Discover Microsoft Systems Engineer jobs with organizations seeking experienced professionals to design, implement, and support enterprise technology environments. These roles bring together expertise in Microsoft platforms, infrastructure, cloud services, security, and end-user computing. Ladders features vetted professional opportunities paying $100,000 or more, including positions for engineers who can keep complex systems reliable, secure, and ready to scale.
Microsoft Systems Engineers plan and maintain the systems that organizations rely on every day. Depending on the employer, responsibilities may include administering Windows Server environments, managing Microsoft 365 and Azure services, supporting identity and access management, automating deployments, and resolving infrastructure issues. Engineers may also contribute to architecture decisions, disaster recovery planning, endpoint management, and technical documentation.
Employers commonly look for hands-on experience with Microsoft technologies such as Windows Server, Active Directory or Microsoft Entra ID, Microsoft 365, Azure, and PowerShell. Knowledge of networking, virtualization, cloud operations, cybersecurity, and systems monitoring can strengthen an application. Clear communication and the ability to collaborate across IT, security, and business teams are also important, especially in senior and enterprise roles. Relevant Microsoft certifications may help demonstrate specialized expertise.
Microsoft Systems Engineers work across industries, including technology, finance, healthcare, manufacturing, and government. Career paths can lead to senior systems engineering, cloud engineering, infrastructure architecture, technical leadership, or IT management. The right opportunity depends on your platform expertise, preferred work environment, and whether you want to focus on cloud migration, enterprise operations, security, or automation.
Use Ladders to explore vetted Microsoft Systems Engineer opportunities paying $100,000 or more. Review job requirements, compare roles, and identify positions that align with your experience in Microsoft infrastructure and enterprise systems. New listings may be added regularly, so check back to find opportunities suited to your next career move.
$73K - $102K *
Unlock potential by leading the development of LLM-powered applications and agentic systems. Collaborate across teams to design, implement, and maintain innovative software solutions, ensuring high qu...
2 weeks ago
Senior Structural Engineer, Data Centers - Remote (U.S.)
$110K - $130K *
Join a dynamic team as a Senior Structural Engineer, leading innovative design for hyperscale data centers. Leverage your expertise in concrete and steel structures to deliver impactful projects while...
2 weeks ago
$140K - $185K *
Transform project delivery by managing IT initiatives for California agencies. Collaborate with state staff to ensure timely, budget-compliant outcomes while leveraging Agile methodologies and large s...
1 week ago
$110K - $130K *
Manage clinical operations for low to moderate complexity studies, ensuring timely delivery of clean data while adhering to quality and budget expectations. Collaborate with teams to meet project goal...
3 days ago
Field Service Engineer II, LCMS - SF Bay Area, CA
$72K - $93K *
Lead the charge in delivering top-tier service for advanced analytical instruments. Collaborate with diverse clients across research and healthcare to install, maintain, and repair cutting-edge equipm...
Reposted 3 weeks ago
Manager II, Engineering- Analytics Engineering, Core Data Science
$177K - $364K *
Join a high-performance analytics team to enhance data foundations, tooling, and insights. Collaborate cross-functionally to shape innovative products and ensure data quality and democratization while...
3 weeks ago
Project Manager - Field Service
$90K - $110K *
Pioneer procurement excellence by managing supplier relationships and project timelines, while ensuring the effective acquisition of resources for seamless operations and continuous supply chain impro...
Reposted 4 weeks ago
$80K - $90K *
Analyze and deliver data management solutions to support public health research, utilizing advanced statistical software and collaborating with project leaders to enhance data quality and reporting fo...
2 weeks ago
$90K - $110K *
Empower your career by driving project delivery and managing Agile teams. Utilize AI tools to enhance decision-making, anticipate risks, and ensure timely outcomes. Collaborate with stakeholders to ma...
2 weeks ago
Technical Leader - EMF Engineer
$115K - $130K *
Unlock your potential by leading research on electric and magnetic fields (EMF) and RF exposure. Collaborate with utilities and stakeholders to develop solutions and technical guidance for emerging en...
5 days ago
$75K - $112K *
Unlock potential by managing complex billing processes and leading a team to ensure accurate invoicing and exceptional customer service. Collaborate across departments to drive efficiency and implemen...
3 days ago
Regional Technical Leader - North Region (US)
$100K - $120K *
Empower teams by enhancing technical capabilities across multiple sites, driving operational excellence through hands-on training and support. Engage in troubleshooting and continuous improvement to e...
2 weeks ago
Head of Advanced Mathematical Modelling
$150K - $180K *
Champion advanced mathematical modelling by leading a high-performing team, driving innovation, and solving complex supply chain challenges through optimization, AI/ML, and decision science to shape b...
3 weeks ago
Advanced Specialist, Project Management
$125K - $135K *
Lead the strategic planning and execution of complex programs across multiple teams, ensuring alignment with business priorities and effective risk management. Drive delivery improvements and maintain...
Reposted 3 days ago
Complex Delivery Program Manager IRC297187
$160K - $220K *
Shape the future of project management by leading high-stakes engagements, driving AI adoption, and ensuring quality deliverables in a dynamic, remote-compatible environment. Collaborate with diverse...
1 week ago
$100K - $108K *
Transform proposal processes by coordinating comprehensive responses to client requests, ensuring quality and compliance while leveraging AI technologies to enhance business development in the Space...
3 weeks ago
$120K - $140K *
Drive the development and optimization of GTM strategies, leveraging automation and campaign execution across multiple platforms to enhance pipeline generation and account prioritization in a dynamic...
Reposted 4 days ago
$185K - $297K *
Elevate your engineering career by leading test automation and quality architecture for cloud and mobile systems. Shape technical vision, mentor engineers, and drive AI-first automation strategies whi...
Reposted 2 weeks ago
$90K - $110K *
Join our team to enhance security and automation in delivery pipelines, driving consistent deployments and compliance through modern DevSecOps practices alongside skilled professionals...
Reposted 3 weeks ago
Senior Advisor, Regulatory Starting Material
$153K - $268K *
Join a team that's advancing regulatory strategies for drug substance manufacturing. Lead the charge in selecting and justifying Regulatory Starting Materials, ensuring compliance with global guidelin...
Reposted 4 days ago
Engineering Technical Lead - I&C Embedded Software
$113K - $188K *
Contribute to the development of embedded software for nuclear systems. Lead a team ensuring design compliance, execute project plans, and enhance operational efficiency. Drive collaboration across di...
Reposted 1 week ago
Pension Administration - Senior Specialist
$74K - $148K *
Shape the future of pension administration by leading special projects and ensuring successful data management while collaborating with diverse teams to meet client expectations and drive growth in Bu...
3 weeks ago
Global HSE Industrial Hygiene Manager
$94K - $224K *
Lead the charge in developing and managing global industrial hygiene programs, ensuring compliance with HSE laws and fostering a culture of safety. Collaborate with stakeholders to enhance health and...
3 days ago
Associate Director, Project Management
$117K - $189K *
Pioneer global Orexin development programs by driving project management efforts. Partner with the Global Team Leader to oversee cross-functional teams, manage critical activities, and ensure project...
Reposted today
Systems Engineering Lead/Manager - KSA C4I
$161K - $299K *
Transform the future of C4I systems as a Systems Engineering Manager, leading design initiatives and managing a team to ensure alignment with customer requirements. Drive modernization efforts through...
1 week ago
What does a Microsoft Systems Engineer do?
A Microsoft Systems Engineer designs, operates, and improves technology environments built on Microsoft platforms. Common work includes managing Windows Server, Microsoft 365, Azure, identity services, security controls, automation, and infrastructure support.
What skills are needed for Microsoft Systems Engineer jobs?
Commonly requested skills include Windows Server administration, Microsoft 365, Azure, Active Directory or Microsoft Entra ID, PowerShell, networking, virtualization, troubleshooting, and security fundamentals. Requirements vary by role and employer.
Do Microsoft Systems Engineers need certifications?
Certifications are not required for every position, but relevant Microsoft credentials can help demonstrate platform knowledge. Employers may value certifications related to Azure, Microsoft 365, identity, security, or administration, alongside practical experience.
How much do Microsoft Systems Engineer jobs pay?
Compensation varies by experience, location, industry, and role scope. Ladders focuses on vetted professional jobs paying $100,000 or more, where available salary information and requirements are listed with each opportunity.
Where can I find Microsoft Systems Engineer jobs paying $100,000 or more?
Explore Microsoft Systems Engineer listings on Ladders to find vetted professional opportunities with salaries of $100,000 or more. Compare job responsibilities and qualifications to identify roles that fit your background.