Information Systems Security Officer (ISSO) Jobs

Information Systems Security Officers help organizations protect sensitive data, systems, and networks. ISSOs assess security risks, guide teams through compliance requirements, and help ensure that information systems are designed and operated securely. Explore vetted ISSO opportunities on Ladders, including professional roles that pay $100,000 or more.

What Does an ISSO Do?

Responsibilities vary by employer and industry, but ISSOs commonly maintain security documentation, monitor system controls, coordinate risk assessments, and support authorization and compliance activities. They may work with system owners, security engineers, auditors, and government stakeholders to identify vulnerabilities and address findings.

Common ISSO Skills and Qualifications

Employers often seek experience in information security, risk management, security controls, and regulatory or government frameworks. Familiarity with standards such as NIST guidance, authorization processes, incident response, and security assessment practices can be valuable. Some roles require a bachelor’s degree, relevant certifications, security clearance, or experience supporting federal systems; requirements differ by position.

ISSO Career Opportunities

ISSO professionals work across government contracting, defense, technology, healthcare, financial services, and other sectors with complex security needs. Depending on experience, they may advance into senior ISSO, information assurance, cybersecurity program management, or security leadership roles. Browse current listings to compare responsibilities, qualifications, work arrangements, and compensation.

Find ISSO Jobs on Ladders

Use Ladders to explore vetted professional opportunities, including Information Systems Security Officer jobs with salaries of $100,000 or more. Review each listing for its specific pay range, location, clearance requirements, and experience expectations, then apply to roles aligned with your background.

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$129K - $212K *

Take ownership of incident response and security monitoring, enhancing processes while mentoring junior team members. Drive investigations and foster collaboration across teams, ensuring member safety...

United StatesRemote

4 weeks ago

  •   Less than 5 years exp.  •   Enterprise Technology

$250K - $350K *

Unlock potential by serving as a strategic advisor to executives, guiding organizations in workplace transformation, technology modernization, and data-driven strategies to enhance productivity and op...

RemoteRemote

1 week ago

  •   8 - 10 years exp.  •   Technical Services

$143K - $205K *

Engage in high-impact enterprise deployments, leading customer projects from kickoff to closure. Collaborate with cross-functional teams to ensure seamless integration of the Zero Trust Exchange platf...

United StatesRemote

4 days ago

  •   5 - 7 years exp.  •   Information Technology

$165K - $231K *

Transform complex security challenges into innovative solutions for public-sector and commercial clients. Lead technical pre-sales efforts, collaborating with sales teams to deliver tailored architect...

United StatesRemote

Yesterday

  •   5 - 7 years exp.  •   Information Technology

$100K - $160K *

Transform operations by coordinating transition and integration activities for sustainment and readiness, ensuring stability while enabling a controlled shift to future models across divisions and sta...

San Diego, CARemote

2 days ago

  •   8 - 10 years exp.  •   Manufacturing & Automotive

$110K - $130K *

Join a team that's transforming legacy systems into modern solutions. As a Senior RPG Programmer/Analyst, you'll lead the design, development, and maintenance of critical IBM i applications, ensuring...

Montreal, QCRemote

3 weeks ago

  •   15+ years exp.  •   Information Technology

$110K - $130K *

Explore a pivotal role in transforming tax compliance into operational confidence. Collaborate with senior Sales Engineers to engage enterprise clients, addressing complex challenges and delivering ta...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Enterprise Technology

$120K - $180K *

Unlock the potential of Army logistics by driving enterprise architecture, cybersecurity, and systems integration initiatives. Collaborate with stakeholders to enhance business processes and deliver i...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Business Services

$92K - $153K *

Drive the design and implementation of security controls in AWS cloud environments, ensuring compliance with security frameworks while collaborating with engineering teams to enhance secure CI/CD proc...

United StatesRemote

Yesterday

  •   5 - 7 years exp.  •   Business Services

$196K - $270K *

Empower the growth of MSSP partnerships by driving adoption, building relationships, and integrating solutions. Collaborate with partners to enhance technical offerings and ensure success through trai...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Enterprise Technology

$225K - $334K *

Transform your career by partnering with us to deliver innovative AI solutions. Leverage your expertise in pre-sales consulting to drive strategic initiatives and enhance customer experiences in the p...

Chicago, ILRemote

2 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$225K - $334K *

Unlock potential by driving AI solutions in the public sector, collaborating with sales teams to deliver tailored demonstrations and strategic insights, while managing customer engagements and ensurin...

Washington, DCRemote

2 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$225K - $334K *

Empower organizations by leveraging AI and cloud solutions to enhance workflows, drive strategic initiatives, and deliver impactful demonstrations that align with customer needs, ensuring successful s...

New York, NYRemote

2 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$225K - $334K *

Unlock potential by joining a dynamic team that drives AI solutions in the public sector. Collaborate with stakeholders, lead workshops, and deliver impactful demonstrations while achieving sales goal...

Boston, MARemote

2 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$110K - $130K *

Engage in transformative DevOps practices by implementing AWS technologies and tooling. Collaborate with product teams to enhance cloud infrastructure, security, and CI/CD pipelines, contributing to a...

United StatesRemote

4 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$104K - $166K *

Drive the integrated risk management and quality framework for IT deployments, ensuring effective risk identification, mitigation, and quality assurance across workstreams while producing insightful d...

United StatesRemote

Today

  •   8 - 10 years exp.  •   Aerospace & Defense

$150K - $180K *

Transform the infrastructure landscape by leading Site Reliability Engineering and platform architecture for global expansion, ensuring reliability, cost efficiency, and compliance across multiple ser...

RemoteRemote

Yesterday

  •   8 - 10 years exp.  •   Healthcare

$105K - $177K *

Elevate your career by mastering Oracle software engineering in a dynamic, remote environment. Collaborate with a skilled team to enhance database performance and support critical applications while d...

United StatesRemote

Reposted 3 days ago

  •   8 - 10 years exp.  •   Information Technology

$150K - $200K *

Join a dynamic team as a trusted advisor, guiding enterprise clients in evaluating, designing, and optimizing their infrastructure environments while leading network transformation initiatives and del...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Business Services

$127K - $160K *

Lead and drive cybersecurity initiatives, managing complex projects and fostering client relationships. Provide strategic guidance and deliver innovative security solutions to enhance organizational r...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Information Technology

$100K - $120K *

Join a team that's redefining client onboarding and implementation in cybersecurity. Drive successful project delivery by translating contracts into actionable plans, coordinating resources, and ensur...

Washington, DCRemote

1 week ago

  •   Less than 5 years exp.  •   Information Technology

$112K - $168K *

Pioneer the evolution of enterprise security operations by optimizing SIEM capabilities, enhancing detection processes, and implementing AI-driven solutions to improve efficiency and response times ac...

Virginia, USRemote

Yesterday

  •   5 - 7 years exp.  •   Finance & Insurance

$120K - $145K *

Drive success at the intersection of leadership and technical delivery, overseeing a team of consultants to ensure optimal service execution and financial performance across U.S. Federal agencies whil...

RemoteRemote

3 weeks ago

  •   5 - 7 years exp.  •   Consumer Technology

$200K - $215K *

Drive innovation in data engineering and AI solutions, leading the design and deployment of scalable systems. Collaborate with cross-functional teams to enhance business value through advanced technol...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Finance & Insurance

$80K - $100K *

Transform complex network systems by leading design, implementation, and support efforts. Collaborate with diverse teams to enhance telecommunications infrastructures and ensure compliance with cybers...

United StatesRemote

3 weeks ago

  •   11 - 15 years exp.  •   Information Technology

Frequently Asked Questions (FAQ)

  • What is an Information Systems Security Officer (ISSO)?question toggle

    An ISSO is a cybersecurity professional who helps protect an organization’s information systems by coordinating security controls, assessing risks, maintaining documentation, and supporting compliance and authorization activities.

  • What qualifications are commonly required for ISSO jobs?question toggle

    Requirements vary, but employers commonly look for information security or IT experience, knowledge of security controls and risk management, and familiarity with relevant standards such as NIST guidance. Some positions may require a degree, professional certifications, or an active security clearance.

  • How much do Information Systems Security Officers earn?question toggle

    Compensation varies by employer, location, experience, clearance, and job scope. Ladders focuses on vetted professional jobs paying $100,000 or more; check each listing for its stated salary or compensation details.

  • Where do ISSOs work?question toggle

    ISSO roles are found in government and defense contracting, technology, healthcare, financial services, and other industries that manage sensitive or regulated information.

  • How can I find ISSO jobs paying $100,000 or more?question toggle

    Browse Information Systems Security Officer listings on Ladders and review each posting’s compensation, qualifications, location, and clearance requirements to find roles that fit your experience.