Find your next career opportunity with Missouri jobs paying $100,000 or more on Ladders. Browse vetted professional roles across the state, from major employers in Kansas City and St. Louis to growing organizations in Springfield, Columbia, and other communities. Listings may include opportunities in technology, healthcare, finance, engineering, operations, and executive leadership.
Missouri’s diverse economy supports professional careers across industries such as financial services, healthcare, manufacturing, logistics, technology, and agriculture. Whether you’re looking for an established corporate role or a position with a growing organization, explore openings that match your experience, skills, and compensation goals.
Use Ladders to discover vetted jobs with salaries of at least $100,000. Review each listing for details about responsibilities, qualifications, location, and compensation, then focus your search on opportunities that align with your career plans. Job availability and salary details vary by employer and role.
From metropolitan career hubs to communities throughout Missouri, high-paying roles can offer different work environments and paths for advancement. Explore current listings and find professional opportunities that fit the way you want to work and grow.
$112K - $126K *
Elevate AI capabilities by building and maintaining governed solutions. Collaborate cross-functionally to translate business needs into technical designs, ensuring ethical AI use and robust integratio...
1 week ago
Senior Preconstruction Manager
$110K - $130K *
Champion preconstruction initiatives for large-scale commercial projects, ensuring accurate estimates, client satisfaction, and alignment with company goals through effective communication and relatio...
Reposted 2 weeks ago
Senior Preconstruction Manager
$100K - $120K *
Shape the future of commercial construction by driving preconstruction excellence, managing budgets, schedules, and subcontractor relationships while ensuring client satisfaction and project alignment...
Reposted 2 weeks ago
$156K - $260K *
Empower cyber defense initiatives by designing, implementing, and optimizing advanced security solutions. Lead investigations, mentor teams, and enhance detection capabilities to proactively mitigate...
3 weeks ago
Senior Software Engineer, AV Analysis Platform
$224K - $356K *
Pioneer the development of advanced evaluation tools for Autonomous Vehicles, enhancing workflows and system performance. Collaborate with cross-functional teams to deliver scalable solutions that imp...
1 week ago
Growth Executive - North America
$120K - $160K *
Elevate business growth by driving strategic sales initiatives across key sectors. Leverage your network to build relationships and develop tailored solutions, while collaborating with partners to enh...
4 weeks ago
Senior Principal AI Solutions Architect
$149K - $223K *
Unlock potential by leading enterprise AI solutions, bridging sales and technical teams to deliver impactful transformations. Engage with customers to architect scalable solutions, ensuring operationa...
Reposted 3 days ago
$110K - $130K *
Champion the maintenance and optimization of Oracle databases in AWS, ensuring system integrity and performance. Collaborate with teams to implement solutions, manage configurations, and support compl...
4 weeks ago
$82K - $172K *
Innovate your career as you design and maintain mission-critical software for defense financial systems. Lead a growing team, integrate AI capabilities, and ensure compliance in both classified and un...
1 week ago
Senior Program Manager/Engineering Manager
$125K - $225K *
Lead the charge in multidisciplinary engineering and design management for a large-scale industrial infrastructure project, ensuring compliance with technical standards and client expectations through...
1 week ago
$158K - $237K *
Accelerate progress at the forefront of aerospace innovation by leading the B-2 program and Air Combat Systems portfolio, managing all phases from inception to completion while fostering customer rela...
1 week ago
$158K - $237K *
Lead major aircraft repair efforts as a Program Manager, overseeing all phases from inception to completion. Manage resources, cultivate customer relationships, and ensure compliance while driving pro...
1 week ago
Director of Strategy - Innovations
$125K - $150K *
Lead the execution of strategic initiatives across functions, ensuring alignment and standardization. Collaborate with leadership to drive performance visibility and enhance communication, fostering a...
4 days ago
$110K - $130K *
Empower your career by leading IT security initiatives, assessing risks, and driving remediation efforts across the enterprise. Collaborate with cross-functional teams to enhance security posture and...
Reposted 2 weeks ago
Technical Sales Lead - USA GOV
$144K - $230K *
Engage with our sales team as a Technical Sales Lead, driving technology evaluations and managing customer relationships. Leverage your expertise in telecommunications to ensure satisfaction throughou...
1 week ago
Deputy Director, Partnerships & Technical Integration
$196K - $210K *
Partner with us to shape the future of semiconductor workforce development by aligning industry needs with educational strategies, fostering partnerships, and leading initiatives that ensure technical...
Reposted 6 days ago
Director, Strategic Partner Accounts - Optiv/Guidepoint
$159K - $243K *
Collaborate with strategic partners to drive business growth, enhance sales capabilities, and execute comprehensive business plans. Leverage existing relationships to maximize partner engagement and a...
3 weeks ago
Professional Services Consultant
$95K - $115K *
Engage with clients to transform complex Enterprise Architecture needs into actionable solutions. Manage implementation workstreams, ensuring effective onboarding and training while fostering strong r...
3 weeks ago
Cyber Security Engineer - NSS Tools
$75K - $158K *
Join our dynamic team to design and deploy cybersecurity solutions across multiple global networks, ensuring the protection of critical information and infrastructure in support of national security m...
Reposted 2 weeks ago
Senior Lead Electrical Engineer, Datacenter
$160K - $230K *
Deliver advanced electrical engineering solutions for hyperscale data centers. Lead design teams, oversee project execution, and ensure compliance with industry standards while fostering client relati...
Yesterday
Sr. Capture Manager (Enterprise Pursuits)
$120K - $145K *
Champion strategic growth by leading major enterprise pursuits, fostering collaboration, and driving consultative sales processes. Leverage your expertise to develop winning strategies and ensure oper...
5 days ago
Director, Professional Services & Consulting
$199K - $285K *
Lead a high-performing team to drive professional services excellence in public sector deployments, ensuring alignment with Zero Trust mandates and delivering impactful solutions for federal, state, a...
6 days ago
$99K - $232K *
Unlock potential by leading innovative solution architecture efforts, guiding teams in cloud engineering, data analytics, and digital integration. Drive technical direction and mentor junior professio...
3 weeks ago
$99K - $232K *
Transform solution architecture by leading innovative software design efforts, connecting business needs with cloud engineering and analytics. Guide teams, mentor junior professionals, and ensure deli...
3 weeks ago
$138K - $193K *
Unlock potential by designing and optimizing private cloud infrastructure, serving as a technical expert in software-defined data center solutions, and collaborating with teams to ensure successful pr...
Yesterday
What types of high-paying jobs can I find in Missouri?
Missouri listings may include professional roles in technology, healthcare, finance, engineering, manufacturing, logistics, operations, and executive leadership. Available positions depend on current employer hiring needs.
Do Missouri jobs on Ladders pay at least $100,000?
Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review the individual listing for its compensation information and requirements.
Where in Missouri can I search for jobs?
Explore opportunities in cities such as Kansas City, St. Louis, Springfield, and Columbia, as well as other locations across Missouri. Availability varies by role and employer.
How can I find a Missouri job that fits my experience?
Browse current listings and compare responsibilities, qualifications, location, and compensation with your experience and career goals. Apply to positions that align with your background.