Explore $100K+ Jobs in Iowa

Find professional opportunities across Iowa with salaries of $100,000 or more. From Des Moines and Cedar Rapids to Iowa City, Davenport, and beyond, Ladders helps experienced professionals discover vetted roles that match their skills and career goals.

High-Paying Careers Across Iowa

Iowa employers hire experienced professionals in fields such as healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Available positions and compensation vary by employer, location, and experience, so explore listings to see which opportunities fit your background.

Where to Find Iowa Opportunities

Search jobs in major employment centers including Des Moines, Cedar Rapids, Iowa City, Davenport, and Sioux City, as well as remote and hybrid roles that may be available to candidates in Iowa. Use location and job-title filters to focus your search.

Find a Role That Fits Your Experience

Compare responsibilities, qualifications, and compensation details across openings. Keep your resume current, tailor applications to each position, and set up job alerts to stay informed when relevant high-paying jobs are posted.

Search Vetted Professional Jobs on Ladders

Ladders focuses on professional opportunities paying $100,000 or more. Browse Iowa listings to find your next career move and connect with roles suited to your expertise.

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1,000+

Healthcare Jobs in Iowa

Average Salary in USD

Average Salary: $109,865

Sort By: Relevance

$100K - $120K *

Unlock potential by delivering comprehensive health assessments in patients' homes. This role requires extensive travel within a region, ensuring quality care and education while collaborating with he...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$100K - $120K *

Drive comprehensive health assessments by traveling to patients' homes, ensuring accurate documentation and patient education. Collaborate with healthcare teams to enhance care continuity while managi...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$110K - $125K *

Elevate healthcare operations by leading credentialing and medical staff services across multiple states. Drive compliance, streamline onboarding, and enhance workflows to support over 200 professiona...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$175K - $210K *

Drive the execution of a comprehensive medical affairs plan for prostate cancer theranostics, collaborating across functions to enhance strategy, launch readiness, and lifecycle planning while advanci...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$78K - $206K *

Unlock potential by leading clinical performance improvement projects for Medicare Provider Collaboration groups. Collaborate with teams to enhance population health outcomes, focusing on Stars qualit...

RemoteRemote

2 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$175K - $210K *

Champion the execution of a comprehensive medical affairs plan for renal cancer theranostics, driving cross-functional alignment and strategic initiatives to enhance patient outcomes and advance clini...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$94K - $148K *

Optimize patient access by educating healthcare providers on reimbursement processes. As a Field Reimbursement Specialist, you'll navigate complex insurance challenges, ensuring patients receive speci...

RemoteRemote

2 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$235K - $329K *

Lead clinical pharmacology initiatives, overseeing drug development across infectious disease and oncology programs. Collaborate with cross-functional teams to drive strategic advancements and ensure...

United StatesRemote

2 weeks ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$200K - $270K *

Lead the development and execution of GxP quality systems, ensuring compliance and oversight for clinical and CMC quality. Drive vendor qualification, audits, and training while fostering a culture of...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$117K - $189K *

Join a team that's shaping the future of pharmaceutical quality by leading compliance initiatives and building a robust Quality Management System to support innovative therapies in a dynamic, collabor...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$135K - $176K *

Explore a rewarding opportunity to enhance healthcare access and quality. Collaborate with a dedicated team to support patients on their health journeys, driving impactful change in a dynamic environm...

Reposted 2 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$81K *

Lead and innovate clinic operations by managing staff, enhancing service quality, and ensuring efficient fiscal practices. Drive continuous improvement while fostering a collaborative environment to a...

2 weeks ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$80K - $95K *

Optimize coding education and compliance for healthcare providers. Lead a team to enhance clinical documentation, develop training plans, and ensure adherence to regulations, driving improvements in b...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$80K - $95K *

Elevate your career by managing coding operations, ensuring accuracy and compliance across healthcare settings. Lead educational initiatives for staff, optimize workflows, and drive improvements in co...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$150K - $245K *

Drive the execution of companion diagnostics strategy, managing cross-functional teams and partnerships to ensure successful assay development and regulatory compliance, ultimately enhancing patient o...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$77K - $92K *

Join a dynamic team as a Medical Writer, where you'll interpret complex clinical protocols and create essential documentation for clinical studies, ensuring high-quality standards and regulatory compl...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$110K - $150K *

Elevate payment integrity operations by leading a team focused on dispute resolution, compliance, and provider education. Drive data analysis and operational excellence to enhance collaborative relati...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$110K - $138K *

Lead the charge in clinical trial monitoring, ensuring compliance and quality. Collaborate with teams to enhance data integrity and site performance while providing training and support to maintain hi...

RemoteRemote

2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$124K - $280K *

Transform healthcare through AI and ML solutions, leading teams to develop impactful data-driven strategies. Drive innovation in clinical decision support and operational efficiency while engaging wit...

2 weeks ago

  •   11 - 15 years exp.  •   Legal & Accounting

$80K - $95K *

Join a dynamic team to lead clinical operations in Ophthalmic Surgery, enhancing patient care and efficiency. Collaborate with staff to implement best practices and drive process improvements while en...

2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$98K - $172K *

Champion patient care by providing pharmaceutical services, counseling, and immunizations. Engage with the community while ensuring compliance with regulations and fostering a supportive pharmacy envi...

2 weeks ago

  •   Less than 5 years exp.  •   Retail & Consumer Goods

$160K - $200K *

Transform patient care by delivering high-quality anesthesia services in diverse settings. Collaborate with a dedicated team while promoting a culture of continuous learning and professional integrity...

2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$190K - $300K *

Engage with scientific leaders to exchange medical insights and support research initiatives. Drive scientific discussions, enhance understanding of therapeutic areas, and foster collaboration within...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$74K - $129K *

Elevate healthcare delivery by managing operations for a nationwide virtual medical team. Collaborate with leaders to optimize patient care, drive performance improvements, and implement innovative wo...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Retail & Consumer Goods

$110K - $130K *

Champion innovative oncology pharmacy services, providing expert patient care and education while collaborating with healthcare teams. Elevate your career through clinical practice, residency training...

2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

Frequently Asked Questions (FAQ)

  • What kinds of $100,000+ jobs are available in Iowa?question toggle

    Listings may include opportunities in healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Roles and salary ranges vary by employer and experience.

  • Which Iowa cities have professional jobs listed?question toggle

    Explore opportunities in Des Moines, Cedar Rapids, Iowa City, Davenport, Sioux City, and other Iowa locations. Remote or hybrid openings may also be available.

  • Are all jobs on this page guaranteed to pay at least $100,000?question toggle

    Ladders focuses on professional jobs paying $100,000 or more, but compensation and eligibility can vary. Review each listing for its specific salary information and requirements.

  • How can I find the right high-paying job in Iowa?question toggle

    Use filters for location, job title, and other preferences, then compare responsibilities and qualifications. Keeping your resume updated and setting job alerts can help you respond to relevant openings.