Find your next career opportunity with Missouri jobs paying $100,000 or more on Ladders. Browse vetted professional roles across the state, from major employers in Kansas City and St. Louis to growing organizations in Springfield, Columbia, and other communities. Listings may include opportunities in technology, healthcare, finance, engineering, operations, and executive leadership.
Missouri’s diverse economy supports professional careers across industries such as financial services, healthcare, manufacturing, logistics, technology, and agriculture. Whether you’re looking for an established corporate role or a position with a growing organization, explore openings that match your experience, skills, and compensation goals.
Use Ladders to discover vetted jobs with salaries of at least $100,000. Review each listing for details about responsibilities, qualifications, location, and compensation, then focus your search on opportunities that align with your career plans. Job availability and salary details vary by employer and role.
From metropolitan career hubs to communities throughout Missouri, high-paying roles can offer different work environments and paths for advancement. Explore current listings and find professional opportunities that fit the way you want to work and grow.
Cloud Platform Engineer (PaaS)
$155K - $165K *
Explore innovative solutions as a Hybrid Cloud Platform Engineer, collaborating with Agile teams to enhance a mission-critical PaaS for the Intelligence Community, ensuring secure deployment of applic...
4 weeks ago
$120K - $145K *
Partner with us to drive customer success by implementing and expanding Teleport solutions. Leverage your expertise to enhance adoption, troubleshoot issues, and deliver tailored training, ensuring cl...
1 week ago
SAP Business AI Lead Architect
$160K - $229K *
Lead the design and development of AI-driven solutions within SAP S/4HANA, integrating advanced AI technologies to drive business transformation and innovation across enterprise environments. Mentor t...
1 week ago
Cloud Concierge Technical Analyst
$80K - $95K *
Drive cloud onboarding success by guiding application owners through migration complexities, ensuring effective communication and collaboration across teams to enhance operational efficiency and suppo...
5 days ago
Manager of Security and Compliance
$130K - $150K *
Elevate your career by leading security and compliance initiatives in a dynamic healthcare SaaS environment. Drive key programs, manage audits, and partner with cross-functional teams to ensure regula...
4 weeks ago
$115K - $130K *
Lead the Archibus platform for a major Life Sciences client, driving enhancements and integrations while ensuring data integrity and user satisfaction. Collaborate with cross-functional teams to optim...
1 week ago
$105K - $150K *
Transform your career by joining a dynamic team focused on enhancing security compliance for cloud services. Leverage your expertise in IT security to assess architectures, guide vendors, and ensure a...
5 days ago
$160K - $229K *
Transform client experiences by leading SAP CX solutions, ensuring seamless integration and delivery from discovery to go-live while collaborating with cross-functional teams to drive business success...
1 week ago
$90K - $110K *
Manage day-to-day infrastructure and customer support, ensuring optimal server performance, security, and incident response. Collaborate on initiatives to enhance operational security and maintain doc...
3 weeks ago
Manager, Design Engineering - Optical
$84K - $130K *
Lead a dynamic team of Optical Design Engineers to innovate and implement cutting-edge DWDM network solutions, ensuring project success and exceeding performance targets while collaborating across dep...
3 weeks ago
Lead Platform Engineer/Architect - HPC, Kubernetes
$150K - $180K *
Accelerate progress at a high-growth infrastructure team managing Kubernetes platforms across multiple clouds. You'll enhance GPU resource efficiency and ensure system reliability while collaborating...
3 weeks ago
$120K - $140K *
Analyze and enhance the digital customer journey by leading automation initiatives and cross-functional programs. Collaborate with teams to identify friction points and implement solutions that improv...
5 days ago
Principal Consultant - Financial Services Cloud Architect
$135K - $160K *
Unlock potential by leading transformative Salesforce solutions in financial services. As a trusted advisor, you'll architect scalable solutions, align technology with business goals, and drive best p...
3 weeks ago
$90K - $113K *
Transform data management processes by bridging business needs with technical execution. Support data pipeline maintenance, ensure data quality, and assist in BI reporting to enhance operational effic...
3 weeks ago
Technical Consultant - ArcGIS Enterprise Systems | TS/SCI
$84K - $142K *
Empower mission-driven customers by designing and optimizing ArcGIS Enterprise environments. Leverage hands-on expertise and enterprise IT knowledge to navigate complex technology landscapes and deliv...
Reposted today
Software Engineer, Infrastructure
$135K - $160K *
Drive the development and deployment of a cutting-edge control plane for identity and credential management, ensuring reliability and security in customer-hosted environments while collaborating with...
1 week ago
$115K - $149K *
Innovate financial processes by leading NetSuite design and implementation. Collaborate with finance and technical teams to optimize solutions for accounting, planning, and reporting, ensuring data in...
5 days ago
Healthcare Integration Architect
$52K - $132K *
Champion the future of healthcare integration by resolving complex technical issues, analyzing architectures, and collaborating with teams to enhance interoperability in mission-critical environments...
Today
Consulting Systems Engineer - Global Service Provider
$100K - $150K *
Drive technical pre-sales efforts by collaborating with sales teams to design innovative solutions for service provider clients, leveraging expertise in IT, cloud, and networking technologies to addre...
6 days ago
$150K - $250K *
Drive end-to-end client success for strategic accounts by optimizing AI deployment and fostering relationships. Engage with diverse stakeholders while building scalable systems for enhanced client exp...
Reposted 3 days ago
$110K - $125K *
Shape the future of integration projects by owning technical direction, ensuring seamless execution, and fostering client trust. Collaborate with sales and development teams to deliver clear documenta...
2 weeks ago
$135K - $220K *
Lead the charge in enhancing security tooling for compliance and cybersecurity. Collaborate with engineering teams to automate security checks, ensuring a robust pipeline that balances speed and secur...
1 week ago
Staff Product Manager, Network Observability
$135K - $160K *
Lead the charge in shaping innovative Network Observability products, driving strategy from concept to launch. Collaborate with cross-functional teams to deliver solutions that empower operators to op...
2 weeks ago
$221K - $332K *
Lead the charge in transforming service providers through Calix Cloud solutions. Collaborate with teams to design cloud architectures, deliver demos, and guide customers in complex decision-making, dr...
Yesterday
$150K - $180K *
Develop and implement MLOps strategy for enterprise-grade ML systems, driving model lifecycle management. Collaborate with teams to design scalable pipelines and ensure high reliability across ML solu...
Reposted 1 week ago
What types of high-paying jobs can I find in Missouri?
Missouri listings may include professional roles in technology, healthcare, finance, engineering, manufacturing, logistics, operations, and executive leadership. Available positions depend on current employer hiring needs.
Do Missouri jobs on Ladders pay at least $100,000?
Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review the individual listing for its compensation information and requirements.
Where in Missouri can I search for jobs?
Explore opportunities in cities such as Kansas City, St. Louis, Springfield, and Columbia, as well as other locations across Missouri. Availability varies by role and employer.
How can I find a Missouri job that fits my experience?
Browse current listings and compare responsibilities, qualifications, location, and compensation with your experience and career goals. Apply to positions that align with your background.