Mission Systems Engineer Jobs

At Ladders, we connect you with the best available Mission Systems Engineering jobs that pay over $100,000 a year. Mission Systems Engineers play an essential role in the development, operation, and application of both hardware and software systems in aerospace and defense sectors.

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With listings from a wide variety of industries, you can find a position that fits your unique skill set. Quality assured with vetted opportunities from leading companies.

Rise Above With Superior Positions

Aim for the stars with high salaried jobs in Mission Systems Engineering. Leverage your expertise to land a six-figure job that matches your career goals.

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$120K - $150K *

Join a dynamic team to optimize commercial pricing strategies, drive innovation, and support revenue growth within a leading tech integrator, enhancing the effectiveness of commercial practices across...

US-AnywhereRemote

Today

  •   8 - 10 years exp.  •   Business Services

$72K - $130K *

Lead the charge in optimizing Epic Hospital Billing configurations, ensuring quality and adherence to industry standards. Collaborate with cross-functional teams to translate user requirements and men...

US-AnywhereRemote

Yesterday

  •   Less than 5 years exp.  •   Healthcare

$160K - $185K *

Join a team that's pioneering AI evaluation and agent architecture, driving end-to-end solutions that enhance agent quality and performance. Collaborate with cross-functional teams to shape technical...

US-AnywhereRemote

Reposted 2 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$100K - $130K *

Join a dynamic team to lead a large-scale technology services program, ensuring seamless integration and customer satisfaction across a statewide IT environment. Drive collaboration and maintain execu...

US-AnywhereRemote

1 week ago

  •   8 - 10 years exp.  •   Information Technology

$105K - $120K *

Empower your career by leading a dynamic data analysis team, overseeing data management tasks, ensuring quality, and innovating through technical solutions to drive effective data reporting and suppor...

US-AnywhereRemote

1 week ago

  •   5 - 7 years exp.  •   Information Technology

$120K - $150K *

Join an innovative team as you lead AI security efforts, crafting secure frameworks for AI initiatives. Your expertise will shape the organization's AI strategies, ensuring robust security across all...

US-AnywhereRemote

3 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$149K - $185K *

Engage with Federal and Public Sector teams to develop targeted field programs, driving pipeline growth while navigating complex compliance and procurement needs to deliver measurable ROI and enhance...

US-AnywhereRemote

4 weeks ago

  •   5 - 7 years exp.  •   Education, Government & Non-Profit

$120K - $150K *

Partner with us to drive complex program delivery across global teams. Lead cross-functional collaborations, manage stakeholder relationships, and ensure continuous improvement in engineering excellen...

US-AnywhereRemote

5 days ago

  •   5 - 7 years exp.  •   Finance & Insurance

$90K - $120K *

Manage a team of Preconstruction specialists to lead project planning, budgeting, and risk assessments. Collaborate with clients and internal teams to ensure compliance with regulations and deliver ac...

US-AnywhereRemote

2 weeks ago

  •   5 - 7 years exp.  •   Real Estate & Construction

$140K - $175K *

Join our dynamic team as a Senior Customer Success Manager, driving customer satisfaction and product adoption through relationship building and expert guidance in cybersecurity solutions. Your role i...

US-AnywhereRemote

Yesterday

  •   5 - 7 years exp.  •   Enterprise Technology

$150K - $180K *

Help us develop innovative agentic platforms to enhance smart-home experiences, enabling systems that reason, maintain memory, and ensure safety while collaborating with cross-functional teams to deli...

US-AnywhereRemote

6 days ago

  •   5 - 7 years exp.  •   Information Technology

$217K - $303K *

Grow your career with our dynamic team leading innovative APIs and tooling for optimizing ad performance. Shape technical strategies and drive execution while developing talent in a collaborative envi...

US-AnywhereRemote

1 week ago

  •   5 - 7 years exp.  •   Enterprise Technology

$247K - $275K *

Champion innovative attack strategies for Oracle Cloud Infrastructure, driving offensive security research and development by collaborating with diverse teams. Build, document, and refine cloud attack...

US-AnywhereRemote

4 days ago

  •   8 - 10 years exp.  •   Enterprise Technology

$130K - $180K *

Partner with us to design and implement advanced security solutions leveraging AI, ensuring robust programs tailored to client needs while driving thought leadership within an evolving landscape...

US-AnywhereRemote

Yesterday

  •   8 - 10 years exp.  •   Information Technology

$100K - $130K *

Drive security enhancements by managing and deploying Swimlane solutions, providing technical leadership, and automating security workflows to optimize operations and enhance client security postures...

US-AnywhereRemote

1 week ago

  •   5 - 7 years exp.  •   Technical Services

$163K - $194K *

Drive the development of AI-native infrastructure solutions to support 200+ backend services. Collaborate on scalable platforms while managing complex reliability challenges. Leverage AI to enhance op...

US-AnywhereRemote

Today

  •   5 - 7 years exp.  •   Enterprise Technology

$100K - $130K *

Elevate your career by leading automation projects in the life sciences sector. Collaborate with cross-functional teams, provide technical guidance, and enhance client relationships to drive operation...

US-AnywhereRemote

Yesterday

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$110K - $130K *

Engage in managing and expanding a portfolio of technology partnerships, facilitating integrations that enhance client value. Work cross-functionally to optimize product offerings and track partnershi...

US-AnywhereRemote

3 weeks ago

  •   Less than 5 years exp.  •   Enterprise Technology

$90K - $140K *

Pioneer automation solutions that revolutionize engineering workflows through software development, CAD integration, and efficiency tools, empowering engineers in renewable energy and infrastructure p...

US-AnywhereRemote

2 weeks ago

  •   Less than 5 years exp.  •   Energy & Utilities

$70K - $95K *

Analyze and improve public health programs in a dynamic role that supports the Office of Suicide Prevention, providing critical insights and strategies to enhance effectiveness and drive impactful out...

US-AnywhereRemote

4 days ago

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$90K - $120K *

Discover the future of healthcare by managing complex, multi-site projects that drive organizational change and improve client relationships within clinical domains. Collaborate across teams to ensure...

US-AnywhereRemote

3 days ago

  •   5 - 7 years exp.  •   Healthcare

$90K - $130K *

Grow your expertise as you enhance cloud infrastructure automation, security delivery practices, and CI/CD pipelines while ensuring compliance with federal regulations in a dynamic, collaborative envi...

US-AnywhereRemote

6 days ago

  •   Less than 5 years exp.  •   Information Technology

$80K - $110K *

Transform client experiences by leading implementation projects and ensuring seamless integration of services while managing timelines, deliverables, and stakeholder communication effectively for opti...

US-AnywhereRemote

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$90K - $120K *

Lead the charge in managing a dynamic program team, ensuring compliance, driving performance, and fostering a collaborative workplace culture through coaching, development, and innovative training sol...

US-AnywhereRemote

Reposted 2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$92K - $125K *

Grow strategic relationships and drive sales for TE products with global Appliance OEMs. Leverage engineering insights to implement revenue-maximizing strategies and foster collaboration across teams...

US-AnywhereRemote

3 weeks ago

  •   Less than 5 years exp.  •   Business Services

Frequently Asked Questions (FAQ)

  • What does a Mission Systems Engineer do?question toggle

    A Mission Systems Engineer designs, maintains and enhances a variety of systems that are crucial for accomplishing a mission. This includes airborne systems, weapons systems, communication systems, and more.

  • How much can a Mission Systems Engineer earn?question toggle

    The salary for a Mission Systems Engineer can vary depending on experience and location, but jobs listed on Ladders pay $100,000 or more.

  • What types of companies hire Mission Systems Engineers?question toggle

    Industries such as Aerospace, Defense, IT, and Engineering Apps, among others, consistently need qualified Mission Systems Engineers.