Find your next career opportunity with Missouri jobs paying $100,000 or more on Ladders. Browse vetted professional roles across the state, from major employers in Kansas City and St. Louis to growing organizations in Springfield, Columbia, and other communities. Listings may include opportunities in technology, healthcare, finance, engineering, operations, and executive leadership.
Missouri’s diverse economy supports professional careers across industries such as financial services, healthcare, manufacturing, logistics, technology, and agriculture. Whether you’re looking for an established corporate role or a position with a growing organization, explore openings that match your experience, skills, and compensation goals.
Use Ladders to discover vetted jobs with salaries of at least $100,000. Review each listing for details about responsibilities, qualifications, location, and compensation, then focus your search on opportunities that align with your career plans. Job availability and salary details vary by employer and role.
From metropolitan career hubs to communities throughout Missouri, high-paying roles can offer different work environments and paths for advancement. Explore current listings and find professional opportunities that fit the way you want to work and grow.
$111K - $167K *
Empower your career by leading IT systems development, implementation, and maintenance. Oversee complex networks, ensure security, and drive automation, all while collaborating to enhance operational...
Reposted 3 weeks ago
Systems and Infrastructure Engineer
$80K - $95K *
Unlock potential by designing and maintaining robust enterprise network and server infrastructures. Collaborate with IT teams and stakeholders to enhance performance, security, and reliability for dai...
5 days ago
$100K - $230K *
Grow strategic client relationships in South Texas through solutions-driven sales. Utilize technical expertise to address complex customer needs and expand market share while fostering long-term partn...
Reposted 4 days ago
$110K - $130K *
Develop reliable backend systems and platforms that empower engineers. Own capabilities from design to production, enhance performance, and collaborate across teams to improve developer experience and...
Today
$120K - $145K *
Contribute to the development of a robust Kubernetes control plane, enhancing multi-cloud infrastructure and driving scalable architecture for enterprise-grade cloud services...
4 weeks ago
$165K - $200K *
Deliver exceptional user experiences by refining complex tools into intuitive designs. Collaborate closely with engineers to enhance UX, ensuring our LLM platform meets user needs with responsiveness...
Reposted 4 days ago
OT Cybersecurity and CUI Lead - Lake City Microgrid and CHP
$110K - $130K *
Transform OT cybersecurity and CUI handling for critical infrastructure projects. Collaborate with engineering teams to ensure compliance, secure data exchange, and effective incident response while m...
1 week ago
Project Manager 4 (Project Manager/SRE)
$130K - $165K *
Elevate project management excellence by overseeing operations, developing strategic plans, and collaborating with stakeholders to enhance network security and incident response for the VA's enterpris...
Today
$120K - $145K *
Shape the future of cybersecurity by providing expert guidance and support to clients. Collaborate with cross-functional teams to enhance customer experience and drive adoption of solutions, ensuring...
1 week ago
Lead Software Engineer, AI Platform
$164K - $240K *
Collaborate with cross-functional teams to build AI infrastructure, ensure reliability and security, and guide technical direction while fostering engineer development. Lead innovative projects that e...
Reposted 2 weeks ago
Project Engineer - Solar and Storage
$95K - $115K *
Lead solar resource assessments and performance analytics for utility-scale projects. Engage with clients, optimize energy yield, and enhance methodologies while ensuring operational excellence in sol...
Yesterday
$120K - $145K *
Transform customer data integration strategies by leveraging your expertise to guide clients in optimizing data flow into the Fusion platform, ensuring reliability and value across complex environment...
Today
$66K - $106K *
Shape the future by collaborating with stakeholders to analyze and document system requirements, ensuring clarity and consistency across products while enhancing functionality and user experience in a...
5 days ago
$80K - $102K *
Contribute to the design of user-centric digital products across platforms, collaborating with cross-functional teams to create high-fidelity prototypes and workflows that enhance user experience and...
1 week ago
Staff Engineer - QA Automation
$110K - $130K *
Shape the future of quality assurance by leading automated testing initiatives for cloud-based ERP systems, ensuring seamless integration and performance across various business processes and upgrades...
3 weeks ago
$90K - $110K *
Shape user experiences by designing intuitive interfaces for a cutting-edge security platform. Collaborate with engineers to create impactful visual workflows, leveraging modern technologies to enhanc...
Reposted today
Aviation Technology Program Engineer (Associate Principal, Aviation Technology Engineer)
$141K - $186K *
Transform aviation security by leading multidisciplinary teams, managing client relationships, and ensuring project success in airport technology systems. Leverage 8-10 years of experience to enhance...
3 weeks ago
Aviation Technology Program Engineer (Associate Principal, Aviation Technology Engineer)
$141K - $186K *
Elevate your career by leading technology and security engineering for major aviation projects. Collaborate with clients and multidisciplinary teams to ensure successful project delivery while enhanci...
3 weeks ago
Forward Deployed Engineer (San Francisco)
$130K - $155K *
Unlock potential by driving innovative AI solutions through hands-on engineering and client collaboration. Transform complex business challenges into reliable, production-ready software while enhancin...
Reposted 3 days ago
Linux Web Server Administrator
$110K - $130K *
Transform your career by managing and optimizing Linux web server environments. Leverage your expertise in Apache, Tomcat, and NGINX to enhance performance, security, and reliability in a fully remote...
2 weeks ago
Account Director Senior Large Enterprise Forward Deployed
$126K - $185K *
Lead transformative technology adoption and growth for large enterprise accounts. Drive strategic initiatives, build executive relationships, and deliver measurable outcomes through innovative solutio...
1 week ago
$110K - $130K *
Lead the charge in delivering Microsoft 365 consulting engagements, focusing on SharePoint Online and modern collaboration tools. Drive client relationships, solution design, and governance while ment...
Today
ServiceNow Business Data Analyst
$90K - $189K *
Elevate your career as a ServiceNow Business Analyst, bridging data analysis and IT modernization. Collaborate with stakeholders to optimize workflows and enhance performance outcomes through actionab...
2 weeks ago
$130K - $160K *
Empower the development of mission-critical applications on the ServiceNow platform, collaborating with stakeholders to deliver scalable solutions while ensuring compliance with federal standards and...
2 weeks ago
Senior Partner Success Implementation Engineer
$120K - $145K *
Drive partner success by providing expert technical guidance, leading complex implementations, and mentoring junior engineers. Collaborate cross-functionally to enhance product adoption and ensure opt...
1 week ago
What types of high-paying jobs can I find in Missouri?
Missouri listings may include professional roles in technology, healthcare, finance, engineering, manufacturing, logistics, operations, and executive leadership. Available positions depend on current employer hiring needs.
Do Missouri jobs on Ladders pay at least $100,000?
Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review the individual listing for its compensation information and requirements.
Where in Missouri can I search for jobs?
Explore opportunities in cities such as Kansas City, St. Louis, Springfield, and Columbia, as well as other locations across Missouri. Availability varies by role and employer.
How can I find a Missouri job that fits my experience?
Browse current listings and compare responsibilities, qualifications, location, and compensation with your experience and career goals. Apply to positions that align with your background.