Information Systems Security Officer (ISSO) Jobs

Information Systems Security Officers help organizations protect sensitive data, systems, and networks. ISSOs assess security risks, guide teams through compliance requirements, and help ensure that information systems are designed and operated securely. Explore vetted ISSO opportunities on Ladders, including professional roles that pay $100,000 or more.

What Does an ISSO Do?

Responsibilities vary by employer and industry, but ISSOs commonly maintain security documentation, monitor system controls, coordinate risk assessments, and support authorization and compliance activities. They may work with system owners, security engineers, auditors, and government stakeholders to identify vulnerabilities and address findings.

Common ISSO Skills and Qualifications

Employers often seek experience in information security, risk management, security controls, and regulatory or government frameworks. Familiarity with standards such as NIST guidance, authorization processes, incident response, and security assessment practices can be valuable. Some roles require a bachelor’s degree, relevant certifications, security clearance, or experience supporting federal systems; requirements differ by position.

ISSO Career Opportunities

ISSO professionals work across government contracting, defense, technology, healthcare, financial services, and other sectors with complex security needs. Depending on experience, they may advance into senior ISSO, information assurance, cybersecurity program management, or security leadership roles. Browse current listings to compare responsibilities, qualifications, work arrangements, and compensation.

Find ISSO Jobs on Ladders

Use Ladders to explore vetted professional opportunities, including Information Systems Security Officer jobs with salaries of $100,000 or more. Review each listing for its specific pay range, location, clearance requirements, and experience expectations, then apply to roles aligned with your background.

Remote
caret down
Compensation
caret down
Position Level
caret down
Time Posted
caret down
Industries
caret down
More
1
caret down

$120K - $230K *

Lead consultative engagements as a network expert, collaborating with account teams to design tailored solutions that align with customer objectives and drive business growth. Strengthen partnerships...

California, USRemote

3 days ago

  •   Less than 5 years exp.  •   Technical Services

$81K - $138K *

Drive innovative Salesforce solutions by designing, developing, and integrating applications. Collaborate with cross-functional teams to enhance user experiences and ensure compliance with federal sta...

Reston, VARemote

1 week ago

  •   Less than 5 years exp.  •   Business Services

$79K - $103K *

Manage and optimize enterprise middleware platforms, driving performance and support for IBM solutions. Collaborate with teams to implement best practices and troubleshoot issues in high availability...

Florham Park, NJRemote

3 weeks ago

  •   8 - 10 years exp.  •   Business Services

$88K - $154K *

Optimize document management processes for a large-scale industrial project, ensuring accurate, secure, and accessible records throughout all project phases. Collaborate with multidisciplinary teams t...

United StatesRemote

Today

  •   8 - 10 years exp.  •   Real Estate & Construction

$120K - $145K *

Champion innovative technology solutions as a lead architect and advisor, collaborating with stakeholders to address complex business challenges and drive impactful outcomes through strategic planning...

RemoteRemote

3 weeks ago

  •   5 - 7 years exp.  •   Hospitals & Medical Centers

$70K - $114K *

Transform your career by overseeing OSP construction projects across multiple locations. Collaborate with diverse teams to ensure compliance, manage budgets, and drive successful implementation of fib...

Beaver Dam, WIRemote

Yesterday

  •   Less than 5 years exp.  •   Technical Services

$120K - $140K *

Elevate client success by leading MSP program implementations from discovery to launch. Collaborate with cross-functional teams to ensure alignment with client objectives, manage risks, and drive proj...

Pennsylvania, USRemote

1 week ago

  •   Less than 5 years exp.  •   Information Technology

$131K - $243K *

Lead the charge in managing industrial development initiatives, ensuring compliance with international regulations while fostering relationships with global partners. Oversee program implementation, b...

Florida, USRemote

2 weeks ago

  •   5 - 7 years exp.  •   Aerospace & Defense

$86K - $138K *

Unlock potential by leveraging AI tools to produce high-quality analytical insights. Collaborate with diverse teams to enhance workflows and drive mission success through innovative data analysis and...

United StatesRemote

Yesterday

  •   5 - 7 years exp.  •   Aerospace & Defense

$135K - $216K *

Join a team that's driving growth initiatives for the US Air Force. You'll develop strategies, manage relationships, and support pipeline development to enhance business opportunities and position the...

Mc Lean, VARemote

2 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$91K - $163K *

Empower your career by driving innovative software solutions through end-to-end development, collaborating with Agile teams, and leveraging cutting-edge technologies to enhance product quality and eff...

Eden Prairie, MNRemote

Yesterday

  •   8 - 10 years exp.  •   Healthcare

$161K - $218K *

Drive the successful migration from Microsoft Azure to Oracle Cloud Infrastructure, overseeing planning, execution, and governance. Collaborate with cross-functional teams to minimize disruption and m...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Information Technology

$75K - $158K *

Join a dynamic team to ensure the quality and compliance of Oracle HCM systems across federal agencies. Design and execute test strategies, automate testing processes, and validate integrations, ensur...

RemoteRemote

Reposted 1 week ago

  •   5 - 7 years exp.  •   Information Technology

$90K - $189K *

Advance your career by ensuring quality and compliance for a federal HCM platform. Design and execute test strategies, manage automated testing, and validate performance within a SAFe Agile framework...

RemoteRemote

Reposted 1 week ago

  •   5 - 7 years exp.  •   Information Technology

$110K - $130K *

Architect solutions to enhance DevOps teams' security by managing pre-sales technical support, conducting product demos, and serving as a subject matter expert in CI/CD integrations and workflows. Eng...

United StatesRemote

Reposted 3 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$199K - $270K *

Tackle the complexities of backend engineering by developing robust API integrations, building ETL pipelines, and collaborating with cross-functional teams to enhance system reliability and performanc...

United StatesRemote

Reposted 4 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$110K - $135K *

Drive growth by partnering with sales teams to identify and develop cybersecurity service opportunities. Lead consultative engagements, create proposals, and deliver impactful presentations while coll...

New York, NYRemote

Reposted 1 week ago

  •   5 - 7 years exp.  •   Information Technology

$100K - $160K *

Unlock potential by developing and enhancing Java applications for a large-scale IAM platform. Collaborate with experts to design solutions, troubleshoot issues, and ensure system stability in a dynam...

United StatesRemote

2 days ago

  •   5 - 7 years exp.  •   Enterprise Technology

$111K - $206K *

Lead cross-functional teams to develop and manage integrated program schedules, ensuring effective execution and performance through Earned Value Management and critical path analysis. Drive collabora...

Fort Worth, TXRemote

4 days ago

  •   8 - 10 years exp.  •   Aerospace & Defense

$155K - $185K *

Pioneer effective supply chain management by coordinating program activities, ensuring timely material deliverables, and consolidating data for decision-making across cross-functional teams to meet pe...

Lorton, VARemote

4 days ago

  •   5 - 7 years exp.  •   Aerospace & Defense

$125K - $140K *

Transform proposal writing by crafting compelling narratives that align with solicitation requirements. Collaborate with technical experts to translate complex solutions into clear, persuasive content...

Herndon, VARemote

2 weeks ago

  •   5 - 7 years exp.  •   Business Services

$80K - $95K *

Drive your career by providing advanced technical support, optimizing software systems, and implementing innovative solutions in a dynamic, 100% remote environment. Collaborate to enhance operational...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Enterprise Technology

$150K - $225K *

Join a team that's dedicated to ensuring 24/7 operations of critical data centers. Lead engineering and operations teams to optimize infrastructure, enhance reliability, and modernize systems, all whi...

Rockville, MDRemote

1 week ago

  •   8 - 10 years exp.  •   Information Technology

$175K - $200K *

Take ownership of transformative security solutions by leading complex client engagements in vulnerability management and exposure assessment. Drive risk-based strategies and architect innovative prog...

Dallas, TXRemote

Today

  •   8 - 10 years exp.  •   Information Technology

$110K - $130K *

Transform legacy systems into modern applications, leveraging your expertise in IBMi and collaborating with international teams to meet diverse client needs. Drive innovation and excellence in system...

Chicago, ILRemote

3 weeks ago

  •   Less than 5 years exp.  •   Information Technology

Frequently Asked Questions (FAQ)

  • What is an Information Systems Security Officer (ISSO)?question toggle

    An ISSO is a cybersecurity professional who helps protect an organization’s information systems by coordinating security controls, assessing risks, maintaining documentation, and supporting compliance and authorization activities.

  • What qualifications are commonly required for ISSO jobs?question toggle

    Requirements vary, but employers commonly look for information security or IT experience, knowledge of security controls and risk management, and familiarity with relevant standards such as NIST guidance. Some positions may require a degree, professional certifications, or an active security clearance.

  • How much do Information Systems Security Officers earn?question toggle

    Compensation varies by employer, location, experience, clearance, and job scope. Ladders focuses on vetted professional jobs paying $100,000 or more; check each listing for its stated salary or compensation details.

  • Where do ISSOs work?question toggle

    ISSO roles are found in government and defense contracting, technology, healthcare, financial services, and other industries that manage sensitive or regulated information.

  • How can I find ISSO jobs paying $100,000 or more?question toggle

    Browse Information Systems Security Officer listings on Ladders and review each posting’s compensation, qualifications, location, and clearance requirements to find roles that fit your experience.