Information Systems Security Officers help organizations protect sensitive data, systems, and networks. ISSOs assess security risks, guide teams through compliance requirements, and help ensure that information systems are designed and operated securely. Explore vetted ISSO opportunities on Ladders, including professional roles that pay $100,000 or more.
Responsibilities vary by employer and industry, but ISSOs commonly maintain security documentation, monitor system controls, coordinate risk assessments, and support authorization and compliance activities. They may work with system owners, security engineers, auditors, and government stakeholders to identify vulnerabilities and address findings.
Employers often seek experience in information security, risk management, security controls, and regulatory or government frameworks. Familiarity with standards such as NIST guidance, authorization processes, incident response, and security assessment practices can be valuable. Some roles require a bachelor’s degree, relevant certifications, security clearance, or experience supporting federal systems; requirements differ by position.
ISSO professionals work across government contracting, defense, technology, healthcare, financial services, and other sectors with complex security needs. Depending on experience, they may advance into senior ISSO, information assurance, cybersecurity program management, or security leadership roles. Browse current listings to compare responsibilities, qualifications, work arrangements, and compensation.
Use Ladders to explore vetted professional opportunities, including Information Systems Security Officer jobs with salaries of $100,000 or more. Review each listing for its specific pay range, location, clearance requirements, and experience expectations, then apply to roles aligned with your background.
$110K - $130K *
Engage with sales teams to identify prospects and demonstrate solutions that enhance organizational security. Educate clients on challenges and drive meetings to provide tailored solutions, ensuring e...
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Senior HCM Analytics & BI Developer
$105K - $231K *
Optimize enterprise analytics solutions to provide real-time insights and reporting for federal HR stakeholders, driving strategic decision-making and compliance in a fast-paced modernization initiati...
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$82K - $172K *
Transform complex data ecosystems by leveraging your Elasticsearch expertise to design, optimize, and lead advanced analytics initiatives. Collaborate with cross-functional teams to enhance mission-cr...
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$120K - $130K *
Lead the charge in managing a dynamic OS Administrator team, ensuring seamless RHEL and Windows OS patching in a 24/7 environment while leveraging automation tools and collaborating with cross-functio...
1 week ago
Staff Customer Support Programs & Supportability Lead
$154K - $180K *
Unlock your potential as a strategic leader driving customer support excellence. Own high-impact programs, optimize processes, and collaborate with cross-functional teams to enhance customer experienc...
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Unlock AI-driven engineering transformation by collaborating with clients to enhance SDLC processes. Drive measurable improvements in delivery speed and quality through innovative solutions and hands...
1 week ago
Manager, Forward Deployed Services - Remote
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Lead the charge in managing complex client relationships while guiding a team through the full post-sales lifecycle. Drive product design, implementation, and client success in a hands-on, player-coac...
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$100K - $125K *
Join us to lead audit engagements for governmental and nonprofit clients, mentor emerging auditors, and solve complex accounting challenges while delivering exceptional client service in a fully remot...
1 week ago
(USA) Senior Manager, Global IT SOX
$90K - $180K *
Unlock the potential of IT compliance by leading SOX activities, ensuring effective controls, and fostering collaboration across teams to enhance financial reporting integrity and operational excellen...
5 days ago
$86K - $138K *
Join us to lead the installation and support of next-gen Voice Communication Switch systems. This role demands technical expertise and customer interaction to ensure seamless transitions and operation...
2 weeks ago
IT Technical Training Lead (Senior)
$110K - $130K *
Lead the development and execution of technical training programs, ensuring alignment with enterprise modernization and operational priorities. Collaborate with stakeholders to enhance workforce profi...
2 days ago
Senior Solutions Engineer, MSSP Ecosystem Partner
$196K - $270K *
Join a team that's driving innovation in the MSSP ecosystem. Lead technical strategy, engage with partners, and shape the future of security solutions across North America while fostering deep relatio...
1 week ago
$80K - $95K *
Drive the success of a 24/7 NOC team by mentoring agents, overseeing infrastructure monitoring, and ensuring effective incident management while fostering a collaborative environment focused on contin...
1 week ago
$180K - $250K *
Lead the charge in our cybersecurity operations, overseeing teams and strategies to enhance effective security monitoring and incident response while ensuring top-notch service delivery across diverse...
Reposted 1 week ago
$100K - $120K *
Join a team that's shaping the future of secure web applications. Leverage your full-stack development skills to build scalable solutions in a collaborative Agile environment, tackling complex challen...
3 days ago
$46K - $122K *
Lead the charge in implementing health insurance projects by collaborating with teams, analyzing client needs, and ensuring successful onboarding. Foster relationships and provide mentorship to drive...
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Client Delivery Manager - Revenue Cycle (REMOTE)
$80K - $95K *
Champion operational excellence by managing client accounts, translating performance data into actionable insights, and fostering strong relationships to align expectations with capabilities. Drive co...
4 days ago
$170K - $201K *
Join us to lead the charge in cybersecurity as a Network Engineer Expert, ensuring robust enterprise network security solutions. Collaborate with teams to tackle complex challenges and drive innovatio...
1 week ago
$140K - $150K *
Unlock potential by shaping the future of Azure DevSecOps. Engage in platform engineering, operational support, and compliance management while collaborating across teams to enhance systems and delive...
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$110K - $130K *
Elevate your career by leading complex enterprise projects, driving change, and optimizing client relationships. Collaborate across teams to identify opportunities and enhance project management proce...
1 week ago
Sr. Practice Manager -- AI Agentic Ops
$150K - $190K *
Help us shape the future of AI operations by leading a dynamic team focused on innovative solutions, strategic partnerships, and technical excellence in agentic environments. Drive growth and operatio...
2 days ago
Staff Security Governance Engineer, Policies & Standards
$168K - $238K *
Optimize security governance and policy management by leveraging automation and AI. Collaborate with cross-functional teams to ensure compliance with emerging regulations and enhance policy effectiven...
Reposted 2 weeks ago
Field Sales Support Systems Engineer - E2
$88K - $163K *
Join a team that provides expert technical support for F-16 electrical systems, coordinates repair activities, and delivers innovative solutions to meet customer needs through collaboration and analys...
3 weeks ago
Senior NetSuite Business Systems Analyst
$130K - $150K *
Contribute to the optimization of our NetSuite ERP platform by leveraging your expertise in system integrations and customizations. Collaborate with cross-functional teams to enhance processes and dri...
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Systems Engineering Lead/Manager - KSA C4I
$161K - $299K *
Transform the future of C4I systems as a Systems Engineering Manager, leading design initiatives and managing a team to ensure alignment with customer requirements. Drive modernization efforts through...
1 week ago
What is an Information Systems Security Officer (ISSO)?
An ISSO is a cybersecurity professional who helps protect an organization’s information systems by coordinating security controls, assessing risks, maintaining documentation, and supporting compliance and authorization activities.
What qualifications are commonly required for ISSO jobs?
Requirements vary, but employers commonly look for information security or IT experience, knowledge of security controls and risk management, and familiarity with relevant standards such as NIST guidance. Some positions may require a degree, professional certifications, or an active security clearance.
How much do Information Systems Security Officers earn?
Compensation varies by employer, location, experience, clearance, and job scope. Ladders focuses on vetted professional jobs paying $100,000 or more; check each listing for its stated salary or compensation details.
Where do ISSOs work?
ISSO roles are found in government and defense contracting, technology, healthcare, financial services, and other industries that manage sensitive or regulated information.
How can I find ISSO jobs paying $100,000 or more?
Browse Information Systems Security Officer listings on Ladders and review each posting’s compensation, qualifications, location, and clearance requirements to find roles that fit your experience.