Discover professional opportunities across Iowa with Ladders. Browse vetted job listings with salaries of $100,000 or more, from leadership and technology roles to finance, healthcare, engineering, and other specialized careers. Whether you’re considering a move or looking to advance your career close to home, explore opportunities in Iowa’s major employment centers and beyond.
Iowa offers career opportunities in cities and communities throughout the state. Des Moines is a major center for insurance, financial services, healthcare, and corporate leadership. Cedar Rapids and Iowa City have opportunities in technology, advanced manufacturing, education, and healthcare, while other regional hubs support a range of professional and industrial employers. Job availability and compensation vary by role, employer, and location.
High-paying Iowa jobs can be found across industries such as insurance and finance, healthcare, information technology, engineering, manufacturing, agriculture-related business, and executive management. Employers may seek experienced professionals in areas including software and data, operations, sales, accounting, clinical leadership, and product or project management. Review each posting for its specific qualifications, responsibilities, and compensation details.
Use Ladders to explore vetted professional openings with listed salaries of $100,000 or more. Refine your search by job title, industry, location, and other preferences. Compare roles and employer requirements, then apply to opportunities that align with your experience and career goals. Listings and salary information can change, so check individual postings for the latest details.
Average Salary: $109,869
Clinical Scientist - Oncology - Home-based anywhere in the US - FSP
$110K - $130K *
Elevate your career by supporting clinical studies through scientific expertise, operational delivery, and compliance. Collaborate with cross-functional teams and stakeholders to ensure successful tri...
4 weeks ago
$80K - $95K *
Champion the installation, maintenance, and repair of life-saving medical devices. Manage service activities independently within a designated region, ensuring compliance and customer satisfaction thr...
4 weeks ago
Advanced Practice Provider (FT) | Physical Medicine & Rehabilitation | Ames | PR2026-016
$90K - $110K *
Manage patient care as an Advanced-Practice Provider in a collaborative team, leveraging a large referral network and comprehensive benefits to enhance the well-being of patients in a supportive envir...
4 weeks ago
Quality Assurance Director / Sr. Director (GVP/PV)
$213K - $280K *
Strategize and lead the GVP quality and compliance program, ensuring adherence to global regulations while collaborating across functions to enhance processes and systems. Drive audit programs and reg...
4 weeks ago
Manager/Sr. Manager, Analytical Development
$153K - $185K *
Join a dynamic team to manage analytical development and quality control activities, ensuring compliance and efficiency in drug substance and product processes. Collaborate closely with cross-function...
4 weeks ago
CRNA Tri-State Surgery Center - M-F daytime hours, no call, no weekends!
$160K - $200K *
Join a team that's dedicated to delivering exceptional anesthesia care in a dynamic surgery center. Enjoy a balanced schedule with no nights or call, while practicing independently with physician supp...
4 weeks ago
Deputy Chief of Party II, Technical, Continuity of Integrated Health Services
$95K - $117K *
Champion integrated health initiatives across multiple countries, providing strategic oversight and leadership for malaria, maternal health, and infectious disease programs. Ensure quality interventio...
4 weeks ago
$100K - $120K *
Empower your veterinary career by providing urgent care for pets in a supportive, modern environment. Collaborate with a dedicated team to manage diverse cases while enjoying a flexible schedule and o...
4 weeks ago
Director/Sr. Director Clinical Pharmacology
$262K - $284K *
Optimize pediatric drug development strategies as a clinical pharmacology leader, overseeing pharmacometric analyses and regulatory submissions, while translating complex data into actionable decision...
Reposted 4 weeks ago
Clinical Laboratory Supervisor
$91K - $100K *
Join a team that's dedicated to excellence in clinical lab operations, overseeing staff performance and ensuring compliance with quality standards. Lead daily activities, foster team development, and...
4 weeks ago
$102K - $120K *
Join a team that's transforming healthcare analytics by bridging complex data with strategic insights. Leverage your SQL expertise and analytics engineering skills to empower stakeholders and drive va...
4 weeks ago
Veterinarian up to $50,000 Sign-On Bonus, Osceola Veterinary Clinic-ADVM
$100K - $120K *
Champion high-quality small animal care by providing comprehensive medical services, fostering client relationships, and collaborating in a supportive environment that promotes professional growth and...
4 weeks ago
$80K - $95K *
Elevate the patient admission process by leading a dynamic team, ensuring high-quality service, meeting quotas, and implementing best practices. This role is essential in connecting clients with criti...
Reposted 4 weeks ago
Clinic Manager-Physical Therapist
$68K - $116K *
Join a dynamic team to lead clinic operations, enhance patient care, and foster employee development. Drive quality outcomes while utilizing innovative AI technology to streamline documentation and im...
4 weeks ago
Director of Clinical Quality and Outcomes (BCBA-D Preferred)
$110K - $130K *
Innovate clinical quality systems for scalable care delivery, ensuring standards meet payer expectations and driving measurable performance improvements across independent health providers...
Reposted 4 weeks ago
Director, Medical Science Liaison (Dallas, AR, LA, OK, MS)
$236K - $259K *
Join a team that advances medical knowledge and relationships in lung cancer. As a key liaison, engage with healthcare professionals, support scientific initiatives, and collaborate cross-functionally...
Reposted 4 weeks ago
$320K - $500K *
Join a dynamic clinical team as a psychiatrist, providing 100% outpatient care with flexible scheduling. Enjoy a supportive environment, competitive compensation, and a focus on work/life balance whil...
4 weeks ago
$378K - $420K *
Transform pharmacovigilance by leading a dedicated team, enhancing systems, and ensuring compliance across clinical and commercial products while driving safety strategy and governance...
4 weeks ago
Manager, Case Management (LCSW/LMFT)
$90K - $115K *
Champion clinical excellence by leading and mentoring a dynamic ECM team, ensuring comprehensive patient care and adherence to individualized plans, while collaborating effectively with multidisciplin...
Reposted 4 weeks ago
Director, Head of Patient Recruitment and Retention, Americas
$171K - $231K *
Drive innovative patient recruitment strategies to enhance clinical trial enrollment and retention. Collaborate with cross-functional teams to implement data-driven approaches, optimize patient engage...
Reposted 4 weeks ago
PMHNP Psychiatric Mental Health Nurse Practitioner
$175K - $275K *
Shape the future of mental health care by delivering exceptional outpatient services. Join a dynamic team focused on patient-centered treatment, leveraging modern technology and flexible schedules to...
4 weeks ago
$80K - $95K *
Join our Clinical Science team to enhance data integrity in CNS trials by conducting meticulous reviews of clinical interviews, ensuring protocol compliance, and guiding site interventions as a Clinic...
Reposted 4 weeks ago
$80K - $95K *
Drive excellence in embryology by performing core IVF procedures, ensuring compliance with quality standards, and contributing to laboratory optimization and patient care in a dynamic team environment...
4 weeks ago
Telehealth Psychiatric Nurse Practitioner - Eating Disorders (EST - Remote)
$120K - $150K *
Join a team that's dedicated to transforming the mental health landscape, providing comprehensive telehealth care for individuals with eating disorders while collaborating closely with a multidiscipli...
Reposted 4 weeks ago
$150K - $180K *
Join a dynamic team to lead and scale clinical operations, overseeing performance and process optimization. Build accountable teams, manage metrics, and partner with stakeholders to enhance operationa...
Reposted 4 weeks ago
What types of $100,000+ jobs are available in Iowa?
Openings may include leadership, technology, finance and insurance, healthcare, engineering, sales, and operations roles. Availability depends on employer needs, experience, and location; review current listings for specific opportunities.
Which Iowa cities have professional jobs paying $100,000 or more?
Des Moines, Cedar Rapids, and Iowa City are among the state’s major employment centers, with professional opportunities also available in other Iowa communities. Search by location to see current openings.
How can I find high-paying jobs in Iowa on Ladders?
Browse Iowa listings and use filters such as job title, industry, and location. Ladders features vetted professional jobs with salaries of $100,000 or more; check each posting for qualifications and compensation details.
Do Iowa job listings on Ladders include salary information?
Ladders focuses on jobs with salaries of $100,000 or more. Individual postings provide the available compensation information, which may vary by role and employer.