Mission Systems Engineer Jobs

At Ladders, we connect you with the best available Mission Systems Engineering jobs that pay over $100,000 a year. Mission Systems Engineers play an essential role in the development, operation, and application of both hardware and software systems in aerospace and defense sectors.

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With listings from a wide variety of industries, you can find a position that fits your unique skill set. Quality assured with vetted opportunities from leading companies.

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Aim for the stars with high salaried jobs in Mission Systems Engineering. Leverage your expertise to land a six-figure job that matches your career goals.

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$66K - $106K *

Elevate your career by implementing secure DevSecOps practices in AWS GovCloud, enhancing CI/CD pipelines, and automating infrastructure. Collaborate across teams to optimize deployment patterns and m...

US-AnywhereRemote

Reposted 2 weeks ago

  •   5 - 7 years exp.  •   Aerospace & Defense

$157K - $283K *

Champion strategic capture management to drive high-value defense opportunities, crafting comprehensive plans and engaging with customers to secure success across pivotal projects within the Defense a...

US-AnywhereRemote

6 days ago

  •   8 - 10 years exp.  •   Aerospace & Defense

$120K - $160K *

Unlock potential by driving innovative, AI-powered financial audit solutions. Collaborate with cross-functional teams to design agent-driven experiences and own complex onboarding workflows for major...

US-AnywhereRemote

2 weeks ago

  •   Less than 5 years exp.  •   Finance & Insurance

$130K - $180K *

Join the forefront of AI innovation by architecting and leading the development of cutting-edge GenAI platforms. Shape the future of agentic workflows and LLM-backed services while mentoring a team of...

US-AnywhereRemote

6 days ago

  •   5 - 7 years exp.  •   Information Technology

$95K - $144K *

Join the AI Prototyping & Automation team to identify and prototype AI automation solutions, driving operational efficiency across the enterprise through hands-on analysis and AI tool utilization in a...

US-AnywhereRemote

2 weeks ago

  •   5 - 7 years exp.  •   Enterprise Technology

$125K - $174K *

Contribute to product vision and strategy by collaborating with cross-functional teams to deliver solutions that align with business goals, fostering a culture of Agile excellence and driving the life...

US-AnywhereRemote

6 days ago

  •   5 - 7 years exp.  •   Enterprise Technology

$92K - $154K *

Join us in transforming critical infrastructure! Lead the modernization of telecom systems, ensuring zero downtime while adhering to safety and compliance standards in a fast-paced, regulated environm...

US-AnywhereRemote

3 weeks ago

  •   8 - 10 years exp.  •   Energy & Utilities

$80K - $120K *

Unlock potential by transforming satellite-derived vegetation intelligence into actionable insights for utility customers while enhancing climate resilience and optimizing workflows with geospatial an...

US-AnywhereRemote

1 month ago

  •   Less than 5 years exp.  •   Energy & Utilities

$120K - $150K *

Champion data-driven insights by developing impactful AI systems that enhance healthcare reimbursement workflows, driving measurable business results through innovative applied engineering and collabo...

US-AnywhereRemote

4 days ago

  •   5 - 7 years exp.  •   Healthcare

$150K - $170K *

Join a team that's dedicated to delivering innovative network solutions. Collaborate with sales to design secure, scalable, and cost-effective architectures that meet client needs and drive business g...

US-AnywhereRemote

Reposted 1 week ago

  •   5 - 7 years exp.  •   Telecommunications & Hardware

$68K - $105K *

Unlock the potential of business systems through expert analysis, agile collaboration, and effective communication. Drive quality solutions while supporting daily operations and continuous improvement...

US-AnywhereRemote

Reposted 2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$151K *

Drive the quality assurance framework for clinical trials, ensuring regulatory compliance and operational excellence. Collaborate cross-functionally to enhance clinical quality and mitigate risks, ult...

US-AnywhereRemote

Reposted 3 days ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$120K - $150K *

Join a dynamic team as you lead manufacturing engineering efforts, driving expansive capacity growth and advanced process standardization for steel frame components across the global supply chain, ens...

US-AnywhereRemote

1 week ago

  •   11 - 15 years exp.  •   Manufacturing & Automotive

$185K - $232K *

Engineer comprehensive technical architectures and requirements for SaaS solutions. Lead collaborative sessions and drive design and integration efforts using Salesforce and best practices to optimize...

US-AnywhereRemote

3 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$100K - $130K *

Drive impactful internal projects by leading cross-functional teams, managing budgets, and schedules from inception to delivery. Collaborate with stakeholders to streamline services while ensuring com...

US-AnywhereRemote

3 days ago

  •   5 - 7 years exp.  •   Healthcare

$112K - $193K *

Join a team that's shaping the future of healthcare technology. As a Backend Tech Lead, you'll drive backend platform design, deliver scalable software solutions, and mentor engineers while ensuring h...

US-AnywhereRemote

Reposted 5 days ago

  •   5 - 7 years exp.  •   Information Technology

$116K - $162K *

Champion enterprise application delivery platforms to ensure optimal performance, availability, and resiliency. Lead complex issue resolution and drive continuous improvement initiatives in high-avail...

US-AnywhereRemote

Reposted today

  •   Less than 5 years exp.  •   Information Technology

$123K - $170K *

Lead transformative software development initiatives by leveraging your expertise in Salesforce and cloud technologies, driving performance and best practices while mentoring diverse teams to achieve...

US-AnywhereRemote

Reposted 4 days ago

  •   5 - 7 years exp.  •   Information Technology

$70K - $95K *

Manage the full contract lifecycle in a fast-paced federal environment, ensuring compliance, mitigating risks, and collaborating with teams to support critical government programs. Great opportunity f...

US-AnywhereRemote

3 days ago

  •   Less than 5 years exp.  •   Legal & Accounting

$90K - $95K *

Elevate organizational efficiency by managing complex data and finances, tackling administrative challenges, and coordinating projects with minimal supervision. Your expertise will support key decisio...

US-AnywhereRemote

1 week ago

  •   Less than 5 years exp.  •   Business Services

$142K - $196K *

Lead the integration of AI in Healthcare Information Systems, establishing release strategies and operational standards while ensuring compliance and reliability in a high-stakes environment. Drive in...

US-AnywhereRemote

1 week ago

  •   8 - 10 years exp.  •   Healthcare

$100K - $130K *

Lead logistics initiatives by managing Integrated Product Support programs, ensuring customer demands are met while maintaining quality, cost, and schedule objectives. Collaborate with engineering and...

US-AnywhereRemote

Yesterday

  •   11 - 15 years exp.  •   Aerospace & Defense

$183K - $263K *

Shape the future of ASIC packaging by leading signal and power integrity efforts. Collaborate with cross-functional teams to develop innovative solutions, ensuring design excellence and performance in...

US-AnywhereRemote

3 weeks ago

  •   Less than 5 years exp.  •   Telecommunications & Hardware

$289K - $340K *

Deliver innovative solutions in defense sales, expanding Air Force accounts while leveraging extensive industry knowledge and strategic relationships to meet client needs and drive revenue growth...

US-AnywhereRemote

Yesterday

  •   8 - 10 years exp.  •   Aerospace & Defense

$81K - $138K *

Deliver impact by ensuring compliance and enhancing program efficiency through expertise in monitoring and analysis, while supporting federal initiatives to improve services for refugees and vulnerabl...

US-AnywhereRemote

4 days ago

  •   5 - 7 years exp.  •   Education, Government & Non-Profit

Frequently Asked Questions (FAQ)

  • What does a Mission Systems Engineer do?question toggle

    A Mission Systems Engineer designs, maintains and enhances a variety of systems that are crucial for accomplishing a mission. This includes airborne systems, weapons systems, communication systems, and more.

  • How much can a Mission Systems Engineer earn?question toggle

    The salary for a Mission Systems Engineer can vary depending on experience and location, but jobs listed on Ladders pay $100,000 or more.

  • What types of companies hire Mission Systems Engineers?question toggle

    Industries such as Aerospace, Defense, IT, and Engineering Apps, among others, consistently need qualified Mission Systems Engineers.