Explore $100K+ Jobs in Iowa

Discover professional opportunities across Iowa with Ladders. Browse vetted job listings with salaries of $100,000 or more, from leadership and technology roles to finance, healthcare, engineering, and other specialized careers. Whether you’re considering a move or looking to advance your career close to home, explore opportunities in Iowa’s major employment centers and beyond.

Where to Find Professional Jobs in Iowa

Iowa offers career opportunities in cities and communities throughout the state. Des Moines is a major center for insurance, financial services, healthcare, and corporate leadership. Cedar Rapids and Iowa City have opportunities in technology, advanced manufacturing, education, and healthcare, while other regional hubs support a range of professional and industrial employers. Job availability and compensation vary by role, employer, and location.

In-Demand Fields and Roles

High-paying Iowa jobs can be found across industries such as insurance and finance, healthcare, information technology, engineering, manufacturing, agriculture-related business, and executive management. Employers may seek experienced professionals in areas including software and data, operations, sales, accounting, clinical leadership, and product or project management. Review each posting for its specific qualifications, responsibilities, and compensation details.

Find the Right Iowa Opportunity

Use Ladders to explore vetted professional openings with listed salaries of $100,000 or more. Refine your search by job title, industry, location, and other preferences. Compare roles and employer requirements, then apply to opportunities that align with your experience and career goals. Listings and salary information can change, so check individual postings for the latest details.

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1,000+

Healthcare Jobs in Iowa

Average Salary in USD

Average Salary: $109,869

Sort By: Relevance

$120K - $145K *

Lead the design and governance of clinical ontologies and terminology services, ensuring data quality and alignment with product needs. Collaborate cross-functionally to enhance data normalization and...

United StatesRemote

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  •   5 - 7 years exp.  •   Healthcare

$90K - $108K *

Lead the charge in delivering high-quality nursing care while guiding and training staff. Collaborate with leadership to develop policies, ensure compliance, and enhance clinical practices in a suppor...

Today

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$110K - $130K *

Innovate data-driven product strategies by leading informatics initiatives, ensuring rigorous testing and quality assessments while collaborating across teams to enhance client services and streamline...

United StatesRemote

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  •   5 - 7 years exp.  •   Healthcare

$72K - $93K *

Empower patients through tailored speech therapy solutions. Join a dynamic team focused on innovative care, flexible scheduling, and professional growth in a supportive environment dedicated to achiev...

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  •   Less than 5 years exp.  •   Healthcare

$108K *

Lead nursing operations in an acute care setting, ensuring high-quality patient care and compliance with standards. Oversee staff development, manage departmental budgets, and collaborate with healthc...

Today

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$69K - $119K *

Transform the landscape of clinical documentation by educating and mentoring teams, ensuring compliance, and enhancing documentation accuracy to optimize patient care and coding outcomes...

United StatesRemote

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  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$82K - $132K *

Unlock potential in revenue cycle management by leading innovative solutions, optimizing processes, and collaborating across departments to enhance operational efficiency and maximize revenue impact...

United StatesRemote

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  •   5 - 7 years exp.  •   Healthcare

$80K - $95K *

Join a team that's dedicated to enhancing patient care by supervising and supporting a diverse rehab team, ensuring effective clinical programs, and fostering collaboration for quality outcomes in a l...

Today

  •   Less than 5 years exp.  •   Healthcare

$134K - $249K *

Lead the charge in enhancing clinical systems operations, driving efficiency and effectiveness across pharmacy initiatives while managing a dedicated team and overseeing complex workflows and data int...

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  •   5 - 7 years exp.  •   Healthcare

$150K - $180K *

Drive strategic clinical operations and program development to enhance patient outcomes. Lead a multidisciplinary team, ensuring compliance and effective care coordination across acute and post-acute...

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  •   8 - 10 years exp.  •   Healthcare

$110K - $200K *

Join a team that's dedicated to advancing clinical research by leading operational aspects of trials, ensuring compliance with protocols and regulations, and fostering collaboration among stakeholders...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Healthcare

$187K - $281K *

Redefine market access strategies by leading payer engagement to enhance patient access to genomic testing. Collaborate cross-functionally to drive favorable coverage and reimbursement policies, ensur...

United StatesRemote

Today

  •   15+ years exp.  •   Pharmaceuticals & Biotech

$88K - $105K *

Transform patient care in Emergency Medicine by leading clinical practice, enhancing outcomes, and fostering innovation. Collaborate with a multidisciplinary team to implement evidence-based standards...

Today

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$180K - $220K *

Lead the evaluation of outpatient referrals and inpatient admissions for medical necessity, utilizing guidelines and criteria to ensure quality care. Collaborate with providers and mentor UM nurses to...

United StatesRemote

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  •   5 - 7 years exp.  •   Healthcare

$160K - $200K *

Drive strategic growth and operational excellence in cardiology, fostering physician partnerships and overseeing clinical and financial performance to enhance patient care and organizational success...

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  •   8 - 10 years exp.  •   Healthcare

$100K - $120K *

Elevate your career by designing and optimizing EpicCare Ambulatory workflows. Collaborate with clinicians to enhance EHR functionality, troubleshoot issues, and ensure seamless operations across heal...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Healthcare

$210K - $250K *

Empower a dynamic team of reimbursement professionals to enhance provider access and education. Drive strategic initiatives, foster collaboration, and ensure compliance while navigating complex payer...

United StatesRemote

Today

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$85K - $100K *

Join us to lead nursing practice across ambulatory and inpatient areas, enhancing patient care through education, consultation, and research. Collaborate with clinical leaders to improve orthopedic ca...

Today

  •   Less than 5 years exp.  •   Healthcare

$138K - $187K *

Lead cross-functional quality initiatives to enhance product health and compliance. Collaborate with diverse teams on regulatory submissions, quality assessments, and process improvements for late-sta...

United StatesRemote

Today

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$93K - $104K *

Join a dynamic team to deliver high-quality audiologic evaluations remotely. Leverage your expertise in a supportive environment, enhancing patient care while minimizing administrative burdens and max...

United StatesRemote

Today

  •   Less than 5 years exp.  •   Healthcare

$97K - $145K *

Join a dynamic team to lead physician coding integration initiatives, ensuring operational readiness and compliance. Collaborate across departments to enhance coding practices and drive revenue cycle...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Hospitals & Medical Centers

$92K - $125K *

Drive operational excellence in patient access by leading teams, enhancing processes, and fostering collaboration across healthcare facilities. Your leadership will ensure compliance, improve patient...

United StatesRemote

Today

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$83K - $104K *

Elevate patient care by providing comprehensive nursing services in a behavioral health setting. Collaborate with a dedicated team to assess, implement, and monitor treatment plans while ensuring safe...

Today

  •   Less than 5 years exp.  •   Healthcare

$215K - $408K *

Drive medical leadership in quality improvement and utilization management, ensuring effective care delivery and cost containment. Collaborate with clinical teams to enhance patient outcomes and suppo...

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  •   Less than 5 years exp.  •   Healthcare

$110K - $130K *

Join our team to drive innovation in eye care by presenting scientific insights, fostering relationships with medical experts, and influencing strategies to enhance patient outcomes through evidence-b...

RemoteRemote

Today

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

Frequently Asked Questions (FAQ)

  • What types of $100,000+ jobs are available in Iowa?question toggle

    Openings may include leadership, technology, finance and insurance, healthcare, engineering, sales, and operations roles. Availability depends on employer needs, experience, and location; review current listings for specific opportunities.

  • Which Iowa cities have professional jobs paying $100,000 or more?question toggle

    Des Moines, Cedar Rapids, and Iowa City are among the state’s major employment centers, with professional opportunities also available in other Iowa communities. Search by location to see current openings.

  • How can I find high-paying jobs in Iowa on Ladders?question toggle

    Browse Iowa listings and use filters such as job title, industry, and location. Ladders features vetted professional jobs with salaries of $100,000 or more; check each posting for qualifications and compensation details.

  • Do Iowa job listings on Ladders include salary information?question toggle

    Ladders focuses on jobs with salaries of $100,000 or more. Individual postings provide the available compensation information, which may vary by role and employer.