Explore $100K+ Jobs in Iowa

Find professional opportunities across Iowa with salaries of $100,000 or more. From Des Moines and Cedar Rapids to Iowa City, Davenport, and beyond, Ladders helps experienced professionals discover vetted roles that match their skills and career goals.

High-Paying Careers Across Iowa

Iowa employers hire experienced professionals in fields such as healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Available positions and compensation vary by employer, location, and experience, so explore listings to see which opportunities fit your background.

Where to Find Iowa Opportunities

Search jobs in major employment centers including Des Moines, Cedar Rapids, Iowa City, Davenport, and Sioux City, as well as remote and hybrid roles that may be available to candidates in Iowa. Use location and job-title filters to focus your search.

Find a Role That Fits Your Experience

Compare responsibilities, qualifications, and compensation details across openings. Keep your resume current, tailor applications to each position, and set up job alerts to stay informed when relevant high-paying jobs are posted.

Search Vetted Professional Jobs on Ladders

Ladders focuses on professional opportunities paying $100,000 or more. Browse Iowa listings to find your next career move and connect with roles suited to your expertise.

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1,000+

Healthcare Jobs in Iowa

Average Salary in USD

Average Salary: $109,865

Sort By: Relevance

$162K - $224K *

Champion innovative MRI solutions by leveraging clinical expertise and project management skills to enhance healthcare performance and patient outcomes. Collaborate with teams to optimize workflows an...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Healthcare

$124K - $171K *

Transform healthcare outcomes by leading large-scale lab diagnostics deals. Drive revenue growth and customer retention through strategic planning, relationship building, and effective execution in a...

RemoteRemote

1 week ago

  •   5 - 7 years exp.  •   Healthcare

$80K - $110K *

Optimize customer satisfaction by servicing and maintaining medical imaging equipment. Leverage your expertise to install, troubleshoot, and train operators, while managing financial performance and f...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Healthcare

$150K - $180K *

Empower medical initiatives by leading project teams, providing strategic guidance, and ensuring compliance with regulatory standards while fostering high-performing teams in a dynamic environment...

RemoteRemote

1 week ago

  •   5 - 7 years exp.  •   Healthcare

$110K - $130K *

Transform your career with a pivotal role in clinical research, leading oncology studies and collaborating with cross-functional teams to ensure scientific excellence and regulatory compliance while m...

RemoteRemote

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$85K *

Champion the development and oversight of ABA treatment plans while mentoring a dedicated team of Behavior Technicians, ensuring effective collaborations with diverse families for impactful therapeuti...

RemoteRemote

Reposted 1 week ago

  •   Less than 5 years exp.  •   Healthcare

$80K - $95K *

Advance your career by leading a dynamic rehab therapy team, ensuring high-quality patient care and fostering professional development while managing operations and interdisciplinary collaboration...

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$140K - $210K *

Partner with us to drive innovative financial solutions in the healthcare sector. Leverage your Workday expertise for impactful implementations, collaborating closely with teams to transform operation...

RemoteRemote

Reposted 1 week ago

  •   5 - 7 years exp.  •   Consumer Technology

$79K - $90K *

Join a team that's dedicated to delivering exceptional nursing care, positively impacting lives through quality patient support and collaboration in a dynamic clinical environment. Flexible scheduling...

1 week ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$95K - $115K *

Elevate your career by providing exceptional pre-operative and post-anesthesia care. Collaborate with a multidisciplinary team to ensure quality patient outcomes while contributing to education and re...

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$112K - $197K *

Lead our pharmacy team to enhance patient care and community health through effective operations, compliance, and outreach initiatives. Drive performance and ensure exceptional service while managing...

1 week ago

  •   Less than 5 years exp.  •   Retail & Consumer Goods

$85K - $100K *

Transform healthcare analytics by supporting ACOs in the MSSP program. Leverage data-driven insights to track performance metrics, optimize risk scores, and collaborate with teams to enhance value-bas...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$85K - $100K *

Manage and optimize nursing documentation practices in electronic health records, ensuring safe, efficient patient care. Lead training and support initiatives while collaborating with clinical teams t...

1 week ago

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$149K - $298K *

Lead strategic and operational initiatives for field clinical teams, ensuring compliance and effective trial support for TMVR programs while driving positive patient outcomes and team performance...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Healthcare

$67K - $111K *

Deliver compassionate, expert behavioral health care throughout members' journeys, ensuring clinical excellence in a fast-paced, 24/7 environment as a trusted clinical partner in diverse cases and sup...

United StatesRemote

Reposted 1 week ago

  •   5 - 7 years exp.  •   Healthcare

$90K - $110K *

Advance patient care in a collaborative healthcare environment. As a Nurse Practitioner, you'll assess, diagnose, and treat patients while coordinating care across multiple programs, ensuring high-qua...

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$80K - $95K *

Join a team that's dedicated to enhancing patient safety through data analysis, audits, and collaboration across departments. Drive improvements in EHR software and support quality initiatives to ensu...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Healthcare

$210K - $250K *

Unlock potential by leveraging your GI expertise to enhance product development, strengthen customer relationships, and drive growth in a dynamic SaaS environment. Collaborate across teams to deliver...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Healthcare

$80K - $95K *

Inspire excellence in nursing care by leading clinical teams to achieve high-quality standards. Drive positive change, foster a supportive culture, and ensure that residents receive top-tier care tail...

Reposted 1 week ago

  •   5 - 7 years exp.  •   Hospitals & Medical Centers

$195K - $256K *

Elevate clinical quality assurance by designing and executing strategies for compliance, audit management, and oversight of global clinical operations. Collaborate with stakeholders to ensure adherenc...

United StatesRemote

1 week ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$77K - $202K *

Drive impactful change in healthcare payer operations by analyzing complex challenges, managing workstreams, and guiding teams to enhance technology and service delivery models. Collaborate with clien...

1 week ago

  •   Less than 5 years exp.  •   Legal & Accounting

$85K - $100K *

Shape the future of nursing informatics by leading documentation practices and optimizing electronic health records to enhance patient care and clinical workflows. Collaborate with teams to ensure saf...

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$90K *

Support the optimization and configuration of Epic EHR systems, collaborating with clinical teams to enhance workflows, ensure compliance, and provide technical assistance, while maintaining system pe...

1 week ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$90K *

Lead the charge in optimizing clinical workflows by configuring and supporting Epic EHR systems. Collaborate with healthcare teams to enhance system performance, ensure compliance, and provide trainin...

1 week ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$90K *

Shape the future of healthcare technology by optimizing Epic EHR systems. Collaborate with clinical teams to enhance workflows, ensure compliance, and provide technical support, all while driving cont...

1 week ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

Frequently Asked Questions (FAQ)

  • What kinds of $100,000+ jobs are available in Iowa?question toggle

    Listings may include opportunities in healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Roles and salary ranges vary by employer and experience.

  • Which Iowa cities have professional jobs listed?question toggle

    Explore opportunities in Des Moines, Cedar Rapids, Iowa City, Davenport, Sioux City, and other Iowa locations. Remote or hybrid openings may also be available.

  • Are all jobs on this page guaranteed to pay at least $100,000?question toggle

    Ladders focuses on professional jobs paying $100,000 or more, but compensation and eligibility can vary. Review each listing for its specific salary information and requirements.

  • How can I find the right high-paying job in Iowa?question toggle

    Use filters for location, job title, and other preferences, then compare responsibilities and qualifications. Keeping your resume updated and setting job alerts can help you respond to relevant openings.