Welcome to Information Systems Security Officer (ISSO) Jobs

As an Information Systems Security Officer (ISSO), you play a critical role in protecting an organization's information system. Discover opportunities that pay over $100k, exclusively available on Ladders.

Job responsibilities

As an ISSO, your responsibilities can include ensuring system security, conducting regular checks, and implementing the organization's security policy.

Skills Needed

Successful ISSOs often have strong technical abilities, knowledge of IT security, problem-solving skills, and an understanding of relevant laws and regulations.

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Compensation
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Position Level
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$184K - $253K *

Empower teams by owning the architecture of a self-hosted platform, ensuring high availability and scalability while mentoring engineers and influencing the product roadmap across diverse environments...

US-AnywhereRemote

2 weeks ago

  •   8 - 10 years exp.  •   Enterprise Technology

$90K - $120K *

Elevate training excellence by delivering advanced technical training for clinical research. Foster client alignment and support diverse training needs through innovative methods and collaboration, dr...

US-AnywhereRemote

2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$115K - $125K *

Accelerate sales growth by driving partner enablement and enhancing market strategies within the Central and Western territories, focusing on mission-critical video and software solutions for governme...

US-AnywhereRemote

1 week ago

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$80K - $90K *

Empower your career by leading the management of federal acquisitions, overseeing complex contracts, ensuring compliance, and guiding stakeholders in a strategic role that shapes the future of procure...

US-AnywhereRemote

4 weeks ago

  •   5 - 7 years exp.  •   Education, Government & Non-Profit

$80K - $90K *

Advance federal acquisition strategies by overseeing complex contracting processes. Utilize your expertise to ensure compliance, guide stakeholders, and mentor junior staff in all stages of contract l...

US-AnywhereRemote

4 weeks ago

  •   5 - 7 years exp.  •   Education, Government & Non-Profit

$120K - $150K *

Drive innovation in DevSecOps by leveraging your expertise in Kubernetes, Terraform, and CI/CD to enhance the Platform One initiative for the US Air Force, ensuring compliance with cybersecurity stand...

US-AnywhereRemote

3 weeks ago

  •   Less than 5 years exp.  •   Aerospace & Defense

$105K - $130K *

Join us to optimize and support critical pharmaceutical applications such as Veeva Vault and CRM. Collaborate with cross-functional teams to improve operations, enhance system functionality, and ensur...

US-AnywhereRemote

1 week ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$75K - $95K *

Contribute to improving clinical documentation integrity through developing standard processes, educating staff, and conducting thorough reviews to enhance compliance and support value-based care init...

US-AnywhereRemote

3 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$120K - $150K *

Unlock your potential by leading a dynamic team focused on operational risk management, ensuring safe delivery of new capacity. Drive cross-functional collaboration and continuous improvement to enhan...

US-AnywhereRemote

1 week ago

  •   8 - 10 years exp.  •   Technical Services

$75K - $105K *

Drive operational excellence by automating CI/CD pipelines and improving infrastructure stability across diverse applications, ensuring secure and efficient deployment in agile environments. Take owne...

US-AnywhereRemote

2 weeks ago

  •   Less than 5 years exp.  •   Information Technology

$131K - $210K *

Drive proactive security compliance as a hands-on leader, mentoring a GRC team while executing high-impact projects. Ensure audit readiness through innovative design, engineering partnerships, and con...

US-AnywhereRemote

Reposted 1 week ago

  •   5 - 7 years exp.  •   Information Technology

$100K - $175K *

Grow expertise in Operational Technology security, leading critical engagements across industrial systems. Collaborate on advanced methodologies while mentoring others and contributing to pivotal rese...

US-AnywhereRemote

1 week ago

  •   5 - 7 years exp.  •   Energy & Utilities

$90K - $120K *

Transform the coding and CDI landscape by leading audit and education initiatives, ensuring compliance and enhancing performance across teams. Drive training development and process improvement to fos...

US-AnywhereRemote

4 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$110K - $150K *

Shape the future of cybersecurity by designing cutting-edge PKI architecture that supports robust authentication and Zero Trust initiatives while collaborating with cross-functional teams to ensure op...

US-AnywhereRemote

1 week ago

  •   Less than 5 years exp.  •   Information Technology

$100K - $130K *

Transform the future of technology services by leading seamless contract transitions while coordinating with IT partners and ensuring optimal performance across public-sector contracts in a complex en...

US-AnywhereRemote

3 weeks ago

  •   8 - 10 years exp.  •   Enterprise Technology

$105K - $120K *

Innovate modern DevOps practices to enhance software delivery, streamline CI/CD pipelines, and automate environment management. Collaborate with engineering to drive efficiency, reliability, and conti...

US-AnywhereRemote

3 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$90K - $120K *

Contribute to growth in Managed Services and Smart Platforms by driving adoption of AI-enabled offerings, influencing account strategy, and enhancing customer relationships through strategic sales ini...

US-AnywhereRemote

1 week ago

  •   5 - 7 years exp.  •   Technical Services

$140K - $215K *

Shape the future of endpoint security by engineering critical detection and response functionalities for a leading security platform, collaborating across teams while enhancing complex system capabili...

US-AnywhereRemote

4 weeks ago

  •   Less than 5 years exp.  •   Information Technology

$80K - $120K *

Lead the charge in fortifying critical infrastructure by safeguarding OT/ICS systems from cyber threats while collaborating with engineering teams to ensure secure and uninterrupted operations in dyna...

US-AnywhereRemote

2 weeks ago

  •   Less than 5 years exp.  •   Energy & Utilities

$153K - $275K *

Contribute to the development and execution of go-to-market strategies, conducting market research, and collaborating cross-functionally to bridge technology offerings with government and military nee...

US-AnywhereRemote

6 days ago

  •   11 - 15 years exp.  •   Aerospace & Defense

$130K - $160K *

Architect a comprehensive integration strategy, overseeing the design and governance of enterprise-wide data transfers and API frameworks to ensure secure, scalable, and reliable connectivity across a...

Reposted 2 weeks ago

  •   8 - 10 years exp.  •   Enterprise Technology

$120K - $150K *

Join a team that's leading the data migration from various ERPs to SAP S/4HANA. Drive high-quality data integration, ensuring business continuity and success in go-live with a focus on master data obj...

US-AnywhereRemote

3 days ago

  •   Less than 5 years exp.  •   Enterprise Technology

$90K - $120K *

Join a team that's enhancing systems through expert analysis, functional testing, and innovative solutions. Your role involves collaborating with business partners, developing requirements, and optimi...

US-AnywhereRemote

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$69K - $93K *

Champion outbound prospecting by qualifying leads in the government sector. Drive engagement with key decision-makers through compelling messaging, collaboration, and strategic outreach to build a rob...

US-AnywhereRemote

2 weeks ago

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$80K - $110K *

Drive assurance and validation processes for computerized systems in cGMP environments. Collaborate with cross-functional teams, ensuring compliance and excellence in testing and documentation to enha...

US-AnywhereRemote

2 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

Frequently Asked Questions (FAQ)

  • What is the role of an Information Systems Security Officer (ISSO)?question toggle

    An ISSO is responsible for ensuring the confidentiality and integrity of an organization's information system. They implement the organization's IT security policies and conduct regular checks and audits.

  • What skills do you need for ISSO jobs?question toggle

    ISSOs need strong technical abilities, knowledge of IT security, problem-solving skills, and an understanding of relevant laws and regulations.

  • What kind of ISSO jobs are available on Ladders?question toggle

    Ladders offers a variety of high-paying ISSO jobs from reputable companies that value your skills and experience.