Explore $100K+ Jobs in Iowa

Discover professional opportunities across Iowa with Ladders. Browse vetted job listings with salaries of $100,000 or more, from leadership and technology roles to finance, healthcare, engineering, and other specialized careers. Whether you’re considering a move or looking to advance your career close to home, explore opportunities in Iowa’s major employment centers and beyond.

Where to Find Professional Jobs in Iowa

Iowa offers career opportunities in cities and communities throughout the state. Des Moines is a major center for insurance, financial services, healthcare, and corporate leadership. Cedar Rapids and Iowa City have opportunities in technology, advanced manufacturing, education, and healthcare, while other regional hubs support a range of professional and industrial employers. Job availability and compensation vary by role, employer, and location.

In-Demand Fields and Roles

High-paying Iowa jobs can be found across industries such as insurance and finance, healthcare, information technology, engineering, manufacturing, agriculture-related business, and executive management. Employers may seek experienced professionals in areas including software and data, operations, sales, accounting, clinical leadership, and product or project management. Review each posting for its specific qualifications, responsibilities, and compensation details.

Find the Right Iowa Opportunity

Use Ladders to explore vetted professional openings with listed salaries of $100,000 or more. Refine your search by job title, industry, location, and other preferences. Compare roles and employer requirements, then apply to opportunities that align with your experience and career goals. Listings and salary information can change, so check individual postings for the latest details.

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1,000+

Healthcare Jobs in Iowa

Average Salary in USD

Average Salary: $109,869

Sort By: Relevance

$136K - $170K *

Partner with us to enhance patient access by leading market access strategies, educating teams, and collaborating across departments to ensure effective reimbursement for our innovative medical techno...

RemoteRemote

4 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$110K - $130K *

Transform early phase clinical trials by leading design, execution, and oversight. Collaborate with cross-functional teams to ensure compliance and data integrity while managing project performance an...

United StatesRemote

4 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$90K - $110K *

Analyze clinical documentation and risk adjustment for healthcare providers, ensuring accurate representation of patient acuity. Collaborate with physicians to identify documentation opportunities and...

United StatesRemote

4 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$164K - $247K *

Join a dynamic team to lead central monitoring efforts in clinical trials, driving data-driven insights and risk management strategies. Collaborate across functions to enhance monitoring efficiency an...

RemoteRemote

4 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$90K - $95K *

Drive the successful adoption of advanced hearing solutions by providing expert clinical support and education to healthcare professionals. Collaborate closely with cross-functional teams to enhance p...

United StatesRemote

4 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$110K - $130K *

Advance analytics and informatics solutions by integrating VA databases, developing dashboards, and collaborating in Agile teams to enhance healthcare delivery for Veterans, ensuring effective data ma...

United StatesRemote

4 weeks ago

  •   8 - 10 years exp.  •   Healthcare

$80K - $95K *

Drive revenue cycle optimization by enhancing Epic Professional Billing workflows, collaborating with stakeholders, and resolving claims challenges to improve overall operational efficiency and ensure...

United StatesRemote

4 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$90K - $110K *

Deliver high-quality virtual psychotherapy for older adults, crafting personalized treatment plans while enjoying flexible scheduling, administrative support, and a collaborative community to thrive i...

Iowa, USRemote

4 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$112K - $193K *

Transform pharmacy operations by enhancing consumer experiences, mentoring staff, and ensuring compliance. Lead financial growth while promoting quality health services and building strong community r...

4 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$250K - $300K *

Oversee and deliver exceptional diagnostic imaging services remotely, focusing on evening shifts. Collaborate within a dynamic team while managing varied inpatient and outpatient cases to support pati...

RemoteRemote

4 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$146K - $234K *

Lead critical CMS operations by providing expert guidance on Medicare Administrative Contractors, ensuring project teams leverage deep knowledge of MAC functions and regulations to enhance the Medicar...

United StatesRemote

4 weeks ago

  •   11 - 15 years exp.  •   Aerospace & Defense

$80K - $95K *

Join a team that's dedicated to transforming occupational health evaluations through virtual care. Utilize your expertise to assess diverse worker populations, direct care paths, and support workplace...

United StatesRemote

4 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$77K - $106K *

Contribute to high-quality patient care by leading a clinical team, overseeing operations, and ensuring compliance. Empower clinicians through guidance and education while fostering independence in pa...

4 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$250K *

Lead the charge in an established dental practice with strong patient demand while enjoying autonomy and support. Embrace professional growth through mentorship, advanced technology, and robust patien...

4 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$107K - $199K *

Redefine pharmacy care by developing formularies and policies, enhancing quality programs, and driving initiatives that improve Medicaid services while collaborating with diverse teams and stakeholder...

United StatesRemote

4 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$85K - $130K *

Champion change in healthcare IT consulting by leading enterprise software projects and enhancing organizational workflows. Collaborate with leadership, drive client success, and deliver impactful res...

United StatesRemote

4 weeks ago

  •   5 - 7 years exp.  •   Legal & Accounting

$100K - $120K *

Support clinical studies by assisting teams with tasks like medical monitoring and protocol management. Collaborate across functions and engage with stakeholders to ensure successful trial outcomes wh...

United StatesRemote

4 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$120K - $162K *

Drive pharmacy operations as a licensed Pharmacist, ensuring compliance, safety, and exceptional customer care. Lead a dedicated team while managing workflow, performance metrics, and process improvem...

United StatesRemote

Reposted 4 weeks ago

  •   Less than 5 years exp.  •   Retail & Consumer Goods

$100K - $120K *

Join a team that's redefining telehealth by delivering exceptional psychotherapy to older adults. Enjoy flexible hours, comprehensive support, and opportunities for professional growth while making a...

United StatesRemote

4 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$176K - $287K *

Lead the charge in advancing scientific discourse by engaging KOLs and HCPs in Hematological Malignancies. Drive strategic medical initiatives while fostering relationships to enhance research and cli...

United StatesRemote

4 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$110K - $130K *

Join a team that's dedicated to providing exceptional pharmacy consulting services while ensuring medication safety and compliance. Mentor colleagues and enhance patient health through education and i...

4 weeks ago

  •   Less than 5 years exp.  •   Retail & Consumer Goods

$110K - $130K *

Empower patients by delivering expert pharmacy consulting and care. Lead a collaborative team, ensuring medication safety and effective therapy management while mentoring team members. Join us in crea...

4 weeks ago

  •   Less than 5 years exp.  •   Retail & Consumer Goods

$110K - $130K *

Partner with us to deliver patient-centered pharmacy consulting and clinical services. Educate on medication management and ensure safe dispensing while mentoring a dedicated team in a collaborative e...

4 weeks ago

  •   Less than 5 years exp.  •   Retail & Consumer Goods

$262K - $404K *

Optimize patient care and operational leadership as you manage Anesthesia APP teams, ensure regulatory compliance, and build strong client relationships while driving growth in practices and enhancing...

United StatesRemote

4 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$110K - $130K *

Join a team that's committed to excellence in quality management, ensuring product integrity and compliance. You'll lead client-focused initiatives, partner with cross-functional teams, and drive cont...

4 weeks ago

  •   8 - 10 years exp.  •   Business Services

Frequently Asked Questions (FAQ)

  • What types of $100,000+ jobs are available in Iowa?question toggle

    Openings may include leadership, technology, finance and insurance, healthcare, engineering, sales, and operations roles. Availability depends on employer needs, experience, and location; review current listings for specific opportunities.

  • Which Iowa cities have professional jobs paying $100,000 or more?question toggle

    Des Moines, Cedar Rapids, and Iowa City are among the state’s major employment centers, with professional opportunities also available in other Iowa communities. Search by location to see current openings.

  • How can I find high-paying jobs in Iowa on Ladders?question toggle

    Browse Iowa listings and use filters such as job title, industry, and location. Ladders features vetted professional jobs with salaries of $100,000 or more; check each posting for qualifications and compensation details.

  • Do Iowa job listings on Ladders include salary information?question toggle

    Ladders focuses on jobs with salaries of $100,000 or more. Individual postings provide the available compensation information, which may vary by role and employer.