deliver full-stack development for a federal healthcare application, collaborating with Agile teams to enhance file management capabilities, ensuring secure and efficient file transfers while maintain...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Enterprise Technology

$150K - $160K *

Champion cloud and application security by enhancing AWS practices, collaborating with cross-functional teams, and driving continuous improvement to ensure secure and compliant environments...

United StatesRemote

Reposted 4 days ago

  •   5 - 7 years exp.  •   Enterprise Technology

$150K - $170K *

Transform the content platform by leading hands-on engineering initiatives. Design and implement shared services, ensuring security and stability while mentoring engineers and driving technical excell...

United StatesRemote

Today

  •   11 - 15 years exp.  •   Education, Government & Non-Profit

$80K - $95K *

Transform project execution by leading design and construction initiatives. Manage budgets, timelines, and client expectations while fostering collaboration and ensuring project excellence from start...

5 days ago

  •   5 - 7 years exp.  •   Real Estate & Construction

$138K - $186K *

Unlock your potential as a principal technical leader for enterprise Unix and Linux platforms, driving architecture, automation, and lifecycle management to deliver resilient infrastructure for critic...

United StatesRemote

4 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$180K - $225K *

Transform the claims process by building robust event-driven systems. As a key player, you'll design, implement, and maintain backend services, ensuring reliability and efficiency while mentoring fell...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Business Services

Frequently Asked Questions (FAQ)

  • What types of high-paying jobs can I find in Missouri?question toggle

    Missouri listings may include professional roles in technology, healthcare, finance, engineering, manufacturing, logistics, operations, and executive leadership. Available positions depend on current employer hiring needs.

  • Do Missouri jobs on Ladders pay at least $100,000?question toggle

    Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review the individual listing for its compensation information and requirements.

  • Where in Missouri can I search for jobs?question toggle

    Explore opportunities in cities such as Kansas City, St. Louis, Springfield, and Columbia, as well as other locations across Missouri. Availability varies by role and employer.

  • How can I find a Missouri job that fits my experience?question toggle

    Browse current listings and compare responsibilities, qualifications, location, and compensation with your experience and career goals. Apply to positions that align with your background.