Information Systems Security Officers help organizations protect sensitive data, systems, and networks. ISSOs assess security risks, guide teams through compliance requirements, and help ensure that information systems are designed and operated securely. Explore vetted ISSO opportunities on Ladders, including professional roles that pay $100,000 or more.
Responsibilities vary by employer and industry, but ISSOs commonly maintain security documentation, monitor system controls, coordinate risk assessments, and support authorization and compliance activities. They may work with system owners, security engineers, auditors, and government stakeholders to identify vulnerabilities and address findings.
Employers often seek experience in information security, risk management, security controls, and regulatory or government frameworks. Familiarity with standards such as NIST guidance, authorization processes, incident response, and security assessment practices can be valuable. Some roles require a bachelor’s degree, relevant certifications, security clearance, or experience supporting federal systems; requirements differ by position.
ISSO professionals work across government contracting, defense, technology, healthcare, financial services, and other sectors with complex security needs. Depending on experience, they may advance into senior ISSO, information assurance, cybersecurity program management, or security leadership roles. Browse current listings to compare responsibilities, qualifications, work arrangements, and compensation.
Use Ladders to explore vetted professional opportunities, including Information Systems Security Officer jobs with salaries of $100,000 or more. Review each listing for its specific pay range, location, clearance requirements, and experience expectations, then apply to roles aligned with your background.
Senior Manager, Security & Compliance
$120K - $145K *
Pioneer our security and compliance program by leading HITRUST certification, managing audits, and enhancing controls. Collaborate with teams to ensure robust security measures while representing the...
2 weeks ago
Sr. Manager Trade Compliance - (100% Remote)
$110K - $130K *
Pioneer in Trade Compliance efforts by utilizing your expertise to navigate regulations, ensuring compliance and efficient operations for defense-related projects. Engage with internal teams while pro...
Reposted yesterday
$110K - $130K *
Shape the future of secure software development by integrating security practices into engineering workflows, building automation tools, and conducting penetration tests to identify vulnerabilities an...
3 days ago
QA Specialist - Service Management Quality (Journeyman)
$80K - $95K *
Join a team that's dedicated to enhancing service quality through rigorous quality assurance and process audits. Collaborate with stakeholders to ensure compliance with ITIL practices and drive contin...
Yesterday
ServiceNow Developer (Journeyman)
$95K - $115K *
Empower your career by configuring and optimizing the ServiceNow platform to enhance IT service management. Collaborate with diverse teams to develop scalable solutions that meet operational needs and...
2 days ago
IT Service Delivery Program Manager, Healthcare
$110K - $130K *
Empower healthcare IT delivery by managing a dynamic team, ensuring operational excellence, and driving EMR performance. Collaborate with clinical stakeholders to enhance patient care through effectiv...
3 days ago
ServiceNow Business Analyst - DOJ FRD
$113K - $188K *
Transform business needs into actionable insights by serving as a Business Analyst for ServiceNow initiatives. Collaborate with stakeholders to enhance platform solutions, streamline processes, and en...
3 days ago
Sr. Manager, Application and Pipeline Security
$120K - $150K *
Elevate your career by leading a dynamic team in transforming cloud and application security. Drive innovative AI-driven DevSecOps strategies while ensuring compliance and fostering collaboration acro...
2 weeks ago
$66K - $110K *
Optimize your career by joining a dynamic team of cyber threat experts. You'll monitor, detect, and respond to security incidents, ensuring robust protection for customer environments while collaborat...
1 week ago
$75K - $158K *
Engage as a key Oracle Application DBA supporting a high-profile multi-agency program. Leverage your experience in Oracle E-Business Suite management to ensure optimal performance and uptime, while en...
Reposted 1 week ago
Mid-level, Full-stack Software Developer
$75K - $158K *
Unlock potential by joining our dynamic team as a mid-level full-stack software developer. Contribute to innovative solutions for the U.S. Navy Reserve, collaborating with experts in an Agile environm...
Reposted 1 week ago
$81K - $93K *
Drive impactful change by supporting federal programs through grants management, analysis, and community engagement. Collaborate with stakeholders to ensure compliance and enhance program effectivenes...
2 weeks ago
Virtual Chief Information Officer (vCIO)
$100K - $120K *
Join a team that's redefining technology strategy for clients. As a strategic advisor, you'll align IT solutions with business goals, lead technology reviews, and optimize investments to drive measura...
2 days ago
$135K - $160K *
Transform product security by leading strategy, conducting threat modeling, and collaborating across teams to ensure secure design and compliance. Drive innovation in security practices while mentorin...
2 weeks ago
Cyber Risk and Compliance Specialist
$95K - $115K *
Unlock potential by leading IT SOX compliance and enhancing global security culture. Balance technical auditing with advocacy, ensuring financial integrity and regulatory adherence while fostering a r...
Reposted today
HCM Cloud Platform & DevOps Engineer
$90K - $189K *
Manage the design, construction, and maintenance of cloud infrastructure for a federal HCM modernization initiative, ensuring secure, reliable environments and automating deployment processes across m...
Reposted 1 week ago
Manager, Cyber Incident Response
$110K - $170K *
Drive excellence in cyber incident response by leading a dynamic team, ensuring effective operations, and fostering collaboration across departments to safeguard against cyber threats in a fast-paced...
Yesterday
Director of Infrastructure Engineering
$152K - $273K *
Elevate infrastructure innovation by architecting automated, resilient multi-cloud environments, driving AI-first operations, and implementing Zero Trust security protocols across enterprise systems f...
Reposted today
Manager - Corporate IT Audit (SOC Reporting)
$101K - $203K *
Lead SOC audits and enhance control environments by managing audit processes, assessing risks, and developing team capabilities. Collaborate with stakeholders to ensure compliance and drive continuous...
Yesterday
Security & Infrastructure Engineer
$100K - $120K *
Drive security excellence by managing identity access, external testing, and compliance processes. Collaborate with teams to enhance AWS security and develop scalable policies, ensuring robust protect...
2 weeks ago
Security Engineer 4 (SWG, Remote Access)
$179K - $204K *
Champion innovative security solutions by designing automated controls and cloud architectures. Collaborate with cross-functional teams to enhance enterprise security and drive technical transformatio...
5 days ago
$90K - $110K *
Join a team that's focused on delivering mission-critical solutions. Contribute as a systems integrator, managing projects and advising leadership while ensuring technical excellence and effective com...
3 weeks ago
Subject Matter Expert - Remote Sensing/Nuclear Detection Activity
$150K - $180K *
Drive expertise in remote sensing and nuclear detection to analyze, evaluate, and communicate critical intelligence on nuclear proliferation. Collaborate with teams across sectors to enhance detection...
Reposted yesterday
Enterprise Service and Configuration Management Analyst
$66K - $106K *
Optimize IT service delivery by managing configuration items, analyzing operational data, and ensuring effective incident resolution. Collaborate with cross-functional teams to enhance service perform...
2 weeks ago
Incident Response Coordinator IV
$110K - $130K *
Join our team as you respond to urgent cybersecurity incidents, coordinating the mitigation and recovery processes while ensuring the safety of critical assets and information. Shape the future of cyb...
4 weeks ago
What is an Information Systems Security Officer (ISSO)?
An ISSO is a cybersecurity professional who helps protect an organization’s information systems by coordinating security controls, assessing risks, maintaining documentation, and supporting compliance and authorization activities.
What qualifications are commonly required for ISSO jobs?
Requirements vary, but employers commonly look for information security or IT experience, knowledge of security controls and risk management, and familiarity with relevant standards such as NIST guidance. Some positions may require a degree, professional certifications, or an active security clearance.
How much do Information Systems Security Officers earn?
Compensation varies by employer, location, experience, clearance, and job scope. Ladders focuses on vetted professional jobs paying $100,000 or more; check each listing for its stated salary or compensation details.
Where do ISSOs work?
ISSO roles are found in government and defense contracting, technology, healthcare, financial services, and other industries that manage sensitive or regulated information.
How can I find ISSO jobs paying $100,000 or more?
Browse Information Systems Security Officer listings on Ladders and review each posting’s compensation, qualifications, location, and clearance requirements to find roles that fit your experience.