Welcome to Information Systems Security Officer (ISSO) Jobs

As an Information Systems Security Officer (ISSO), you play a critical role in protecting an organization's information system. Discover opportunities that pay over $100k, exclusively available on Ladders.

Job responsibilities

As an ISSO, your responsibilities can include ensuring system security, conducting regular checks, and implementing the organization's security policy.

Skills Needed

Successful ISSOs often have strong technical abilities, knowledge of IT security, problem-solving skills, and an understanding of relevant laws and regulations.

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Compensation
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Position Level
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$65K - $101K *

Join a team that's dedicated to navigating and advancing regulatory affairs in clinical research. Utilize your expertise to ensure compliance with federal regulations while collaborating with investig...

US-AnywhereRemote

5 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$150K - $180K *

Lead the charge in shaping cloud-native architecture and agentic AI systems. Drive infrastructure excellence at scale while mentoring engineers and establishing DevOps standards to enhance organizatio...

US-AnywhereRemote

1 week ago

  •   8 - 10 years exp.  •   Information Technology

$120K - $180K *

Help us enhance customer satisfaction and retention by leading support operations and strategic initiatives. Oversee technical issue resolution and foster collaboration across multiple teams to optimi...

US-AnywhereRemote

5 days ago

  •   5 - 7 years exp.  •   Technical Services

$90K - $130K *

Lead the charge in advancing database strategies, overseeing on-premises and cloud operations, and ensuring security and efficiency while collaborating on innovative solutions to enhance data manageme...

US-AnywhereRemote

2 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$75K - $95K *

Partner with us to enhance governance and operational effectiveness through independent auditing and advisory services. Contribute to organizational integrity by evaluating risk management and interna...

US-AnywhereRemote

Reposted 3 days ago

  •   5 - 7 years exp.  •   Legal & Accounting

$156K - $208K *

Elevate your career by leading the transformation of a contingent workforce program. Collaborate with senior leaders to enhance processes and develop governance strategies, ensuring operational excell...

US-AnywhereRemote

6 days ago

  •   5 - 7 years exp.  •   Staffing

$119K - $148K *

Empower enterprise customers in navigating security transformations, driving software adoption, and shaping effective DevSecOps strategies. Forge trusted relationships that transform security obstacle...

US-AnywhereRemote

3 weeks ago

  •   5 - 7 years exp.  •   Enterprise Technology

$128K - $136K *

Lead the charge in optimizing clinical research studies through training and support, ensuring compliance, and fostering collaboration across teams to achieve successful trial outcomes and enhance pat...

US-AnywhereRemote

3 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$128K - $136K *

Join an innovative clinical research team to enhance study efficiency through training, protocol interpretation, and overall trial support, ensuring compliance and safety for research subjects...

US-AnywhereRemote

3 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$84K - $152K *

Unlock potential by leading Level 2-3 technical support, mentoring junior engineers, and collaborating with cross-functional teams to resolve complex issues. Drive product enhancements and contribute...

US-AnywhereRemote

3 days ago

  •   5 - 7 years exp.  •   Technical Services

$74K - $130K *

Unlock potential by joining a dynamic team to manage project controls, analyze financial data, and ensure compliance across diverse contract types while enhancing budget performance and fostering coll...

US-AnywhereRemote

1 week ago

  •   5 - 7 years exp.  •   Technical Services

$130K - $140K *

Engineer procurement excellence by leading supplier management, contract negotiations, and technology integration. Collaborate across departments to optimize sourcing strategies and enhance operationa...

US-AnywhereRemote

6 days ago

  •   5 - 7 years exp.  •   Business Services

$130K - $208K *

Advance your career by leading a Salesforce team to deliver innovative solutions, enhance application architecture, and strengthen partnerships across the organization to meet business objectives and...

US-AnywhereRemote

2 weeks ago

  •   8 - 10 years exp.  •   Enterprise Technology

$120K - $140K *

Drive impactful Revenue Operations through advanced analysis, enhancing GTM systems and reporting to support sales efficiency and revenue performance. Collaborate cross-functionally, leveraging techni...

US-AnywhereRemote

1 week ago

  •   5 - 7 years exp.  •   Business Services

$112K - $179K *

Champion agile practices by leading Scrum teams, prioritizing tasks, and facilitating collaboration. Drive effective project execution, ensuring compliance with software methodologies while fostering...

US-AnywhereRemote

5 days ago

  •   Less than 5 years exp.  •   Information Technology

$112K - $179K *

Join a team that's guiding Agile projects to success. Lead Scrum practices, support cross-functional collaboration, and ensure timely code releases and integrations within a fast-paced environment, wh...

US-AnywhereRemote

1 week ago

  •   Less than 5 years exp.  •   Information Technology

$63K - $111K *

Optimize subcontract administration to ensure compliance, enhance relationships, and manage proposal evaluations. Collaborate with internal teams and subcontractors to drive project success and mainta...

US-AnywhereRemote

1 week ago

  •   Less than 5 years exp.  •   Aerospace & Defense

$145K - $231K *

Join a strategic team to lead the third-party risk management program across a national bank. You will oversee vendor assessments and compliance, enhance frameworks, and ensure regulatory readiness wh...

US-AnywhereRemote

3 days ago

  •   5 - 7 years exp.  •   Finance & Insurance

$200K - $230K *

Develop strategic channel partnerships to drive growth, enhance partner success, and execute marketing initiatives. Collaborate with sales teams and align strategies to achieve pipeline and booking ta...

US-AnywhereRemote

6 days ago

  •   5 - 7 years exp.  •   Information Technology

$85K - $104K *

Join a team that's dedicated to delivering successful projects by managing resources, budgets, and stakeholder communication. Lead cross-functional efforts in IT and business to align with strategic g...

US-AnywhereRemote

1 week ago

  •   5 - 7 years exp.  •   Healthcare

$75K - $95K *

Elevate technical support by providing leadership and expertise in resolving complex issues in advanced scientific instrumentation. Foster collaboration among global teams to enhance system performanc...

US-AnywhereRemote

2 weeks ago

  •   5 - 7 years exp.  •   Technical Services

$93K - $137K *

Partner with us to optimize industrial water treatment programs, enhancing system performance and customer relationships through expertise in troubleshooting and technical management. Drive continuous...

US-AnywhereRemote

4 weeks ago

  •   Less than 5 years exp.  •   Energy & Utilities

$105K - $130K *

Partner with us to deliver expert information security consulting and compliance services. Assess organizational practices against industry standards and drive remediation efforts to uphold privacy an...

US-AnywhereRemote

3 days ago

  •   5 - 7 years exp.  •   Technical Services

$149K - $248K *

Accelerate progress at the forefront of healthcare IT by supporting a dynamic PMO with expertise in project management, governance, and stakeholder engagement to ensure timely delivery across multi-ag...

US-AnywhereRemote

4 days ago

  •   5 - 7 years exp.  •   Healthcare

$106K - $176K *

Drive enterprise contract management excellence by leading the strategic optimization, governance, and integrity of CLM solutions, collaborating across teams to translate business needs into scalable...

US-AnywhereRemote

2 weeks ago

  •   8 - 10 years exp.  •   Enterprise Technology

Frequently Asked Questions (FAQ)

  • What is the role of an Information Systems Security Officer (ISSO)?question toggle

    An ISSO is responsible for ensuring the confidentiality and integrity of an organization's information system. They implement the organization's IT security policies and conduct regular checks and audits.

  • What skills do you need for ISSO jobs?question toggle

    ISSOs need strong technical abilities, knowledge of IT security, problem-solving skills, and an understanding of relevant laws and regulations.

  • What kind of ISSO jobs are available on Ladders?question toggle

    Ladders offers a variety of high-paying ISSO jobs from reputable companies that value your skills and experience.