Explore High-Paying Jobs in Missouri

Find your next career opportunity with Missouri jobs paying $100,000 or more on Ladders. Browse vetted professional roles across the state, from major employers in Kansas City and St. Louis to growing organizations in Springfield, Columbia, and other communities. Listings may include opportunities in technology, healthcare, finance, engineering, operations, and executive leadership.

Career Opportunities Across Missouri

Missouri’s diverse economy supports professional careers across industries such as financial services, healthcare, manufacturing, logistics, technology, and agriculture. Whether you’re looking for an established corporate role or a position with a growing organization, explore openings that match your experience, skills, and compensation goals.

Find Roles That Match Your Goals

Use Ladders to discover vetted jobs with salaries of at least $100,000. Review each listing for details about responsibilities, qualifications, location, and compensation, then focus your search on opportunities that align with your career plans. Job availability and salary details vary by employer and role.

Build Your Career in the Show-Me State

From metropolitan career hubs to communities throughout Missouri, high-paying roles can offer different work environments and paths for advancement. Explore current listings and find professional opportunities that fit the way you want to work and grow.

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1,000+

Network Architect Jobs in Missouri

Sort By: Relevance

$110K - $135K *

Unlock excellence in PCB design and manufacturing by leading DFM initiatives, developing complex multilayer layouts, and shaping best practices across engineering teams to enhance product performance...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Manufacturing & Automotive

$279K - $349K *

Drive the strategy and execution of dedicated infrastructure engineering, leading a high-performing team to enhance enterprise SaaS offerings, ensure compliance, and deliver exceptional customer exper...

RemoteRemote

1 week ago

  •   Less than 5 years exp.  •   Information Technology

$110K - $130K *

Join a dynamic team as a SOC Engineer, where you'll onboard customers into managed security services, configure Microsoft security tools, and ensure reliable telemetry across diverse environments, all...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$135K - $160K *

Transform customer engagement by leading a team of Solutions Architects, driving technical strategy and operational excellence across the India region while ensuring alignment with cross-functional pa...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Information Technology

$115K - $117K *

Join a team that's dedicated to enhancing privacy compliance and cybersecurity. Collaborate with stakeholders to assess risks, develop training, and ensure adherence to federal regulations while prote...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Business Services

$75K - $126K *

Innovate with us to enhance network security platforms, ensuring robust protection and operational efficiency. As a key engineer, you'll tackle complex challenges, automate processes, and collaborate...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Finance & Insurance

$104K - $259K *

Engage in cutting-edge adversary research to lead a team in identifying and analyzing sophisticated cyber threats. Drive strategic initiatives, enhance security outcomes, and communicate findings to d...

United StatesRemote

1 week ago

  •   11 - 15 years exp.  •   Information Technology

$135K - $160K *

Unlock the potential of NetBox Delivery by leading software design, enhancing production reliability, and mentoring engineers. Shape the technical direction and ensure seamless deployment on Cloud and...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$165K - $195K *

Engage in strategic solution development for Federal Government initiatives, translating client needs into innovative technical strategies. Collaborate with cross-functional teams to deliver compellin...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Healthcare

$150K - $170K *

Elevate employee experiences by leading the design and implementation of integrated HR Service Delivery solutions leveraging ServiceNow and Microsoft technologies...

RemoteRemote

Reposted 3 days ago

  •   5 - 7 years exp.  •   Information Technology

$95K - $115K *

Transform the future of radar technology by developing advanced signal processing algorithms within a collaborative R&D environment, enhancing radar systems through innovative research and multidiscip...

Reposted 3 weeks ago

  •   Less than 5 years exp.  •   Aerospace & Defense

$77K - $102K *

Lead the charge in delivering innovative civil engineering solutions for large-scale data center projects. Collaborate with multidisciplinary teams while developing your skills and expertise in a supp...

Reposted 1 week ago

  •   Less than 5 years exp.  •   Finance & Insurance

$135K - $180K *

Drive innovative electrical design solutions for high-density compute environments. Collaborate across teams to ensure compliance with industry standards while mentoring junior engineers. Make a signi...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Information Technology

$90K - $113K *

Take ownership of contract administration for government and commercial agreements. Collaborate cross-functionally to ensure compliance, manage risks, and drive process improvements while supporting t...

United StatesRemote

Yesterday

  •   5 - 7 years exp.  •   Information Technology

$175K - $225K *

Drive successful customer engagements by managing technical sales processes, designing enterprise-level solutions, and building strong relationships to close deals. Leverage your expertise to enhance...

United StatesRemote

Reposted 4 weeks ago

  •   8 - 10 years exp.  •   Information Technology

$82K - $131K *

Elevate customer engagement by driving successful project delivery, fostering collaboration across teams, and ensuring satisfaction through proactive communication and effective management of complex...

RemoteRemote

Reposted 3 weeks ago

  •   8 - 10 years exp.  •   Telecommunications & Hardware

$125K - $150K *

Drive your career with innovative AI-driven automation solutions that enhance IT operations and user experience. Collaborate across teams to minimize manual tasks, improve efficiency, and implement in...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Manufacturing & Automotive

$96K - $130K *

Join a dynamic team to shape innovative fundraising tools that empower progressive campaigns and nonprofits. Leverage modern technologies to enhance election readiness and compliance, while mentoring...

United StatesRemote

Reposted 1 week ago

  •   5 - 7 years exp.  •   Enterprise Technology

$150K - $200K *

Drive strategic partnerships and optimize alliances to enhance revenue growth. Lead co-sell initiatives and ensure seamless partner engagement, leveraging data insights to maximize impact in AI and cl...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$110K - $130K *

Shape the future of enterprise data strategy and architecture, ensuring governance, quality, and integration across the organization. Lead modernization efforts and establish standards for data manage...

4 days ago

  •   8 - 10 years exp.  •   Finance & Insurance

$110K - $130K *

Empower your career as a Platform Engineer, driving innovation in system architecture and cloud technologies. Collaborate with cross-functional teams to enhance platform efficiency and guide junior en...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Information Technology

$151K - $178K *

Shape the future of compliance and trust in software security. Lead external examinations, manage customer diligence, and oversee third-party risk operations while mentoring a growing team dedicated t...

United StatesRemote

6 days ago

  •   Less than 5 years exp.  •   Information Technology

$125K - $150K *

Transform customer experiences by architecting and delivering innovative Service Portal and AI solutions. Lead technical design and implementation, ensuring reliable software that meets business needs...

United StatesRemote

4 weeks ago

  •   5 - 7 years exp.  •   Enterprise Technology

$80K - $95K *

Optimize data management processes for large government acquisitions, ensuring effective communication between teams and shipyards. Lead document management, maintain schedules, and enhance data quali...

United StatesRemote

5 days ago

  •   8 - 10 years exp.  •   Information Technology

$100K - $130K *

Champion global expansion initiatives by managing the FedRAMP program. Collaborate with cross-functional teams to ensure project timelines and deliverables are met while navigating a fast-paced enviro...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Information Technology

Frequently Asked Questions (FAQ)

  • What types of high-paying jobs can I find in Missouri?question toggle

    Missouri listings may include professional roles in technology, healthcare, finance, engineering, manufacturing, logistics, operations, and executive leadership. Available positions depend on current employer hiring needs.

  • Do Missouri jobs on Ladders pay at least $100,000?question toggle

    Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review the individual listing for its compensation information and requirements.

  • Where in Missouri can I search for jobs?question toggle

    Explore opportunities in cities such as Kansas City, St. Louis, Springfield, and Columbia, as well as other locations across Missouri. Availability varies by role and employer.

  • How can I find a Missouri job that fits my experience?question toggle

    Browse current listings and compare responsibilities, qualifications, location, and compensation with your experience and career goals. Apply to positions that align with your background.