Find professional opportunities across Iowa with salaries of $100,000 or more. From Des Moines and Cedar Rapids to Iowa City, Davenport, and beyond, Ladders helps experienced professionals discover vetted roles that match their skills and career goals.
Iowa employers hire experienced professionals in fields such as healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Available positions and compensation vary by employer, location, and experience, so explore listings to see which opportunities fit your background.
Search jobs in major employment centers including Des Moines, Cedar Rapids, Iowa City, Davenport, and Sioux City, as well as remote and hybrid roles that may be available to candidates in Iowa. Use location and job-title filters to focus your search.
Compare responsibilities, qualifications, and compensation details across openings. Keep your resume current, tailor applications to each position, and set up job alerts to stay informed when relevant high-paying jobs are posted.
Ladders focuses on professional opportunities paying $100,000 or more. Browse Iowa listings to find your next career move and connect with roles suited to your expertise.
Average Salary: $109,865
Manager, AI & Workflow Operations - Licensed (RN, NP, PA, or MD, RPh, PharmD)
$100K - $120K *
Transform healthcare delivery by leading operations for a growing telehealth practice. Collaborate with clinical teams to enhance patient care through innovative solutions and efficient workflows, ens...
1 week ago
EHR Application Analyst - Senior
$78K - $104K *
Inspire efficient EHR system performance by leading applications analysis and optimization. Drive project management and collaboration while mentoring team members and enhancing patient care through e...
Reposted 1 week ago
Manager Professional Billing Coding Operations - Remote
$78K - $113K *
Join us to lead the Professional Coding Operations team, ensuring accurate coding practices and compliance. Collaborate with stakeholders, mentor staff, and drive improvements in coding efficiency and...
1 week ago
Director, Global Real-World Evidence & Health Outcomes Scientist, Oncology
$204K - $340K *
Lead the charge in generating impactful real-world evidence to support oncology products, ensuring alignment with market needs and regulatory requirements while collaborating across teams to drive evi...
1 week ago
Quality of Care and Clinical Review Nurse
$69K - $125K *
Join a dynamic team to oversee quality of care investigations and improvement initiatives, ensuring compliance with regulatory standards while enhancing patient outcomes and organizational efficiency...
1 week ago
$130K - $150K *
Champion clinical project success by leading operations, training teams, and ensuring compliance. Drive strategic planning and risk management while overseeing site performance and fostering collabora...
1 week ago
Specialist, Clinical Implementations (Clinical Licensure Required) - REMOTE
$80K - $95K *
Innovate clinical system implementations by ensuring seamless integration of technologies and workflows. Collaborate with clinical and technical teams to enhance patient care and operational efficienc...
1 week ago
$210K - $250K *
Innovate in AI-native primary care by leading a dynamic medical group. Manage physicians, enhance care delivery, and shape clinical programs while maintaining direct patient care involvement. Drive ex...
1 week ago
Sr. CRA, FSP - Surgical / Medical Device - Central region
$130K - $133K *
Advance clinical research by leading site monitoring and management efforts. Ensure compliance with regulatory standards while overseeing study protocols and data integrity. Collaborate with teams to...
1 week ago
Senior Director, Medical Affairs Strategy & Launch--Hematology
$247K - $309K *
Unlock potential by leading medical strategy for hematologic malignancies. Collaborate cross-functionally to drive evidence generation, stakeholder engagement, and launch readiness, ensuring impactful...
1 week ago
Associate Director, Clinical Performance Management
$110K - $130K *
Drive enterprise clinical performance initiatives, translating executive priorities into actionable plans. Lead cross-functional teams, establish governance structures, and ensure accountability for s...
1 week ago
Care Manager RN - UM (Full-Time) Weekends (Remote)
$68K - $105K *
Advance healthcare quality by implementing utilization management strategies. Analyze data for provider enhancement and member satisfaction, while promoting efficient care delivery through collaborati...
Reposted 1 week ago
$85K - $105K *
Join a team that's dedicated to delivering impactful medical communications. As a Senior Account Manager, you'll lead strategic projects for pharmaceutical clients, ensuring quality and timely executi...
1 week ago
$90K - $110K *
Champion patient care by evaluating and managing chronic pain conditions, collaborating with healthcare teams to create tailored treatment plans that enhance quality of life and optimize outcomes for...
1 week ago
Regional Medical Science Director (South)
$200K - $235K *
Unlock potential by driving scientific excellence as a strategic partner, educating healthcare professionals on Immuno-Oncology and fostering relationships that support cancer therapeutic initiatives...
Reposted 1 week ago
Remote Telehealth Registered Dietitian | FT W2
$65K - $105K *
Contribute to transformative care for underserved women by analyzing assessments, providing counseling, and collaborating with healthcare professionals in a fully remote setting. Your expertise will e...
1 week ago
$95K - $115K *
Transform patient care by evaluating and managing chronic pain conditions. Collaborate with healthcare teams to create tailored treatment plans that enhance quality of life and optimize patient outcom...
1 week ago
Manager of Epic Applications (Clinical - Ancillary) | 40 hours a week | Informatics
$119K *
Join a dynamic team to oversee Epic applications, ensuring seamless integration and optimization across clinical services. Drive improvements in workflows and enhance patient care through effective ma...
1 week ago
Manager of Epic Applications (Clinical - Ancillary) | 40 hours a week | Informatics
$119K *
Join us in optimizing Epic applications to enhance clinical workflows and patient care. Lead a team of analysts, ensuring seamless integration and functionality across departments while driving contin...
1 week ago
ASC Pre/Recovery/PACU Staff Nurse 50% to 100%
$57K - $105K *
Join a team that's dedicated to providing exceptional pre and post-operative care. As a Staff Nurse, you'll assess patient needs, deliver quality nursing care, and lead a collaborative healthcare team...
1 week ago
Associate Director, Clinical Performance Management
$110K - $130K *
Champion clinical performance management by leading cross-functional initiatives, translating executive priorities into actionable plans, and ensuring accountability across the organization to drive s...
1 week ago
Field Reimbursement Manager - Northern CA
$185K - $230K *
Shape the future of community access by developing strategies to optimize reimbursement processes, collaborating with stakeholders, and ensuring compliance with healthcare regulations while enhancing...
1 week ago
Clinical Manager - Anesthesia Department
$80K - $95K *
Unlock your potential as a Clinical Manager, overseeing Anesthesia operations. Lead teams, manage budgets, and ensure quality patient care in a dynamic healthcare environment while fostering positive...
Reposted 1 week ago
Senior Director/VP - Translational Medicine & Pharmacology
$210K - $250K *
Drive the translational strategy for immunology therapies, focusing on biomarker development and clinical pharmacology. Collaborate cross-functionally to advance pipeline assets and support regulatory...
1 week ago
Clinical Applications Specialist, General Imaging Ultrasound- Boston
$110K - $165K *
Join a team that's dedicated to enhancing clinical education and customer experience. In this role, you'll drive training strategies and support ultrasound product implementation, impacting patient ca...
1 week ago
What kinds of $100,000+ jobs are available in Iowa?
Listings may include opportunities in healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Roles and salary ranges vary by employer and experience.
Which Iowa cities have professional jobs listed?
Explore opportunities in Des Moines, Cedar Rapids, Iowa City, Davenport, Sioux City, and other Iowa locations. Remote or hybrid openings may also be available.
Are all jobs on this page guaranteed to pay at least $100,000?
Ladders focuses on professional jobs paying $100,000 or more, but compensation and eligibility can vary. Review each listing for its specific salary information and requirements.
How can I find the right high-paying job in Iowa?
Use filters for location, job title, and other preferences, then compare responsibilities and qualifications. Keeping your resume updated and setting job alerts can help you respond to relevant openings.