Mission Systems Engineer Jobs

At Ladders, we connect you with the best available Mission Systems Engineering jobs that pay over $100,000 a year. Mission Systems Engineers play an essential role in the development, operation, and application of both hardware and software systems in aerospace and defense sectors.

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With listings from a wide variety of industries, you can find a position that fits your unique skill set. Quality assured with vetted opportunities from leading companies.

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Aim for the stars with high salaried jobs in Mission Systems Engineering. Leverage your expertise to land a six-figure job that matches your career goals.

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$114K - $252K *

Transform your career by leading the support and management of Microsoft 365 environments. Collaborate with cross-functional teams to deliver exceptional service for SharePoint, Teams, and Power Platf...

US-AnywhereRemote

4 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$110K - $130K *

Empower federal clients by administering high-availability ArcGIS Enterprise platforms in cloud environments. Lead design and automation efforts in AWS, ensuring optimal performance and compliance whi...

US-AnywhereRemote

Today

  •   5 - 7 years exp.  •   Information Technology

$100K - $120K *

Manage third-party vendor performance for clinical research studies, ensuring compliance with GCP and ICH guidelines. Coordinate cross-functional teams and oversee budgets while maintaining quality se...

US-AnywhereRemote

6 days ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$75K - $158K *

Engage in pivotal analysis and support for financial system interfaces, driving modernization efforts for the Department of Veterans Affairs. Collaborate with teams to streamline data processes and en...

US-AnywhereRemote

Reposted 2 weeks ago

  •   5 - 7 years exp.  •   Education, Government & Non-Profit

$85K - $105K *

Shape innovative solutions by partnering with sales teams to design scalable, client-oriented technologies that enhance business success and ensure seamless implementation and long-term adoption acros...

US-AnywhereRemote

4 weeks ago

  •   5 - 7 years exp.  •   Enterprise Technology

$132K - $251K *

Empower global mobility strategies by leading initiatives for the internationally mobile workforce, ensuring compliance and governance while enhancing processes and technology to streamline operations...

US-AnywhereRemote

Reposted 6 days ago

  •   5 - 7 years exp.  •   Business Services

$120K - $160K *

Lead the financial planning and analysis for multiple programs, ensuring effective project control and performance tracking while mentoring junior staff in a fast-paced environment. Influence operatio...

US-AnywhereRemote

2 weeks ago

  •   11 - 15 years exp.  •   Aerospace & Defense

$170K - $190K *

Unlock innovative biosignal solutions by leading algorithm development, enhancing machine learning tools, and engaging with stakeholders to improve health-related therapies in a collaborative remote t...

US-AnywhereRemote

2 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$150K - $180K *

Tackle complex challenges as you optimize, configure, and enhance the Atlassian tool suite, streamlining workflows and driving mission success for federal clients through collaboration and technical e...

US-AnywhereRemote

3 days ago

  •   5 - 7 years exp.  •   Technical Services

$100K - $120K *

Lead and oversee commissioning activities for data center projects, ensuring alignment with project specifications, operational readiness, and stakeholder engagement across the project lifecycle. Driv...

US-AnywhereRemote

1 week ago

  •   5 - 7 years exp.  •   Technical Services

$125K - $135K *

Shape the future of military communications by leading multi-disciplinary teams, engaging with senior Army and National Guard leaders to develop innovative tech solutions that enhance operational effe...

US-AnywhereRemote

Yesterday

  •   8 - 10 years exp.  •   Aerospace & Defense

$66K - $106K *

Help us maximize value by overseeing Agile teams in maintaining the Medicare claims processing system, ensuring stakeholder alignment and delivering high-quality outcomes within a structured SAFe Agil...

US-AnywhereRemote

3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$80K - $110K *

Manage diverse technology projects end-to-end, collaborating with Technical Leads to ensure successful client outcomes and adapting methodologies to fit each unique engagement's needs...

US-AnywhereRemote

1 week ago

  •   Less than 5 years exp.  •   Business Services

$88K - $154K *

Join a team that's redefining process engineering in semiconductor water treatment. Leverage your expertise in ultrapure water and wastewater systems to design, optimize, and implement essential solut...

US-AnywhereRemote

3 weeks ago

  •   8 - 10 years exp.  •   Manufacturing & Automotive

$100K - $120K *

Support, troubleshoot, and validate operational workflows in clinical AI integrations, enhancing healthcare technology interfaces and driving innovation through structured testing methodologies and st...

US-AnywhereRemote

Yesterday

  •   5 - 7 years exp.  •   Healthcare

$87K - $161K *

Elevate your career by designing and implementing advanced IAM solutions. Join us as a key technical expert driving secure identity management across various platforms, while collaborating with securi...

US-AnywhereRemote

Today

  •   Less than 5 years exp.  •   Information Technology

$141K - $224K *

Optimize PCB technologies and collaborate across teams to ensure robust designs. Lead reviews, enhance manufacturing processes, and solve issues to deliver reliable systems for aerospace and military...

US-AnywhereRemote

5 days ago

  •   8 - 10 years exp.  •   Aerospace & Defense

$110K - $130K *

Join our team to lead the design and implementation of Manufacturing Execution Systems (MES) for the biotech and pharmaceutical industries. Collaborate with clients and teams to enhance operational ef...

US-AnywhereRemote

3 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$76K - $151K *

Drive innovative solutions in data management, utilizing Python and SQL to enhance financial operations, support audit readiness, and advance analytics for federal clients, collaborating with cross-fu...

US-AnywhereRemote

Yesterday

  •   5 - 7 years exp.  •   Aerospace & Defense

$120K - $146K *

Join our team to design and maintain scalable data pipelines that integrate health, financial, and operational data for the Military Health System, improving data access and utilization across diverse...

US-AnywhereRemote

1 week ago

  •   Less than 5 years exp.  •   Information Technology

$120K - $146K *

Advance your career by designing and optimizing data pipelines for healthcare analytics. Collaborate with multidisciplinary teams to transform data into actionable insights and enhance operational dec...

US-AnywhereRemote

1 week ago

  •   Less than 5 years exp.  •   Information Technology

$88K - $139K *

Optimize technical support for government and commercial systems, driving customer satisfaction through remote and onsite assistance in a collaborative environment. Engage with diverse teams to ensure...

US-AnywhereRemote

1 week ago

  •   5 - 7 years exp.  •   Aerospace & Defense

$116K - $210K *

Join a dynamic team as we manage high voltage transmission projects, providing engineering expertise and mentorship while utilizing advanced technologies to enhance design efficiency and client satisf...

US-AnywhereRemote

2 weeks ago

  •   11 - 15 years exp.  •   Energy & Utilities

$137K - $185K *

Transform the future of aerospace manufacturing as a key engineer focused on test deployment and optimization at CM sites, enhancing satellite PCBAs with innovative strategies and hands-on problem-sol...

US-AnywhereRemote

Reposted 1 week ago

  •   8 - 10 years exp.  •   Aerospace & Defense

$122K - $211K *

Deliver cutting-edge AI/ML solutions to support critical operations, optimizing predictive models and real-time decision-making. Collaborate within a cross-functional team, implementing best practices...

US-AnywhereRemote

2 weeks ago

  •   5 - 7 years exp.  •   Aerospace & Defense

Frequently Asked Questions (FAQ)

  • What does a Mission Systems Engineer do?question toggle

    A Mission Systems Engineer designs, maintains and enhances a variety of systems that are crucial for accomplishing a mission. This includes airborne systems, weapons systems, communication systems, and more.

  • How much can a Mission Systems Engineer earn?question toggle

    The salary for a Mission Systems Engineer can vary depending on experience and location, but jobs listed on Ladders pay $100,000 or more.

  • What types of companies hire Mission Systems Engineers?question toggle

    Industries such as Aerospace, Defense, IT, and Engineering Apps, among others, consistently need qualified Mission Systems Engineers.