Explore $100K+ Jobs in Iowa

Discover professional opportunities across Iowa with Ladders. Browse vetted job listings with salaries of $100,000 or more, from leadership and technology roles to finance, healthcare, engineering, and other specialized careers. Whether you’re considering a move or looking to advance your career close to home, explore opportunities in Iowa’s major employment centers and beyond.

Where to Find Professional Jobs in Iowa

Iowa offers career opportunities in cities and communities throughout the state. Des Moines is a major center for insurance, financial services, healthcare, and corporate leadership. Cedar Rapids and Iowa City have opportunities in technology, advanced manufacturing, education, and healthcare, while other regional hubs support a range of professional and industrial employers. Job availability and compensation vary by role, employer, and location.

In-Demand Fields and Roles

High-paying Iowa jobs can be found across industries such as insurance and finance, healthcare, information technology, engineering, manufacturing, agriculture-related business, and executive management. Employers may seek experienced professionals in areas including software and data, operations, sales, accounting, clinical leadership, and product or project management. Review each posting for its specific qualifications, responsibilities, and compensation details.

Find the Right Iowa Opportunity

Use Ladders to explore vetted professional openings with listed salaries of $100,000 or more. Refine your search by job title, industry, location, and other preferences. Compare roles and employer requirements, then apply to opportunities that align with your experience and career goals. Listings and salary information can change, so check individual postings for the latest details.

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1,000+

Healthcare Jobs in Iowa

Average Salary in USD

Average Salary: $109,869

Sort By: Relevance

$120K - $145K *

Engage healthcare professionals and thought leaders by driving scientific discussions, supporting clinical research, and facilitating impactful medical strategies in the rare disease liver portfolio w...

United StatesRemote

Reposted 4 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$115K - $120K *

Join a team that's dedicated to delivering high-quality telehealth therapy, supporting clients through relationship and personal challenges. Enjoy a consistent schedule and competitive compensation wh...

Ankeny, IARemote

4 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$115K - $120K *

Unlock potential by providing high-quality telehealth therapy to individuals, couples, and families. Collaborate with clients to navigate relationship dynamics and personal challenges in a supportive...

4 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$120K - $165K *

Drive the successful transfer of CDI best practices by mentoring client teams, conducting record reviews, and delivering education. Collaborate with healthcare professionals to enhance documentation a...

United StatesRemote

4 weeks ago

  •   Less than 5 years exp.  •   Business Services

$256K - $347K *

Lead the charge in ensuring optimal safety standards for Rare Disease products. Establish pharmacovigilance strategies, oversee safety profiles, and engage cross-functional teams to deliver critical t...

United StatesRemote

Reposted 4 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$20K - $350K *

Contribute to compassionate podiatric care by providing services in skilled nursing and senior living facilities across multiple states. Enjoy flexible scheduling and support as you enhance patient ou...

Reposted 4 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$80K - $85K *

Elevate your career by managing the 340B Drug Pricing Program, ensuring compliance and operational excellence for diverse healthcare clients. Collaborate cross-functionally while driving program integ...

United StatesRemote

4 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$90K - $110K *

Empower patient care by functioning as an Advanced Practice Nurse, collaborating with interdisciplinary teams to deliver quality health services, educate staff, and drive research initiatives for impr...

4 weeks ago

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$152K - $253K *

Bring your expertise to enhance patient access and support, guiding oncology patients and healthcare providers on coverage, reimbursement, and treatment navigation while ensuring compliance and operat...

Reposted 4 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$152K - $253K *

Champion the patient journey in oncology as a key navigator, guiding patients and healthcare providers through access, reimbursement, and support solutions. Ensure compliance while enhancing the thera...

Reposted 4 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$152K - $253K *

Transform the patient journey by guiding oncology patients and providers through access, reimbursement, and support solutions. Collaborate to ensure effective onboarding and ongoing assistance in ther...

Reposted 4 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$152K - $253K *

Join a team that guides patients and healthcare providers through oncology treatment journeys, ensuring access to support and education throughout the therapy process, while navigating coverage and re...

Reposted 4 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$85K - $100K *

Transform patient care by providing comprehensive oncology navigation and support. Collaborate with a multidisciplinary team to enhance patient experiences and outcomes through effective communication...

United StatesRemote

4 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$90K - $150K *

Elevate healthcare performance by leading analytics-driven consulting engagements. Collaborate with clients to identify needs, deliver insights, and implement solutions while managing project economic...

United StatesRemote

4 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$85K - $100K *

Empower our team by overseeing clinical trial activities, managing resources, and ensuring compliance with established procedures. Collaborate with cross-functional teams to drive operational excellen...

United StatesRemote

4 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$101K - $136K *

Transform clinical documentation by crafting high-quality regulatory submissions. Collaborate with cross-functional teams to ensure compliance with FDA and ICH guidelines while managing timelines and...

United StatesRemote

4 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$85K - $97K *

Shape the future of healthcare by conducting clinical case reviews and enhancing product quality for an AI-driven clinical platform. Collaborate with care teams to ensure accurate alert functionality...

United StatesRemote

4 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$95K - $206K *

Join a dynamic team as a Clinician Player Coach, mentoring peers while delivering high-quality in-home evaluations. Balance clinical duties with mentorship, ensuring exceptional care and support for n...

RemoteRemote

4 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$78K - $168K *

Drive health outcomes by conducting in-home evaluations, building trust with patients, and providing personalized care. Travel extensively to meet diverse needs, ensuring comprehensive health assessme...

United StatesRemote

4 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$125K - $235K *

Transform healthcare operations by partnering with client leaders to ensure effective Revenue Integrity during Epic implementations. Leverage your expertise to drive informed decisions and optimize re...

United StatesRemote

4 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$85K - $100K *

Unlock your potential by providing direct patient care and collaborating with physicians. Engage in diagnostic and therapeutic services while educating future healthcare professionals in a dynamic pri...

4 weeks ago

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$80K - $95K *

Champion efficiency in the revenue cycle as you lead a dedicated billing team. Drive performance improvements, oversee compliance, and identify revenue opportunities while cultivating a culture of exc...

United StatesRemote

Reposted 4 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$95K - $115K *

Champion innovative solutions as a Business Solutions Analyst, collaborating with healthcare organizations to drive strategic initiatives and operational excellence across diverse projects and deliver...

United StatesRemote

4 weeks ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$125K - $150K *

Join a team that's redefining patient care through innovative leadership in care coordination. Drive operational excellence, enhance patient outcomes, and collaborate with multidisciplinary teams to i...

4 weeks ago

  •   5 - 7 years exp.  •   Education, Government & Non-Profit

$80K - $100K *

Join a team that's dedicated to delivering high-quality psychotherapy to older adults. Enjoy flexible scheduling, comprehensive support, and the opportunity to make a meaningful impact in a collaborat...

United StatesRemote

4 weeks ago

  •   Less than 5 years exp.  •   Healthcare

Frequently Asked Questions (FAQ)

  • What types of $100,000+ jobs are available in Iowa?question toggle

    Openings may include leadership, technology, finance and insurance, healthcare, engineering, sales, and operations roles. Availability depends on employer needs, experience, and location; review current listings for specific opportunities.

  • Which Iowa cities have professional jobs paying $100,000 or more?question toggle

    Des Moines, Cedar Rapids, and Iowa City are among the state’s major employment centers, with professional opportunities also available in other Iowa communities. Search by location to see current openings.

  • How can I find high-paying jobs in Iowa on Ladders?question toggle

    Browse Iowa listings and use filters such as job title, industry, and location. Ladders features vetted professional jobs with salaries of $100,000 or more; check each posting for qualifications and compensation details.

  • Do Iowa job listings on Ladders include salary information?question toggle

    Ladders focuses on jobs with salaries of $100,000 or more. Individual postings provide the available compensation information, which may vary by role and employer.