Information Systems Security Officers help organizations protect sensitive data, systems, and networks. ISSOs assess security risks, guide teams through compliance requirements, and help ensure that information systems are designed and operated securely. Explore vetted ISSO opportunities on Ladders, including professional roles that pay $100,000 or more.
Responsibilities vary by employer and industry, but ISSOs commonly maintain security documentation, monitor system controls, coordinate risk assessments, and support authorization and compliance activities. They may work with system owners, security engineers, auditors, and government stakeholders to identify vulnerabilities and address findings.
Employers often seek experience in information security, risk management, security controls, and regulatory or government frameworks. Familiarity with standards such as NIST guidance, authorization processes, incident response, and security assessment practices can be valuable. Some roles require a bachelor’s degree, relevant certifications, security clearance, or experience supporting federal systems; requirements differ by position.
ISSO professionals work across government contracting, defense, technology, healthcare, financial services, and other sectors with complex security needs. Depending on experience, they may advance into senior ISSO, information assurance, cybersecurity program management, or security leadership roles. Browse current listings to compare responsibilities, qualifications, work arrangements, and compensation.
Use Ladders to explore vetted professional opportunities, including Information Systems Security Officer jobs with salaries of $100,000 or more. Review each listing for its specific pay range, location, clearance requirements, and experience expectations, then apply to roles aligned with your background.
Claims Systems Manager (Remote)
$99K - $129K *
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Sales Account Manager - Eastern US
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Manager, Enterprise Data Integration & Insights-IT
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Manage and lead cross-functional teams to design and deliver data integration solutions, ensuring agile, secure, and scalable data platforms that drive analytics and insights for informed decision-mak...
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Senior Manager, Partner Technology Architecture
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Strategic Alliance Manager – Defense Tech
$195K - $266K *
Champion strategic partnerships in defense technology, driving innovation and collaboration. Lead the entire partner lifecycle, from recruitment to monetization, ensuring mission success through effec...
2 weeks ago
Director of Social Media Operations - Remote
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Shape the future of social media strategy and operations by leading enterprise-wide governance, optimizing processes, and driving engagement across teams to enhance digital communications and operatio...
3 days ago
Customer Success Manager (Public Sector)
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Join a team that's dedicated to enhancing customer success in cybersecurity. Leverage your expertise to build trusted relationships, drive product adoption, and ensure client satisfaction while naviga...
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Senior Contract Manager - Suppliers & Third Parties
$120K - $150K *
Empower stakeholders by leading the complete contracting lifecycle for strategic suppliers and partners. Collaborate cross-functionally to negotiate complex agreements, manage risks, and optimize cont...
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$90K - $230K *
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Empower cross-functional collaboration by aligning technology with business priorities. Drive strategic initiatives, enhance cybersecurity compliance, and foster trusted relationships to optimize ente...
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Unlock potential by serving as a strategic liaison between Finance, Facilities, and Supply Chain functions and IT, ensuring alignment of technology capabilities with business priorities and driving su...
3 days ago
Manager, Training Delivery (Remote)
$110K - $160K *
Join a team that's dedicated to enhancing global security by leading the delivery of innovative training programs. You'll mentor instructors, manage operations, and collaborate with cross-functional t...
2 weeks ago
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Unlock your potential by joining a dynamic team focused on federal acquisitions. Leverage your expertise to navigate the acquisition lifecycle, solve complex challenges, and contribute to impactful pr...
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Sr. Account Manager - Cybersecurity | New England
$110K - $130K *
Drive strategic account management by building relationships, executing multi-year plans, and enhancing client satisfaction within assigned accounts, leveraging cross-functional teams to achieve cyber...
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$74K - $139K *
Engage in comprehensive contracts management, coordinating across multiple departments to optimize proposals, negotiations, and compliance while fostering customer relationships and ensuring adherence...
1 month ago
Privileging Manager - Healthcare (Remote)
$80K - $95K *
Lead the charge in credentialing excellence by managing a remote team that ensures timely hospital privileges for healthcare providers, enhancing patient access to critical specialty care across the n...
3 weeks ago
$73K - $103K *
Support a global workforce by delivering exceptional IT solutions. Manage user lifecycle processes, troubleshoot modern workplace technologies, and enhance IT operations through automation and documen...
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Service Performance / SLA Analyst (Journeyman)
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Lead the charge in performance measurement and service-level governance, analyzing data to enhance service quality and efficiency. Collaborate with stakeholders to develop actionable insights and main...
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Champion client success by leading post-sale implementations and ensuring ongoing account performance. Collaborate with cross-functional teams to translate client needs into actionable insights, drivi...
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Governance Engineer II - Remote
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Make your mark at the forefront of API and AI governance, driving automation and compliance. Collaborate with cross-functional teams to implement standards and enhance security, ensuring responsible i...
2 weeks ago
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Drive impactful initiatives by leading complex workstreams that enhance performance, reduce costs, and mitigate risks. Collaborate across teams to influence outcomes and implement strategic improvemen...
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Senior Software Engineer, Identity & Access Discovery
$135K - $160K *
Engineer resilient backend solutions for privileged account discovery, enhancing security while navigating complex, customer-deployed environments. Collaborate on data-processing workflows using cutti...
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Deployment Lead - ERP Solutions
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Lead the charge in ERP implementation, guiding customer onboarding, deploying solutions, and driving alignment across teams to optimize finance transformations and enhance customer experiences in a dy...
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Site Contracts Specialist II or Sr. Site Contracts Specialist
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What is an Information Systems Security Officer (ISSO)?
An ISSO is a cybersecurity professional who helps protect an organization’s information systems by coordinating security controls, assessing risks, maintaining documentation, and supporting compliance and authorization activities.
What qualifications are commonly required for ISSO jobs?
Requirements vary, but employers commonly look for information security or IT experience, knowledge of security controls and risk management, and familiarity with relevant standards such as NIST guidance. Some positions may require a degree, professional certifications, or an active security clearance.
How much do Information Systems Security Officers earn?
Compensation varies by employer, location, experience, clearance, and job scope. Ladders focuses on vetted professional jobs paying $100,000 or more; check each listing for its stated salary or compensation details.
Where do ISSOs work?
ISSO roles are found in government and defense contracting, technology, healthcare, financial services, and other industries that manage sensitive or regulated information.
How can I find ISSO jobs paying $100,000 or more?
Browse Information Systems Security Officer listings on Ladders and review each posting’s compensation, qualifications, location, and clearance requirements to find roles that fit your experience.