Explore $100K+ Jobs in Mississippi

Discover professional opportunities in Mississippi with salaries of $100,000 or more. Ladders features vetted roles for experienced candidates seeking senior-level careers across the Magnolia State, from Jackson and the Gulf Coast to regional business hubs.

Mississippi Careers Across Industries

High-paying opportunities may be available in healthcare, technology, manufacturing, finance, energy, engineering, and executive leadership. Job availability and requirements vary by employer, location, and experience level, so review each listing for details.

Find Opportunities by Location

Search roles in Jackson, Gulfport, Biloxi, Hattiesburg, Southaven, and other Mississippi communities. You can also consider remote and hybrid positions with employers hiring professionals based in the state.

How to Search Mississippi Jobs on Ladders

Explore current listings, compare responsibilities and compensation details, and focus your search on roles that match your skills and career goals. Tailor your résumé to highlight measurable results, leadership experience, and relevant expertise when applying.

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$175K - $250K *

Transform the GTM landscape by leading strategic initiatives, aligning teams, and driving measurable outcomes across solution areas. Foster collaboration and innovation to enhance sales processes and...

United StatesRemote

Reposted today

  •   8 - 10 years exp.  •   Information Technology

$103K - $181K *

Optimize project performance by managing cost, schedule, and risk metrics. Collaborate with teams to ensure accurate forecasting and reporting, driving efficiency across large capital construction pro...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Real Estate & Construction

$80K - $95K *

Drive growth by acquiring new customers for our innovative SaaS solutions. Leverage your sales expertise to engage decision-makers, understand their needs, and promote our Amplify Platform, focusing o...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Enterprise Technology

$80K - $95K *

Join a team that's dedicated to enhancing coding accuracy through comprehensive audits and educational support. Leverage your expertise in ICD-10, CPT, and HCPCS coding to drive compliance and improve...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Healthcare

$250K - $300K *

Elevate our presales organization by leading a global team focused on cybersecurity solutions. Drive technical wins, enhance sales effectiveness, and shape a high-performing culture that aligns with c...

United StatesRemote

Yesterday

  •   11 - 15 years exp.  •   Enterprise Technology

$120K - $145K *

Empower your career by leading the design and implementation of Oracle Field Service solutions for utility organizations. Collaborate with stakeholders to enhance operational performance and customer...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Staffing

$125K - $160K *

Join a team that's redefining data solutions by leading technical sales efforts, collaborating with Account Managers, and driving customer success through innovative data architecture and tailored dem...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Healthcare

$150K - $170K *

Take ownership of strategic finance leadership, optimizing cash flow and credit risk while developing innovative financing solutions to drive profitable growth and enhance operational efficiency acros...

United StatesRemote

6 days ago

  •   8 - 10 years exp.  •   Information Technology

$75K - $158K *

Champion the Alteryx platform by ensuring secure, efficient operations and integration across enterprise analytics. Collaborate with cross-functional teams to enhance data-driven decision-making and a...

RemoteRemote

Reposted 2 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$208K - $234K *

Drive the growth of Honeycomb Private Cloud by leading a senior engineering team, enhancing customer relationships, and ensuring operational excellence across multiple engineering domains. Collaborate...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Enterprise Technology

$88K - $115K *

Empower organizational change by analyzing stakeholder needs and implementing effective strategies. Collaborate with leadership and teams to enhance processes, ensuring smooth transitions and measurab...

RemoteRemote

Today

  •   8 - 10 years exp.  •   Business Services

$175K - $215K *

Transform client engagement by driving strategic growth and satisfaction through strong relationships and consultative solutions. Collaborate with cross-functional teams to deliver measurable business...

United StatesRemote

2 days ago

  •   5 - 7 years exp.  •   Information Technology

$175K - $215K *

Lead the charge in driving strategic growth and client satisfaction by managing senior-level relationships, leveraging cross-functional resources, and delivering measurable business value within a por...

United StatesRemote

6 days ago

  •   5 - 7 years exp.  •   Information Technology

$385K - $400K *

Transform regional sales performance by leading a high-impact team, driving strategic growth, and utilizing best practices to meet ambitious quotas within a dynamic environment. Foster relationships a...

RemoteRemote

Reposted 1 week ago

  •   Less than 5 years exp.  •   Information Technology

$110K - $130K *

Elevate your career by managing full life cycle subcontract activities, ensuring compliance, and driving supplier performance. Collaborate with cross-functional teams to optimize procurement strategie...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$180K - $240K *

Elevate your career by designing and building robust distributed systems. Lead architectural decisions, ensure reliability, and mentor engineers while tackling complex challenges in regulated environm...

United StatesRemote

4 weeks ago

  •   8 - 10 years exp.  •   Enterprise Technology

$100K - $120K *

Shape the future of clinical trials by driving business development initiatives, identifying opportunities with sponsors and CROs, and promoting CTSdatabase's services to enhance growth and profitabil...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$110K - $130K *

Champion strategic partnerships and drive revenue growth through effective channel management and collaborative business planning, ensuring sales success and partner satisfaction while navigating comp...

United StatesRemote

Reposted yesterday

  •   5 - 7 years exp.  •   Telecommunications & Hardware

$80K - $95K *

Transform customer data integration by configuring and validating mappings between third-party systems and applications. Collaborate with teams to ensure seamless onboarding and ongoing support, enhan...

United StatesRemote

2 days ago

  •   Less than 5 years exp.  •   Information Technology

$98K - $163K *

Shape your career by providing Tier III IT Systems support across enterprise technologies. Collaborate on projects, resolve complex challenges, and mentor junior engineers while ensuring operational e...

United StatesRemote

Yesterday

  •   5 - 7 years exp.  •   Information Technology

$153K - $171K *

Join a dynamic team to orchestrate complex technical programs, driving alignment and clarity across product and engineering. Empower teams to deliver impactful outcomes while leveraging AI insights fo...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Technical Services

$160K - $200K *

Optimize operational excellence and client service as a senior leader overseeing a complex Connected Solutions hub, ensuring high standards in production, technical operations, and team performance fo...

United StatesRemote

1 week ago

  •   11 - 15 years exp.  •   Media

$172K - $202K *

Lead the charge in delivering expert guidance on identity and access management technologies, focusing on architecting solutions and producing actionable research to enhance client performance and sec...

RemoteRemote

Reposted 2 weeks ago

  •   11 - 15 years exp.  •   Business Services

$90K - $125K *

Lead the development and submission of federal proposals, managing teams and resources to deliver compliant, compelling responses. Collaborate with cross-functional teams to ensure alignment with cust...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Technical Services

$110K - $130K *

Join a team that's dedicated to fostering strategic relationships with enterprise customers, ensuring successful adoption and optimization of technology solutions in the financial services sector whil...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Information Technology

Frequently Asked Questions (FAQ)

  • What types of $100,000+ jobs can I find in Mississippi?question toggle

    Listings may include senior roles in healthcare, technology, manufacturing, finance, energy, engineering, and management. Opportunities change over time, so check current listings for available positions.

  • Which Mississippi cities have high-paying job opportunities?question toggle

    Professional opportunities may be listed in Jackson, Gulfport, Biloxi, Hattiesburg, Southaven, and other parts of the state, depending on employer hiring needs.

  • Are remote jobs available to Mississippi residents?question toggle

    Some employers offer remote or hybrid positions that may be open to Mississippi-based candidates. Review each listing to confirm location and work arrangement requirements.

  • How can I qualify for a $100,000+ job in Mississippi?question toggle

    Requirements vary by role. Employers commonly seek relevant experience, specialized skills, and a record of strong results; senior positions may also require leadership experience or advanced credentials.