Find your next career opportunity with Missouri jobs paying $100,000 or more on Ladders. Browse vetted professional roles across the state, from major employers in Kansas City and St. Louis to growing organizations in Springfield, Columbia, and other communities. Listings may include opportunities in technology, healthcare, finance, engineering, operations, and executive leadership.
Missouri’s diverse economy supports professional careers across industries such as financial services, healthcare, manufacturing, logistics, technology, and agriculture. Whether you’re looking for an established corporate role or a position with a growing organization, explore openings that match your experience, skills, and compensation goals.
Use Ladders to discover vetted jobs with salaries of at least $100,000. Review each listing for details about responsibilities, qualifications, location, and compensation, then focus your search on opportunities that align with your career plans. Job availability and salary details vary by employer and role.
From metropolitan career hubs to communities throughout Missouri, high-paying roles can offer different work environments and paths for advancement. Explore current listings and find professional opportunities that fit the way you want to work and grow.
$120K - $145K *
Drive the design and optimization of Oracle CX data architecture, ensuring effective data conversion and integration. Collaborate with cross-functional teams to enhance customer experience through inn...
1 week ago
$133K - $262K *
Unlock potential by developing AI-driven solutions that enhance business processes and integrate with enterprise systems. Collaborate with clients and teams to shape the future of finance and accounti...
Today
Salesforce Senior/ Director Technical Architect, FINS/LSC
$148K - $313K *
Unlock potential by serving as a strategic advisor to enterprise clients, guiding them in architecting AI-first solutions within the Life Sciences sector, while driving internal initiatives and enhanc...
Reposted 1 week ago
Associate Technical Architect - Data - USA
$125K - $150K *
Champion innovative data solutions by architecting scalable cloud data pipelines and lakes. Leverage deep financial services expertise to drive technical product management and ensure seamless data in...
Today
$130K - $145K *
Lead the development and enhancement of modern web applications using Java, Spring, and Angular. Collaborate with cross-functional teams in an Agile environment to deliver reliable solutions while men...
3 weeks ago
$130K - $160K *
Transform enterprise solutions as a Salesforce Solution Architect, leading teams to deliver innovative, scalable projects. Drive presales, guide architecture, and leverage cutting-edge AI capabilities...
3 weeks ago
$150K - $170K *
Lead strategic contracts management, overseeing development and negotiation of federal contracts. Collaborate cross-functionally to ensure compliance and risk management while driving organizational g...
Yesterday
$95K - $115K *
Lead the charge in developing custom Duck Creek solutions, collaborating with clients and teams to deliver scalable, technical solutions while mentoring junior developers and driving project success...
2 weeks ago
Senior Engineer - Mechanical Design
$95K - $115K *
Elevate your career by leading mechanical design for mission-critical facilities. Collaborate with teams, mentor junior engineers, and ensure project success through innovative solutions and precise e...
1 week ago
Senior Product Designer, Mobile
$110K - $130K *
Unlock potential by designing intuitive AI experiences for diverse construction teams, blending interaction and visual design. You'll create mobile-first solutions for Superintendents and DCOs, ensuri...
Reposted yesterday
$120K - $170K *
Shape the future of enterprise infrastructure by leading design, implementation, and optimization of systems. Drive automation, enhance security, and mentor junior staff while collaborating on strateg...
1 week ago
Program Director- Mainframe Optimization & Delivery
$135K - $205K *
Lead strategic client engagements to optimize mainframe environments, enhance operational efficiency, and deliver transformational programs. Collaborate with cross-functional teams to ensure successfu...
4 days ago
Sr. Process Engineer - Semi Conductor
$88K - $154K *
Advance your career by leading process engineering for semiconductor projects. Collaborate with cross-functional teams to optimize systems, ensuring compliance with industry standards while mentoring...
Today
$80K - $121K *
Join us to drive sales growth by identifying new business opportunities and nurturing client relationships. Leverage your technical and business acumen to influence stakeholders and close deals while...
3 weeks ago
$100K - $120K *
Help us drive growth by identifying and closing automation opportunities. Collaborate with technical teams to deliver tailored solutions, build lasting customer relationships, and exceed sales targets...
2 weeks ago
Federal Enterprise Solution Architect
$128K - $160K *
Empower federal agencies by delivering tailored data governance solutions, ensuring compliance and driving measurable outcomes. Collaborate cross-functionally to enhance customer success and expand Co...
Reposted today
$82K - $172K *
Advance your career as an Embedded Linux Software Developer, contributing to the evolution of mission-critical devices. Collaborate with cross-functional teams to enhance networking capabilities and d...
Reposted 2 weeks ago
Senior Windows Engineer - Managed Services
$106K - $150K *
Unlock potential by providing expert operational support for Windows environments. Manage complex incidents, ensure service availability, and collaborate across teams to enhance customer experiences i...
3 weeks ago
$112K - $135K *
Elevate your career by designing and implementing cloud infrastructure solutions in Azure. Collaborate with teams to automate deployments, optimize CI/CD pipelines, and leverage AI tools for enhanced...
4 days ago
Consulting Solution Architect - Digital Experience
$117K - $170K *
Lead the charge in developing innovative Digital Experience solutions, collaborating with customers and internal teams to drive growth. Provide expert guidance in unified communications and build stra...
1 week ago
AI Infrastructure Engineer [Senior]
$150K - $180K *
Transform AI infrastructure by designing and maintaining production-grade systems across multiple cloud providers. Engage in hands-on architecture decisions, ensuring reliability, security, and automa...
5 days ago
Remote Construction Program Manager
$133K - $200K *
Champion the delivery of advanced manufacturing capabilities by leading cross-functional teams, managing project lifecycles, and ensuring alignment with customer and stakeholder expectations for succe...
Today
Senior Attack Engineer, External
$206K - $242K *
Transform external attack capabilities by developing scalable workflows and automating reconnaissance processes. Drive innovation in offensive security, mentor teammates, and contribute to a high-impa...
2 weeks ago
Senior Product Builder, Partner Integrations
$122K - $180K *
Accelerate product development by defining, designing, and prototyping features for partner integrations, leveraging AI tools and user feedback to enhance payment processing solutions and maintain com...
1 week ago
Senior Security Engineer, Information Technology
$110K - $130K *
Drive security excellence as a Senior Security Engineer, enhancing IAM, PAM, cloud security, and AI governance. Collaborate with teams to implement robust security measures, automate processes, and le...
3 weeks ago
What types of high-paying jobs can I find in Missouri?
Missouri listings may include professional roles in technology, healthcare, finance, engineering, manufacturing, logistics, operations, and executive leadership. Available positions depend on current employer hiring needs.
Do Missouri jobs on Ladders pay at least $100,000?
Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review the individual listing for its compensation information and requirements.
Where in Missouri can I search for jobs?
Explore opportunities in cities such as Kansas City, St. Louis, Springfield, and Columbia, as well as other locations across Missouri. Availability varies by role and employer.
How can I find a Missouri job that fits my experience?
Browse current listings and compare responsibilities, qualifications, location, and compensation with your experience and career goals. Apply to positions that align with your background.