Information Systems Security Officers help organizations protect sensitive data, systems, and networks. ISSOs assess security risks, guide teams through compliance requirements, and help ensure that information systems are designed and operated securely. Explore vetted ISSO opportunities on Ladders, including professional roles that pay $100,000 or more.
Responsibilities vary by employer and industry, but ISSOs commonly maintain security documentation, monitor system controls, coordinate risk assessments, and support authorization and compliance activities. They may work with system owners, security engineers, auditors, and government stakeholders to identify vulnerabilities and address findings.
Employers often seek experience in information security, risk management, security controls, and regulatory or government frameworks. Familiarity with standards such as NIST guidance, authorization processes, incident response, and security assessment practices can be valuable. Some roles require a bachelor’s degree, relevant certifications, security clearance, or experience supporting federal systems; requirements differ by position.
ISSO professionals work across government contracting, defense, technology, healthcare, financial services, and other sectors with complex security needs. Depending on experience, they may advance into senior ISSO, information assurance, cybersecurity program management, or security leadership roles. Browse current listings to compare responsibilities, qualifications, work arrangements, and compensation.
Use Ladders to explore vetted professional opportunities, including Information Systems Security Officer jobs with salaries of $100,000 or more. Review each listing for its specific pay range, location, clearance requirements, and experience expectations, then apply to roles aligned with your background.
$120K - $145K *
Lead a team of network engineers to design, implement, and secure cloud and hybrid network infrastructures, ensuring reliability and scalability while mentoring staff and driving process improvements...
2 weeks ago
$110K - $130K *
Lead and inspire a skilled agile team focused on the ServiceNow Platform, ensuring efficient delivery of enterprise service management solutions while collaborating with stakeholders to prioritize and...
2 weeks ago
Enterprise Active Directory & Email Services Lead
$120K - $145K *
Unlock your potential as a technical leader driving enterprise identity and messaging services. Manage a talented team of engineers, ensuring reliable operations and security in a hybrid environment w...
3 weeks ago
$89K - $131K *
Join a team that's dedicated to optimizing Epic applications across clinical and revenue cycle areas. Collaborate with stakeholders to enhance workflows, system performance, and user experience while...
1 week ago
$83K - $154K *
Join our team to oversee supplier activities, ensuring compliance with nuclear quality standards through effective monitoring, inspection, and evaluation. Contribute to project success by identifying...
Today
Project / Product Manager - Remote
$120K - $150K *
Shape the future of specialized federal projects by managing product delivery from inception to completion, ensuring alignment with organizational goals, budgets, and schedules while leading cross-fun...
3 weeks ago
$110K - $130K *
Join a team that's driving high-impact commercial data center projects from inception to completion, ensuring alignment with strategic goals, timelines, and budgets while fostering collaboration among...
Yesterday
$110K - $130K *
Lead the charge in managing high-impact commercial data center projects, ensuring alignment with client goals, timelines, and budgets while fostering collaboration among stakeholders and driving opera...
Yesterday
Sr. Director, Information Security
$220K - $250K *
Lead enterprise security operations and resilience, driving cyber risk strategy and innovation. Collaborate cross-functionally to embed security principles, modernize defenses, and build high-performi...
6 days ago
Vulnerability Management Analyst
$121K - $152K *
Champion the vulnerability management program by overseeing project execution, ensuring compliance with security standards, and collaborating with IT teams to enhance system security and mitigate risk...
1 week ago
Sales & Product Enablement Manager (US, Remote)
$100K - $120K *
Join a dynamic team to develop and implement sales enablement strategies that empower customer-facing teams with essential product knowledge and training, driving organizational success and enhancing...
Yesterday
$80K - $90K *
Empower data-driven decision-making by developing and enhancing Power BI dashboards and reports. Collaborate with cross-functional teams to create user-friendly solutions that consolidate data from mu...
4 days ago
$91K - $163K *
Take ownership of large-scale, cross-functional projects, driving alignment and execution across teams. Influence strategic decisions while managing risks and ensuring operational excellence to delive...
Today
CS Business Systems Analyst III
$83K - $145K *
Transform client operations by delivering innovative business systems solutions. Collaborate with stakeholders to integrate technology and processes, ensuring timely service and continuous improvement...
Yesterday
Google Cloud & Gemini Enterprise Administrator
$110K - $130K *
Champion the administration of Google Cloud and Gemini Enterprise environments, ensuring secure, scalable configurations. Collaborate with IT and business teams to optimize cloud services and support...
2 weeks ago
Sr. Strategic Alliance Manager
$150K - $225K *
Engage with us to drive strategic alliances, enhance partnerships, and execute joint initiatives that foster revenue growth and market presence. Collaborate across teams to position solutions effectiv...
1 week ago
$135K - $160K *
Champion innovative solutions by advising top financial institutions on identity verification and fraud prevention. Collaborate cross-functionally to ensure seamless client experiences and drive produ...
4 days ago
Mid-Level Grid Interconnection Consultant
$84K - $129K *
Grow your career with impactful utility consulting projects that involve advanced power system studies, interconnection applications, and guiding clients in renewable energy integration while collabor...
4 weeks ago
Principal Customer Success Manager ( Armis/Veza)
$133K - $233K *
Optimize customer success through engagement & technical leadership, ensuring value from platform utilization. Collaborate across teams to align strategic goals and facilitate adoption, driving except...
3 weeks ago
$110K - $130K *
Engage in strategic project management to drive transformation and enhance customer experience across a portfolio. You'll oversee resource allocation, stakeholder communication, and successful project...
3 weeks ago
Senior Solutions IT Architect supporting Capacity Growth-Remote, Domestic US Locations
$132K - $251K *
Unlock potential by leading technical design for resilient architectures that enhance classified system capabilities, aligning IT solutions with business objectives while collaborating with senior eng...
Reposted 3 weeks ago
$87K - $119K *
Transform the landscape of fraud detection by leading a skilled SIU team. Oversee investigations, collaborate with law enforcement, and ensure compliance while mentoring staff to uphold integrity in h...
4 days ago
$110K - $130K *
Shape the future of customer success by providing technical guidance and innovative solutions. Act as a trusted advisor, ensuring clients maximize product value while managing complex issues and advoc...
1 week ago
$120K - $145K *
Lead the design and implementation of robust security measures to protect sensitive health information, ensuring compliance with HIPAA and other regulations while collaborating with cross-functional t...
3 weeks ago
$100K - $120K *
Lead the charge in managing IT infrastructure and systems while mentoring a dedicated team. Drive cybersecurity initiatives, oversee technology planning, and ensure seamless end-user support to enhanc...
3 weeks ago
What is an Information Systems Security Officer (ISSO)?
An ISSO is a cybersecurity professional who helps protect an organization’s information systems by coordinating security controls, assessing risks, maintaining documentation, and supporting compliance and authorization activities.
What qualifications are commonly required for ISSO jobs?
Requirements vary, but employers commonly look for information security or IT experience, knowledge of security controls and risk management, and familiarity with relevant standards such as NIST guidance. Some positions may require a degree, professional certifications, or an active security clearance.
How much do Information Systems Security Officers earn?
Compensation varies by employer, location, experience, clearance, and job scope. Ladders focuses on vetted professional jobs paying $100,000 or more; check each listing for its stated salary or compensation details.
Where do ISSOs work?
ISSO roles are found in government and defense contracting, technology, healthcare, financial services, and other industries that manage sensitive or regulated information.
How can I find ISSO jobs paying $100,000 or more?
Browse Information Systems Security Officer listings on Ladders and review each posting’s compensation, qualifications, location, and clearance requirements to find roles that fit your experience.