Discover professional opportunities across Pennsylvania with Ladders, where job seekers can explore vetted roles paying $100,000 or more. From major business centers like Philadelphia and Pittsburgh to growing communities throughout the state, Pennsylvania offers opportunities for experienced professionals across a range of industries.
Search for roles in Pennsylvania’s largest cities and regional hubs. Whether you’re considering a move to Philadelphia, Pittsburgh, Harrisburg, or another location, you can browse openings and compare opportunities by job title, location, and other relevant criteria.
Pennsylvania’s economy spans sectors such as healthcare, financial services, technology, manufacturing, education, and energy. The roles available vary by employer and location, so use search filters to focus on positions that align with your expertise, career goals, and preferred work arrangement.
Ladders focuses on professional jobs with salaries of $100,000 or more. Review listings for details about responsibilities, qualifications, compensation, and location, then apply directly to opportunities that match your experience.
Browse Pennsylvania job listings to find your next career opportunity. Narrow your search by city, function, or seniority to identify roles suited to your background and ambitions.
$100K - $122K *
Unlock potential by leading a dynamic accounting team, managing full-cycle accounting processes, ensuring compliance, and driving process improvements in a fast-paced environment. Collaborate with fin...
4 weeks ago
Account Executive (HCM, Payroll, Saas, Healthcare)
$76K - $102K *
Engage in a dynamic role driving client acquisition in the Home-Based Care sector. You'll build a robust pipeline, execute sales strategies, and collaborate cross-functionally to enhance client experi...
3 weeks ago
Senior Application Migration Business Analyst
$140K - $211K *
Lead the charge in transforming enterprise applications through cloud migration. Drive global initiatives, mentor teams, and solve complex challenges while ensuring seamless transitions to Azure and A...
2 days ago
AVP, Vendor Strategy & Cost Management
$163K - $220K *
Transform vendor strategies and cost management across the organization. Drive financial performance with analytics, lead sourcing events, and collaborate with cross-functional teams to optimize value...
Reposted 2 weeks ago
$90K - $110K *
Shape the future of consumer lending by analyzing credit risk and performance data to drive strategic insights for financial institutions, optimizing their underwriting processes and enhancing portfol...
Reposted 3 weeks ago
$80K - $95K *
Join us to drive acquisition projects by translating customer needs into actionable procurement strategies, developing essential documentation, and ensuring effective program management throughout the...
Yesterday
Medical Science Liaison, Rare Neurology, Eastern PA/Upstate NY
$152K - $228K *
Explore a dynamic role as a Medical Science Liaison, where you'll engage with healthcare professionals, drive scientific exchange, and support strategic medical objectives in the rare disease sector...
3 weeks ago
Medical Science Liaison, Rare Neurology, Eastern PA/Upstate NY
$152K - $228K *
Shape the future of rare disease treatment by managing HCP relationships, providing scientific expertise, and driving collaboration within a dynamic healthcare environment. Leverage your clinical know...
3 weeks ago
Physician Assistant- Primary Care
$90K - $110K *
Join a team that champions comprehensive pain management for Veterans, utilizing advanced clinical skills to assess, plan, and implement individualized care in a collaborative environment focused on i...
Yesterday
Hospice RN Case Manager (Montgomery County, PA)
$90K *
Empower patients and families as a Hospice RN Case Manager, providing compassionate care through skilled assessments and interdisciplinary collaboration. Manage caseloads effectively while ensuring op...
5 days ago
Technical IBM Mainframe Applications/Systems Analyst
$75K - $105K *
Optimize mainframe systems as a key analyst, ensuring stability and performance of IBM z/OS environments. Collaborate with teams to troubleshoot issues and maintain critical applications, while enhanc...
1 week ago
Cybersecurity A&A Risk Analyst
$110K - $112K *
Elevate your career by providing advanced governance, risk, and compliance support for federal information systems, ensuring compliance with federal laws and regulations while engaging with key stakeh...
2 weeks ago
Staff Software Engineer - Data Platform (HL7) (R37)
$212K - $409K *
Drive innovation as a key member of our engineering team, leveraging your expertise in software engineering and data platforms to shape solutions that enhance customer experiences and meet business go...
3 weeks ago
Manager of Statistical Programming
$132K - $165K *
Drive innovation in oncology diagnostics by leading statistical programming efforts, ensuring data integrity and compliance for clinical trials, while managing a team and collaborating cross-functiona...
2 weeks ago
$100K - $120K *
Drive strategic oversight of enterprise-wide RAC audit activities, ensuring compliance and operational excellence. Collaborate with leadership to enhance audit processes, minimize financial risk, and...
1 week ago
Enterprise Service and Configuration Management Analyst
$66K - $106K *
Optimize IT service delivery by managing configuration items, analyzing operational data, and ensuring effective incident resolution. Collaborate with cross-functional teams to enhance service perform...
3 weeks ago
Physician Assistant - Interventional Radiology
$90K - $110K *
Support a dynamic Interventional Radiology team by managing patient care, performing procedures, and collaborating with healthcare professionals to enhance patient outcomes in a fast-paced, academic e...
4 days ago
$95K - $115K *
Lead the charge in advancing Factory automation and IT infrastructure strategy, focusing on modernization and innovation. Collaborate with teams to enhance operational efficiency and ensure secure, hi...
Reposted 4 days ago
Director of Clinical Services-Behavioral Health
$90K - $110K *
Lead the clinical services at a premier behavioral health facility, driving strategic planning and program development to enhance community care and meet performance goals in a supportive environment...
1 week ago
Associate - Financial Planning & Analysis (FP&A)
$80K - $95K *
Empower your career by driving financial insights and analytics. Collaborate across teams to transform data into strategic decisions, enhancing growth and efficiency in a dynamic environment. Join us...
5 days ago
Director, Biotech Strategy Lead - General Medicine/ Metabolic
$150K - $180K *
Champion innovative clinical development strategies in General Medicine/Metabolic. Collaborate with cross-functional teams to deliver tailored solutions, leveraging deep therapeutic expertise to drive...
3 days ago
$103K - $128K *
Join us to lead product strategy and development, driving innovation and performance in healthcare solutions. Collaborate cross-functionally to align business needs with customer expectations and ensu...
3 weeks ago
Director of Advanced Practice Providers- Pennsylvania Hospital
$125K - $150K *
Elevate your career by leading advanced practice providers in strategic planning, operational excellence, and professional development. Drive initiatives that enhance patient care and optimize team pe...
1 week ago
Senior Consultant--Homelessness and Human Services
$80K - $135K *
Empower communities by leading strategic initiatives in homelessness services. Utilize your expertise to enhance organizational capacity, improve service coordination, and drive sustainable solutions...
4 days ago
$88K - $154K *
Transform your career by leading full-lifecycle recruiting for federal proposals, focusing on defense and intelligence sectors. Collaborate with teams to develop strategies, source talent, and ensure...
2 days ago
What kinds of high-paying jobs can I find in Pennsylvania?
Pennsylvania listings may include senior and professional roles across fields such as healthcare, finance, technology, manufacturing, education, and energy. Available positions vary by employer and location.
Which Pennsylvania cities have professional job opportunities?
Opportunities may be available in Philadelphia, Pittsburgh, Harrisburg, and other cities and communities across the state. Browse current listings to see where employers are hiring.
Do Pennsylvania jobs on Ladders pay at least $100,000?
Ladders focuses on vetted professional jobs paying $100,000 or more. Check each listing for its compensation details and any applicable salary range.
How can I narrow my search for jobs in Pennsylvania?
Use search filters such as location, job title, industry, and seniority to focus on opportunities that fit your experience and preferences.
Are remote or hybrid jobs available in Pennsylvania?
Some listings may offer remote or hybrid arrangements, depending on the employer and position. Review each job description for its work-location details.