Explore $100K+ Jobs in Iowa

Find professional opportunities across Iowa with salaries of $100,000 or more. From Des Moines and Cedar Rapids to Iowa City, Davenport, and beyond, Ladders helps experienced professionals discover vetted roles that match their skills and career goals.

High-Paying Careers Across Iowa

Iowa employers hire experienced professionals in fields such as healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Available positions and compensation vary by employer, location, and experience, so explore listings to see which opportunities fit your background.

Where to Find Iowa Opportunities

Search jobs in major employment centers including Des Moines, Cedar Rapids, Iowa City, Davenport, and Sioux City, as well as remote and hybrid roles that may be available to candidates in Iowa. Use location and job-title filters to focus your search.

Find a Role That Fits Your Experience

Compare responsibilities, qualifications, and compensation details across openings. Keep your resume current, tailor applications to each position, and set up job alerts to stay informed when relevant high-paying jobs are posted.

Search Vetted Professional Jobs on Ladders

Ladders focuses on professional opportunities paying $100,000 or more. Browse Iowa listings to find your next career move and connect with roles suited to your expertise.

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1,000+

Healthcare Jobs in Iowa

Average Salary in USD

Average Salary: $109,865

Sort By: Relevance

$83K - $95K *

Inspire healthy smiles by providing exceptional dental care and education. Collaborate with a dedicated team to enhance patient experiences and promote long-term oral health in a supportive, modern en...

2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$130K - $160K *

Oversee the operational planning and execution of clinical trials, ensuring compliance with regulatory standards while managing cross-functional teams to meet project timelines, budgets, and quality o...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$100K - $140K *

Empower patient care by providing clinical support and training to surgical teams. Collaborate closely with healthcare professionals to ensure optimal outcomes and maintain equipment standards while m...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$250K - $350K *

Lead the development of a clinical supply consulting practice, combining expertise in forecasting, planning, and optimization to enhance decision-making for sponsors. Drive innovation and commercial g...

United StatesRemote

2 weeks ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$300K *

Elevate healthcare delivery by leading a dedicated team in clinical evaluations, ensuring best practices while providing client-facing support and expertise in medical claims, regulations, and emergin...

United StatesRemote

Reposted 2 weeks ago

  •   8 - 10 years exp.  •   Finance & Insurance

$70K - $95K *

Join a team that provides compassionate care by assessing and addressing patients' physical and behavioral health needs, developing tailored nursing plans, and ensuring compliance with medical protoco...

2 weeks ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$80K - $95K *

Transform credentialing operations by leading a dedicated team to ensure compliance, enhance efficiency, and support provider network growth through strategic oversight and process improvement initiat...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$90K - $110K *

Lead a dynamic team to enhance home health services, ensuring compliance, quality, and financial growth through strategic planning and collaboration with stakeholders. Drive innovative solutions to me...

2 weeks ago

  •   5 - 7 years exp.  •   Hospitals & Medical Centers

$235K - $270K *

Drive your career forward by leading access strategies across the Central region. Manage key payer relationships and ensure launch readiness for rare disease products while collaborating with cross-fu...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$113K - $188K *

Shape the future of healthcare reimbursement by developing and implementing payment policies that enhance accuracy, compliance, and provider experience in a dynamic payer environment. Collaborate with...

RemoteRemote

2 weeks ago

  •   5 - 7 years exp.  •   Business Services

$140K - $168K *

Transform nursing operations across multiple skilled nursing facilities by providing clinical oversight, mentorship, and support. Collaborate with leadership to ensure high-quality care, regulatory co...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$132K - $199K *

Join a team that's committed to transparency in clinical trials, ensuring compliance with global disclosure regulations. This role blends operational and strategic tasks, fostering collaboration and q...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$83K - $104K *

Empower individuals by providing exceptional audiology services in a supportive environment. Join our dedicated team to enhance the hearing health of both adults and children, ensuring a positive impa...

2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$248K - $461K *

Grow your career with us by providing strategic medical leadership for oncology agent development, coordinating clinical strategies, guiding trials, and collaborating with international experts to dri...

United StatesRemote

Reposted 2 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$69K - $95K *

Drive impactful change by ensuring donor safety and eligibility in a dynamic plasma donation environment. Collaborate with medical professionals to deliver high-quality care and support life-saving tr...

2 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$85K - $100K *

Join a team that's dedicated to empowering veterinarians with flexible schedules, clinical autonomy, and a supportive community, allowing you to thrive both professionally and personally while deliver...

2 weeks ago

  •   Less than 5 years exp.  •   Staffing

$109K - $136K *

Drive accurate, evidence-based clinical claims while collaborating with Marketing, Legal, and Clinical teams. Build and manage the claims framework and evidence library to support bold, compliant mark...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$85K - $90K *

Elevate community engagement by building trusted relationships with senior living staff and residents. Act as a vital connector, ensuring seamless access to on-site care services while fostering colla...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$80K - $95K *

Lead the clinical review and resolution of psychiatric complaints, enhancing care quality across the network. Collaborate with clinical teams, investigate cases, and provide direct patient care, ensur...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$110K - $130K *

Join us to lead the development and execution of clinical study designs, ensuring effective project management and collaboration across teams. Your expertise will drive the success of clinical trials...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Staffing

$210K - $250K *

Explore a rewarding opportunity as an Outpatient Internal Medicine Physician, joining a collaborative team of 14 in a supportive environment. Enjoy flexible scheduling, no nights or weekends, and a fo...

2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$275K - $350K *

Transform cancer care by delivering high-quality, evidence-based oncology services via telehealth. Collaborate with multidisciplinary teams to enhance patient outcomes and develop innovative care mode...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$245K - $265K *

Optimize partnerships with Medical Experts to enhance neurology care. Drive strategic insights and educational initiatives while collaborating across teams to influence business decisions and improve...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$115K - $120K *

Join a dedicated team providing remote therapy to clients navigating relationship and mental health challenges. Enjoy a consistent schedule and competitive compensation while making a meaningful impac...

Iowa, USRemote

2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$115K - $120K *

Provide high-quality telehealth therapy to individuals, couples, and families, addressing relationship and mental health challenges. Collaborate with clients to set treatment goals and maintain compli...

2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

Frequently Asked Questions (FAQ)

  • What kinds of $100,000+ jobs are available in Iowa?question toggle

    Listings may include opportunities in healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Roles and salary ranges vary by employer and experience.

  • Which Iowa cities have professional jobs listed?question toggle

    Explore opportunities in Des Moines, Cedar Rapids, Iowa City, Davenport, Sioux City, and other Iowa locations. Remote or hybrid openings may also be available.

  • Are all jobs on this page guaranteed to pay at least $100,000?question toggle

    Ladders focuses on professional jobs paying $100,000 or more, but compensation and eligibility can vary. Review each listing for its specific salary information and requirements.

  • How can I find the right high-paying job in Iowa?question toggle

    Use filters for location, job title, and other preferences, then compare responsibilities and qualifications. Keeping your resume updated and setting job alerts can help you respond to relevant openings.