Welcome to Information Systems Security Officer (ISSO) Jobs

As an Information Systems Security Officer (ISSO), you play a critical role in protecting an organization's information system. Discover opportunities that pay over $100k, exclusively available on Ladders.

Job responsibilities

As an ISSO, your responsibilities can include ensuring system security, conducting regular checks, and implementing the organization's security policy.

Skills Needed

Successful ISSOs often have strong technical abilities, knowledge of IT security, problem-solving skills, and an understanding of relevant laws and regulations.

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1
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$135K - $150K *

Unlock potential by leading application security initiatives, conducting testing, and enhancing secure coding practices across teams, ensuring resilient applications throughout development and product...

US-AnywhereRemote

1 week ago

  •   5 - 7 years exp.  •   Information Technology

$100K - $120K *

Unlock potential by leading coding operations across specialties, analyzing performance, and ensuring quality in professional and outpatient coding. Drive strategic goals and enhance departmental effe...

US-AnywhereRemote

Reposted 3 days ago

  •   5 - 7 years exp.  •   Healthcare

$100K - $130K *

Drive secure development practices by conducting assessments, reviews, and integrations for enterprise applications supporting federal missions, ensuring compliance with stringent security standards...

US-AnywhereRemote

Reposted 3 weeks ago

  •   5 - 7 years exp.  •   Aerospace & Defense

$110K - $120K *

Innovate operational reliability by joining our engineering team as a Site Reliability Engineer, enhancing cloud platform performance, automating processes, and ensuring system availability to provide...

US-AnywhereRemote

2 weeks ago

  •   Less than 5 years exp.  •   Information Technology

$110K - $130K *

Support the operational health and reliability of our cloud platform by leveraging Site Reliability Engineering practices. Engage in proactive incident management, enhance automation, and collaborate...

US-AnywhereRemote

3 weeks ago

  •   Less than 5 years exp.  •   Information Technology

$168K - $183K *

Contribute to secure software development by leading design and implementation efforts, mentoring engineers and addressing complex challenges in client-side applications across multiple platforms incl...

US-AnywhereRemote

Reposted 4 days ago

  •   8 - 10 years exp.  •   Information Technology

$149K - $220K *

Champion transformative partnerships by empowering teams to deliver cutting-edge cybersecurity solutions. Collaborate across functions to connect technology with business outcomes, ensuring enterprise...

US-AnywhereRemote

6 days ago

  •   5 - 7 years exp.  •   Enterprise Technology

$76K - $126K *

Empower clinical excellence by overseeing OPPE and FPPE processes with a focus on regulatory compliance and provider performance. Collaborate with leadership to enhance privilege management and ensure...

US-AnywhereRemote

3 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$102K - $170K *

Lead the charge in full-stack development, collaborating on enterprise modernization with Microservices. Deliver high-quality software, mentor engineers, and ensure best practices for cloud technologi...

US-AnywhereRemote

4 days ago

  •   5 - 7 years exp.  •   Enterprise Technology

$119K - $202K *

Innovate your career with a dynamic Tier 1 support role specializing in Maximo. Engage directly with users to troubleshoot issues, manage logs, and elevate customer service. Enjoy a fast-paced environ...

US-AnywhereRemote

2 weeks ago

  •   Less than 5 years exp.  •   Information Technology

$111K - $175K *

Drive revenue growth by enhancing strategic customer relationships, increasing retention, and identifying expansion opportunities through collaborative account management. Influence outcomes and manag...

US-AnywhereRemote

Reposted 4 days ago

  •   5 - 7 years exp.  •   Education, Government & Non-Profit

$75K - $115K *

Lead the charge in GCP auditing to ensure compliance with quality standards and regulations. Conduct complex audits, assess non-conformance issues, and mentor junior auditors. Drive improvements and m...

US-AnywhereRemote

5 days ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$154K - $215K *

Lead and innovate the enterprise WAN and SD-WAN architecture, driving strategic design and enhancements across diverse environments to ensure resilient, scalable network solutions that support critica...

US-AnywhereRemote

Reposted 5 days ago

  •   Less than 5 years exp.  •   Information Technology

$80K - $145K *

Advance high-impact oncology and cell & gene therapy trials as you lead project management efforts, ensuring successful execution from start to finish with strong collaboration between sponsor and CRO...

US-AnywhereRemote

2 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$80K - $145K *

Join a team that drives innovative oncology and cell therapy trials. Leverage your project management skills to oversee complex studies, ensuring compliance and stakeholder collaboration, while foster...

US-AnywhereRemote

2 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$134K - $192K *

Transform administrative tasks through innovative automation scripts using PowerShell, Azure CLI, and Ansible, while securing Azure databases and optimizing cloud infrastructure for peak performance a...

US-AnywhereRemote

3 weeks ago

  •   Less than 5 years exp.  •   Information Technology

$180K - $240K *

Join a team that's redefining national security tech by developing AI-enabled solutions. Collaborate closely with federal clients to build production-ready systems that solve complex mission challenge...

US-AnywhereRemote

4 weeks ago

  •   Less than 5 years exp.  •   Aerospace & Defense

$72K - $115K *

Drive the optimization of provider reimbursement strategies through data analysis and financial modeling, leveraging advanced tools and analytics to enhance accuracy and efficiency across healthcare c...

US-AnywhereRemote

Reposted 1 week ago

  •   Less than 5 years exp.  •   Healthcare

$126K - $188K *

Shape the future of security operations by leading SOC Engineering to enhance telemetry, detection, and automation capabilities. Drive technical excellence, scalability, and strategic initiatives whil...

US-AnywhereRemote

2 weeks ago

  •   8 - 10 years exp.  •   Information Technology

$148K - $266K *

Engage as a Senior Vulnerability Research/Reverse Engineer, leading critical R&D efforts in military cyber operations, focusing on discovering and mitigating vulnerabilities in diverse systems to supp...

US-AnywhereRemote

1 week ago

  •   8 - 10 years exp.  •   Aerospace & Defense

$148K - $266K *

Discover innovative solutions as you lead vulnerability research and cyber tool development. Join a mission-driven team dedicated to enhancing military cyber operations and national defense objectives...

US-AnywhereRemote

2 weeks ago

  •   8 - 10 years exp.  •   Information Technology

$95K - $115K *

Lead advanced cost analysis and pricing strategies for federal acquisitions. Support acquisition teams with expert insights on cost proposals, compliance, and market trends to drive effective decision...

US-AnywhereRemote

5 days ago

  •   5 - 7 years exp.  •   Aerospace & Defense

$84K - $141K *

Engage in the support and optimization of SCADA systems for electric grid monitoring and control. Develop and evaluate engineering solutions to enhance system performance while ensuring seamless opera...

US-AnywhereRemote

Reposted 2 weeks ago

  •   Less than 5 years exp.  •   Energy & Utilities

$135K - $178K *

Define and execute the security strategy for AI technologies and Azure cloud, driving innovations in secure system design, governance, and threat modeling while influencing best practices across enter...

US-AnywhereRemote

3 weeks ago

  •   8 - 10 years exp.  •   Information Technology

$120K - $160K *

Accelerate procurement excellence by leading diverse teams to streamline complex material management, ensuring timely and compliant supplier performance while driving strategic relationships to meet o...

US-AnywhereRemote

Reposted 4 days ago

  •   11 - 15 years exp.  •   Education, Government & Non-Profit

Frequently Asked Questions (FAQ)

  • What is the role of an Information Systems Security Officer (ISSO)?question toggle

    An ISSO is responsible for ensuring the confidentiality and integrity of an organization's information system. They implement the organization's IT security policies and conduct regular checks and audits.

  • What skills do you need for ISSO jobs?question toggle

    ISSOs need strong technical abilities, knowledge of IT security, problem-solving skills, and an understanding of relevant laws and regulations.

  • What kind of ISSO jobs are available on Ladders?question toggle

    Ladders offers a variety of high-paying ISSO jobs from reputable companies that value your skills and experience.