Discover professional opportunities across Pennsylvania with Ladders, where job seekers can explore vetted roles paying $100,000 or more. From major business centers like Philadelphia and Pittsburgh to growing communities throughout the state, Pennsylvania offers opportunities for experienced professionals across a range of industries.
Search for roles in Pennsylvania’s largest cities and regional hubs. Whether you’re considering a move to Philadelphia, Pittsburgh, Harrisburg, or another location, you can browse openings and compare opportunities by job title, location, and other relevant criteria.
Pennsylvania’s economy spans sectors such as healthcare, financial services, technology, manufacturing, education, and energy. The roles available vary by employer and location, so use search filters to focus on positions that align with your expertise, career goals, and preferred work arrangement.
Ladders focuses on professional jobs with salaries of $100,000 or more. Review listings for details about responsibilities, qualifications, compensation, and location, then apply directly to opportunities that match your experience.
Browse Pennsylvania job listings to find your next career opportunity. Narrow your search by city, function, or seniority to identify roles suited to your background and ambitions.
$88K - $154K *
Transform your career by leading full-lifecycle recruiting for federal proposals, focusing on defense and intelligence sectors. Collaborate with teams to develop strategies, source talent, and ensure...
2 days ago
Project Manager, FEHRM Healthcare Technology Management - Deployment
$95K - $125K *
Drive the deployment of healthcare technology across multiple VA facilities, coordinating projects and ensuring readiness. Collaborate with diverse teams to manage timelines, resolve issues, and deliv...
3 weeks ago
Senior Bioinformatics & Genomics Data System Engineer
$113K - $142K *
Elevate your career by joining our dynamic team to design, develop, and optimize bioinformatics software tools and systems, ensuring robust functionality and compliance in a fast-paced, innovative env...
2 days ago
$112K - $135K *
Empower innovation by developing advanced cloud-native security solutions. Collaborate with cross-functional teams to create secure applications, focusing on authentication and authorization capabilit...
3 weeks ago
Sr. Manager, AI Performance & Operations
$110K - $173K *
Join a team that's redefining AI-driven quality and performance operations. You'll build systems that enhance frontline team effectiveness and AI agent performance, ensuring impactful coaching and fee...
4 weeks ago
Lead Machine Learning Software Engineer
$130K - $155K *
Shape the future of healthcare by leading innovative machine learning software engineering initiatives. Collaborate with a multidisciplinary team to enhance patient care and operational efficiency thr...
4 days ago
RN - Registered Nurse - Regional Manager Clinical Risk and Patient Safety
$85K - $100K *
Transform patient safety and risk management by leading initiatives that enhance quality care and compliance across the region. Collaborate with healthcare leaders to drive improvements and ensure a s...
3 weeks ago
$105K - $129K *
Champion comprehensive care by leading an outpatient practice, managing clinical operations, and enhancing resident well-being in a dynamic healthcare environment focused on geriatrics and long-term c...
2 weeks ago
$89K - $113K *
Transform data integrity by assisting in the analysis and cleansing of Enterprise Business Systems. Collaborate with teams to resolve anomalies and ensure compliance with DoD standards while supportin...
6 days ago
$140K - $170K *
Elevate your career by managing a dynamic Palliative Care Program, providing clinical expertise, and leading a dedicated team. Drive process improvements and ensure high-quality patient care while fos...
3 weeks ago
Nurse Practitioner (PRN) - In-Home Health Assessments
$115K - $138K *
Champion comprehensive health assessments by conducting in-home evaluations, collaborating with healthcare teams, and enhancing patient care. Enjoy flexible scheduling and competitive pay while making...
3 weeks ago
IT Business Management Senior Analyst
$88K - $105K *
Unlock insights into cloud spending by analyzing AWS and Azure costs, producing dashboards, and optimizing resources. Collaborate with teams to drive efficiency and savings while enhancing your analyt...
Yesterday
Senior Sales Compensation Analyst
$68K - $113K *
Unlock potential by leading complex sales compensation analysis and strategy. Collaborate with senior leaders to design and enhance incentive programs, leveraging advanced analytics to drive performan...
2 weeks ago
$72K - $192K *
Join a team that's dedicated to enhancing client relationships in healthcare. As a trusted advisor, you'll guide clients through workflows, drive feature adoption, and develop strategic plans to maxim...
3 days ago
$68K - $143K *
Unlock innovative financial processes by driving transformation in logistics integration and optimizing resource allocation. Collaborate with diverse teams to enhance financial operations within the D...
Reposted 1 week ago
$80K - $95K *
Unlock potential by monitoring clinical trials, ensuring compliance, data integrity, and patient safety while collaborating with investigators to advance innovative therapies and improve health outcom...
Reposted 1 week ago
Senior Consultant - Health & Welfare Benefits
$170K - $220K *
Lead the strategic direction of Taft-Hartley multiemployer health plans, guiding trustees through benefit design and compliance while optimizing funding strategies to enhance long-term sustainability...
Reposted 3 days ago
$118K - $196K *
Unlock your potential in a dynamic role focused on drug formulary development, compliance, and utilization management. Collaborate with cross-functional teams to enhance pharmacy strategies and improv...
Yesterday
$113K - $188K *
Join a dynamic team to design and develop high-performance ETL solutions, integrating data from diverse sources. Collaborate with cross-functional teams to optimize data workflows and ensure complianc...
2 weeks ago
Director, Revenue Analytics, Reporting & Strategy
$110K - $130K *
Drive your career forward by leveraging analytical skills to improve the financial efficiency of patient revenue cycles, ensuring compliance and accuracy in reporting while collaborating with key stak...
Reposted 6 days ago
Associate Director, Early Portfolio Alliance Management & Operations
$135K - $160K *
Join a team that drives innovation in early-stage oncology partnerships, ensuring alignment of scientific and corporate goals while managing cross-functional collaboration and governance for impactful...
Reposted 5 days ago
Associate Director, Early Portfolio Alliance Management & Operations
$145K - $175K *
Drive strategic innovation in early-portfolio alliance management, fostering collaborations to advance oncology projects from discovery through clinical stages. Collaborate with diverse teams to ensur...
Reposted 5 days ago
$110K *
Take ownership of complex mortgage loan evaluations, ensuring compliance with guidelines while assessing borrower risk. Collaborate with internal teams and vendors to facilitate loan approvals and mai...
2 weeks ago
$135K - $160K *
Help us design and deliver innovative data and AI solutions that transform complex data into actionable insights, supporting critical decisions across various sectors while leading technical standards...
1 month ago
$115K - $130K *
Analyze market trends and performance metrics to drive actionable insights across marketing, sales, and revenue operations. Collaborate with cross-functional teams to optimize strategies and enhance g...
1 week ago
What kinds of high-paying jobs can I find in Pennsylvania?
Pennsylvania listings may include senior and professional roles across fields such as healthcare, finance, technology, manufacturing, education, and energy. Available positions vary by employer and location.
Which Pennsylvania cities have professional job opportunities?
Opportunities may be available in Philadelphia, Pittsburgh, Harrisburg, and other cities and communities across the state. Browse current listings to see where employers are hiring.
Do Pennsylvania jobs on Ladders pay at least $100,000?
Ladders focuses on vetted professional jobs paying $100,000 or more. Check each listing for its compensation details and any applicable salary range.
How can I narrow my search for jobs in Pennsylvania?
Use search filters such as location, job title, industry, and seniority to focus on opportunities that fit your experience and preferences.
Are remote or hybrid jobs available in Pennsylvania?
Some listings may offer remote or hybrid arrangements, depending on the employer and position. Review each job description for its work-location details.