Find your next career opportunity with Missouri jobs paying $100,000 or more on Ladders. Browse vetted professional roles across the state, from major employers in Kansas City and St. Louis to growing organizations in Springfield, Columbia, and other communities. Listings may include opportunities in technology, healthcare, finance, engineering, operations, and executive leadership.
Missouri’s diverse economy supports professional careers across industries such as financial services, healthcare, manufacturing, logistics, technology, and agriculture. Whether you’re looking for an established corporate role or a position with a growing organization, explore openings that match your experience, skills, and compensation goals.
Use Ladders to discover vetted jobs with salaries of at least $100,000. Review each listing for details about responsibilities, qualifications, location, and compensation, then focus your search on opportunities that align with your career plans. Job availability and salary details vary by employer and role.
From metropolitan career hubs to communities throughout Missouri, high-paying roles can offer different work environments and paths for advancement. Explore current listings and find professional opportunities that fit the way you want to work and grow.
Senior Project Manager - Data Center Construction
$115K - $201K *
Explore your potential by leading large-scale data center projects from planning to delivery. Manage budgets, schedules, and stakeholder communication while ensuring quality and safety in critical inf...
2 weeks ago
$88K - $105K *
Accelerate progress at customer success by managing a diverse portfolio, ensuring product adoption, and driving retention through proactive engagement and collaboration with cross-functional teams...
6 days ago
$86K - $137K *
Optimize project outcomes as you manage small to medium-sized initiatives. Collaborate across teams, navigate risks, and ensure timely delivery of quality solutions while enhancing communication and s...
Reposted 1 week ago
$116K - $157K *
Drive program success by leading cross-functional teams in executing IRAD efforts, ensuring alignment with technical, cost, and schedule goals from concept to transition, while fostering collaboration...
Reposted 1 week ago
Director, Distribution Strategy
$172K - $203K *
Empower the distribution strategy by designing and managing rate content across channels, ensuring accurate delivery and partner trust. Collaborate with cross-functional teams to build scalable progra...
2 weeks ago
Senior Embedded Software Engineer
$120K - $145K *
Lead the development of critical firmware for safety-critical systems, collaborating across teams to optimize embedded platforms. Drive best practices and mentor engineers while ensuring reliability a...
5 days ago
$82K - $172K *
Transform complex data ecosystems by leveraging your Elasticsearch expertise to design, optimize, and lead advanced analytics initiatives. Collaborate with cross-functional teams to enhance mission-cr...
Reposted 2 weeks ago
Telecom OSS Reinvention Senior Manager
$122K - $292K *
Advance network operations by leading OSS reinvention initiatives, leveraging AI and automation to modernize environments. Collaborate with clients to define strategies, implement solutions, and drive...
4 weeks ago
$88K - $105K *
Lead product marketing initiatives by crafting compelling messaging and strategies that drive customer engagement and adoption. Collaborate cross-functionally to ensure alignment and measure performan...
Reposted 5 days ago
$110K - $130K *
Empower our revenue team by building and scaling GTM systems. Collaborate with sales, finance, and engineering to enhance Salesforce and optimize workflows, ensuring accurate forecasting and seamless...
3 days ago
Marketing Manager - Operations
$88K - $105K *
Transform your career by leading strategic marketing initiatives that enhance brand visibility and drive revenue growth. Collaborate with cross-functional teams to create compelling content and optimi...
1 week ago
$90K - $152K *
Advance your career by leading mainframe capacity planning initiatives, optimizing performance, and driving automation solutions. Collaborate with teams to enhance operational efficiency and mentor ju...
1 week ago
$90K - $189K *
Elevate your career as a Database Administrator, ensuring robust Oracle database support, leveraging AWS, and troubleshooting complex system issues across diverse platforms in a collaborative, client...
Reposted 2 weeks ago
$120K - $190K *
Unlock potential by leading the design and integration of advanced satellite communications systems. Drive system architecture, manage requirements, and collaborate across multi-disciplinary teams to...
5 days ago
$100K - $120K *
Drive innovation in digital experiences by building and optimizing high-performing web applications. Collaborate with creative teams to enhance customer engagement across platforms while managing the...
3 weeks ago
Staff Backend Engineer - Infrastructure Access - US
$135K - $160K *
Transform the Teleport Core Product by tackling performance, scalability, and security challenges. Lead a distributed team to design, develop, and implement high-quality solutions while enhancing obse...
1 week ago
$275K - $325K *
Join a team that's redefining financing products through innovative engineering. Lead complex initiatives, modernize systems, and leverage AI tools to enhance software development while ensuring data...
4 days ago
$88K - $105K *
Join a dynamic team to oversee the implementation of technology programs, ensuring alignment with client needs and regulatory requirements. Collaborate with cross-functional teams to manage documentat...
2 weeks ago
Senior Platform Engineer (FedD202)
$148K - $201K *
Empower application teams by integrating, securing, and deploying software in Kubernetes environments. Collaborate across platforms to enhance CI/CD processes and ensure reliable operations, driving i...
3 weeks ago
$90K - $136K *
Join a team that's redefining customer experience by translating complex business needs into actionable technical requirements, ensuring seamless integration across platforms and delivering innovative...
1 week ago
$75K - $96K *
Optimize AI triage and automation processes while engineering secure data pipelines. Collaborate with teams to enhance security alert resolution and streamline workflows, ensuring effective integratio...
6 days ago
$75K - $96K *
Unlock your potential as a key player in our overnight security operations, enhancing AI-driven incident response and automation. Your expertise will shape how we detect and respond to threats, ensuri...
1 week ago
$80K - $95K *
Innovate with us as a Process Engineer, optimizing workflows and enhancing operational efficiency for new data center projects. Collaborate across teams to implement solutions that drive productivity...
2 weeks ago
Staff/Principal Design Systems Lead
$150K - $180K *
Drive the evolution of our design system by building foundational infrastructure that empowers designers, engineers, and AI agents to create cohesive, high-quality experiences while leading a growing...
1 week ago
Senior Systems Engineer (R&D Innovation)
$107K - $161K *
Innovate in R&D as a Senior Systems Engineer, bridging early-stage tech and production. Drive feasibility studies, prototype emerging features, and collaborate with partners to advance next-gen archit...
4 days ago
What types of high-paying jobs can I find in Missouri?
Missouri listings may include professional roles in technology, healthcare, finance, engineering, manufacturing, logistics, operations, and executive leadership. Available positions depend on current employer hiring needs.
Do Missouri jobs on Ladders pay at least $100,000?
Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review the individual listing for its compensation information and requirements.
Where in Missouri can I search for jobs?
Explore opportunities in cities such as Kansas City, St. Louis, Springfield, and Columbia, as well as other locations across Missouri. Availability varies by role and employer.
How can I find a Missouri job that fits my experience?
Browse current listings and compare responsibilities, qualifications, location, and compensation with your experience and career goals. Apply to positions that align with your background.