Discover professional opportunities in Mississippi with salaries of $100,000 or more. Ladders features vetted roles for experienced candidates seeking senior-level careers across the Magnolia State, from Jackson and the Gulf Coast to regional business hubs.
High-paying opportunities may be available in healthcare, technology, manufacturing, finance, energy, engineering, and executive leadership. Job availability and requirements vary by employer, location, and experience level, so review each listing for details.
Search roles in Jackson, Gulfport, Biloxi, Hattiesburg, Southaven, and other Mississippi communities. You can also consider remote and hybrid positions with employers hiring professionals based in the state.
Explore current listings, compare responsibilities and compensation details, and focus your search on roles that match your skills and career goals. Tailor your résumé to highlight measurable results, leadership experience, and relevant expertise when applying.
Senior Penetration Tester & Assessments Lead
$90K - $189K *
Lead, shape, and execute advanced penetration testing assessments, overseeing scoping, planning, and reporting. Collaborate with teams to enhance cybersecurity measures across various platforms, ensur...
Reposted 2 weeks ago
$88K - $132K *
Help us drive growth as a strategic Channel Account Manager, collaborating with partners to create scalable sales strategies, enhance engagement, and achieve measurable outcomes in the enterprise tech...
1 week ago
$120K - $145K *
Lead the charge in advancing AI applications in healthcare by developing intelligent agents that uncover financial opportunities within complex datasets, transforming manual analyses into scalable wor...
Yesterday
$75K - $107K *
Elevate customer relationships and drive revenue growth by managing complex Federal accounts. Collaborate with cross-functional teams to align strategies with customer needs, ensuring retention and ex...
1 week ago
$63K - $129K *
Shape your career by driving Agile execution excellence in federal HCM modernization. Lead cross-functional teams, facilitate SAFe ceremonies, and foster a continuous improvement culture within a larg...
Reposted yesterday
Substation Structural Engineer
$87K - $157K *
Lead the charge in designing and reviewing structural components for substation and transmission projects, ensuring quality control and mentoring junior engineers while engaging with clients and suppo...
5 days ago
$120K - $145K *
Join a dynamic team to drive technical success and adoption across enterprise accounts. Leverage your expertise in project management and technical execution to enhance deployment health and fuel acco...
Reposted yesterday
$110K - $130K *
Explore your career by building strategic partnerships in the life sciences sector. Drive account growth, develop client relationships, and connect with key stakeholders to enhance business opportunit...
Reposted 3 weeks ago
Software Engineer – AI Applications & ServiceNow
$100K - $130K *
Drive the design and deployment of secure AI applications in cloud environments, integrating advanced technologies like machine learning and ServiceNow solutions to enhance operational efficiency and...
2 weeks ago
$150K - $180K *
Shape the future of billing operations by leading a team to enhance accuracy, timeliness, and efficiency. Drive process improvements, manage complex accounts, and collaborate across functions to resol...
2 weeks ago
Manager, Customer Success Engineering
$124K - $210K *
Drive customer success by leading a team of engineers to enhance GitLab adoption, develop scalable enablement programs, and collaborate with cross-functional teams to achieve measurable business outco...
2 weeks ago
$110K - $130K *
Shape the future of client solutions by leveraging your technical expertise and business acumen. Collaborate with sales teams to design tailored solutions, deliver compelling presentations, and drive...
4 weeks ago
Principal Solutions Executive II - Security
$160K - $192K *
Accelerate revenue growth by driving security services sales, managing the full sales lifecycle, and building strategic relationships with clients and partners to enhance market presence and deliver i...
2 weeks ago
$110K - $130K *
Innovate healthcare delivery by developing AI solutions that enhance operations and resident experiences. Collaborate with teams to automate processes and improve clinical decision-making in senior ca...
1 month ago
Senior Account Executive, High Tech End User
$132K - $170K *
Transform client relationships and drive growth by consulting with C-level executives to implement strategic solutions that enhance value and satisfaction across major accounts, ensuring retention and...
6 days ago
$100K - $120K *
Transform the internal IT landscape by managing employee support, systems administration, and infrastructure scalability. Drive automation and security initiatives while enhancing user experience in a...
6 days ago
Senior Structural Engineer-Bridge
$88K - $154K *
Join a team that's redefining bridge engineering by delivering innovative designs and solutions. Collaborate on diverse projects, ensuring structural reliability and efficiency while enhancing your ex...
1 week ago
Director, Business Systems & Solution Architecture (D365 F&O)
$155K - $170K *
Lead the charge in shaping enterprise business solutions through hands-on architecture and delivery in Microsoft Dynamics 365 Finance & Operations, focusing on integration, process optimization, and o...
Reposted yesterday
Senior Implementation Consultant (Intacct)
$100K - $115K *
Partner with us to lead complex Sage Intacct implementations, guiding clients through analysis, design, and optimization. Leverage your expertise to enhance client relationships and drive successful p...
3 weeks ago
Director of SEC Reporting and Technical Accounting
$170K - $210K *
Shape the future of financial reporting by leading SEC compliance and technical accounting. Drive policy development, optimize processes, and collaborate with cross-functional teams to support growth...
1 week ago
$100K - $140K *
Lead the charge in architecting and building intelligent systems for autonomous GRC workflows, leveraging C#/.NET and Blazor to create scalable, high-performance solutions that drive innovation and ef...
Today
Technical Program Manager, Data Center Operations
$120K - $145K *
Engage in comprehensive program management for data center operations, ensuring seamless transitions from construction to live operations. Shape maintainability, drive incident improvements, and enhan...
Reposted yesterday
Senior Project Engineer - Multidisciplinary
$125K - $150K *
Drive impactful engineering solutions by leading a multidisciplinary team in delivering innovative projects across water and transportation sectors, ensuring quality and efficiency within budget and t...
2 weeks ago
$63K - $129K *
Contribute to system quality by executing test cases, analyzing requirements, and validating functionality to ensure compliance and stability in a fast-paced environment. Collaborate with teams to enh...
Reposted 2 weeks ago
Senior Manager, Web Optimization & Search Strategy
$120K - $145K *
Drive website optimization and search strategy initiatives, enhancing digital visibility and engagement. Collaborate with cross-functional teams to implement SEO, GEO, and technical strategies that el...
1 week ago
What types of $100,000+ jobs can I find in Mississippi?
Listings may include senior roles in healthcare, technology, manufacturing, finance, energy, engineering, and management. Opportunities change over time, so check current listings for available positions.
Which Mississippi cities have high-paying job opportunities?
Professional opportunities may be listed in Jackson, Gulfport, Biloxi, Hattiesburg, Southaven, and other parts of the state, depending on employer hiring needs.
Are remote jobs available to Mississippi residents?
Some employers offer remote or hybrid positions that may be open to Mississippi-based candidates. Review each listing to confirm location and work arrangement requirements.
How can I qualify for a $100,000+ job in Mississippi?
Requirements vary by role. Employers commonly seek relevant experience, specialized skills, and a record of strong results; senior positions may also require leadership experience or advanced credentials.