Find your next career opportunity with Missouri jobs paying $100,000 or more on Ladders. Browse vetted professional roles across the state, from major employers in Kansas City and St. Louis to growing organizations in Springfield, Columbia, and other communities. Listings may include opportunities in technology, healthcare, finance, engineering, operations, and executive leadership.
Missouri’s diverse economy supports professional careers across industries such as financial services, healthcare, manufacturing, logistics, technology, and agriculture. Whether you’re looking for an established corporate role or a position with a growing organization, explore openings that match your experience, skills, and compensation goals.
Use Ladders to discover vetted jobs with salaries of at least $100,000. Review each listing for details about responsibilities, qualifications, location, and compensation, then focus your search on opportunities that align with your career plans. Job availability and salary details vary by employer and role.
From metropolitan career hubs to communities throughout Missouri, high-paying roles can offer different work environments and paths for advancement. Explore current listings and find professional opportunities that fit the way you want to work and grow.
$110K - $135K *
Unlock excellence in PCB design and manufacturing by leading DFM initiatives, developing complex multilayer layouts, and shaping best practices across engineering teams to enhance product performance...
2 weeks ago
Senior Director, Dedicated Infrastructure & Platforms
$279K - $349K *
Drive the strategy and execution of dedicated infrastructure engineering, leading a high-performing team to enhance enterprise SaaS offerings, ensure compliance, and deliver exceptional customer exper...
1 week ago
$110K - $130K *
Join a dynamic team as a SOC Engineer, where you'll onboard customers into managed security services, configure Microsoft security tools, and ensure reliable telemetry across diverse environments, all...
3 weeks ago
Sr. Manager, Solutions Architect - SMB
$135K - $160K *
Transform customer engagement by leading a team of Solutions Architects, driving technical strategy and operational excellence across the India region while ensuring alignment with cross-functional pa...
1 week ago
$115K - $117K *
Join a team that's dedicated to enhancing privacy compliance and cybersecurity. Collaborate with stakeholders to assess risks, develop training, and ensure adherence to federal regulations while prote...
3 weeks ago
Senior Consultant I - Network Security Engineering
$75K - $126K *
Innovate with us to enhance network security platforms, ensuring robust protection and operational efficiency. As a key engineer, you'll tackle complex challenges, automate processes, and collaborate...
2 weeks ago
Senior Manager, Adversary Research
$104K - $259K *
Engage in cutting-edge adversary research to lead a team in identifying and analyzing sophisticated cyber threats. Drive strategic initiatives, enhance security outcomes, and communicate findings to d...
1 week ago
Staff Software Engineer, Tech Lead - NetBox Delivery
$135K - $160K *
Unlock the potential of NetBox Delivery by leading software design, enhancing production reliability, and mentoring engineers. Shape the technical direction and ensure seamless deployment on Cloud and...
3 weeks ago
$165K - $195K *
Engage in strategic solution development for Federal Government initiatives, translating client needs into innovative technical strategies. Collaborate with cross-functional teams to deliver compellin...
1 week ago
$150K - $170K *
Elevate employee experiences by leading the design and implementation of integrated HR Service Delivery solutions leveraging ServiceNow and Microsoft technologies...
Reposted 3 days ago
Radar Signal Processing Engineer
$95K - $115K *
Transform the future of radar technology by developing advanced signal processing algorithms within a collaborative R&D environment, enhancing radar systems through innovative research and multidiscip...
Reposted 3 weeks ago
Experienced Civil Engineer - Data Center
$77K - $102K *
Lead the charge in delivering innovative civil engineering solutions for large-scale data center projects. Collaborate with multidisciplinary teams while developing your skills and expertise in a supp...
Reposted 1 week ago
Senior Electrical Design Engineer
$135K - $180K *
Drive innovative electrical design solutions for high-density compute environments. Collaborate across teams to ensure compliance with industry standards while mentoring junior engineers. Make a signi...
1 week ago
$90K - $113K *
Take ownership of contract administration for government and commercial agreements. Collaborate cross-functionally to ensure compliance, manage risks, and drive process improvements while supporting t...
Yesterday
Engagement Manager, Managed Services (Networking)
$175K - $225K *
Drive successful customer engagements by managing technical sales processes, designing enterprise-level solutions, and building strong relationships to close deals. Leverage your expertise to enhance...
Reposted 4 weeks ago
$82K - $131K *
Elevate customer engagement by driving successful project delivery, fostering collaboration across teams, and ensuring satisfaction through proactive communication and effective management of complex...
Reposted 3 weeks ago
$125K - $150K *
Drive your career with innovative AI-driven automation solutions that enhance IT operations and user experience. Collaborate across teams to minimize manual tasks, improve efficiency, and implement in...
1 week ago
$96K - $130K *
Join a dynamic team to shape innovative fundraising tools that empower progressive campaigns and nonprofits. Leverage modern technologies to enhance election readiness and compliance, while mentoring...
Reposted 1 week ago
$150K - $200K *
Drive strategic partnerships and optimize alliances to enhance revenue growth. Lead co-sell initiatives and ensure seamless partner engagement, leveraging data insights to maximize impact in AI and cl...
3 weeks ago
$110K - $130K *
Shape the future of enterprise data strategy and architecture, ensuring governance, quality, and integration across the organization. Lead modernization efforts and establish standards for data manage...
4 days ago
$110K - $130K *
Empower your career as a Platform Engineer, driving innovation in system architecture and cloud technologies. Collaborate with cross-functional teams to enhance platform efficiency and guide junior en...
3 weeks ago
Staff Security Analyst (Governance and Trust)
$151K - $178K *
Shape the future of compliance and trust in software security. Lead external examinations, manage customer diligence, and oversee third-party risk operations while mentoring a growing team dedicated t...
6 days ago
Solution Architect ServiceNow Service Portal and AI Engineering
$125K - $150K *
Transform customer experiences by architecting and delivering innovative Service Portal and AI solutions. Lead technical design and implementation, ensuring reliable software that meets business needs...
4 weeks ago
$80K - $95K *
Optimize data management processes for large government acquisitions, ensuring effective communication between teams and shipyards. Lead document management, maintain schedules, and enhance data quali...
5 days ago
Global Expansion Project Manager - FedRAMP
$100K - $130K *
Champion global expansion initiatives by managing the FedRAMP program. Collaborate with cross-functional teams to ensure project timelines and deliverables are met while navigating a fast-paced enviro...
3 weeks ago
What types of high-paying jobs can I find in Missouri?
Missouri listings may include professional roles in technology, healthcare, finance, engineering, manufacturing, logistics, operations, and executive leadership. Available positions depend on current employer hiring needs.
Do Missouri jobs on Ladders pay at least $100,000?
Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review the individual listing for its compensation information and requirements.
Where in Missouri can I search for jobs?
Explore opportunities in cities such as Kansas City, St. Louis, Springfield, and Columbia, as well as other locations across Missouri. Availability varies by role and employer.
How can I find a Missouri job that fits my experience?
Browse current listings and compare responsibilities, qualifications, location, and compensation with your experience and career goals. Apply to positions that align with your background.